Functional and Molecular Diversity of Native Neuronal K+ Channels

[1]  F. Laezza,et al.  Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K+ current inhibition mediated by activation of caspases and GSK-3 , 2015, Neurobiology of Aging.

[2]  M. Amalric,et al.  Kv4 channel blockade reduces motor and neuropsychiatric symptoms in rodent models of Parkinson's disease. , 2015, Behavioural pharmacology.

[3]  K. Takimoto,et al.  Differential contribution of Kv4-containing channels to A-type, voltage-gated potassium currents in somatic and visceral dorsal root ganglion neurons. , 2014, Journal of neurophysiology.

[4]  L. Kaczmarek,et al.  More Than a Pore: Ion Channel Signaling Complexes , 2014, The Journal of Neuroscience.

[5]  B. Fakler,et al.  Mutant α-Synuclein Enhances Firing Frequencies in Dopamine Substantia Nigra Neurons by Oxidative Impairment of A-Type Potassium Channels , 2014, The Journal of Neuroscience.

[6]  J. Nerbonne,et al.  Characterization of SEMA3A-Encoded Semaphorin as a Naturally Occurring Kv4.3 Protein Inhibitor and its Contribution to Brugada Syndrome , 2014, Circulation research.

[7]  L. Kaczmarek,et al.  Emerging role of the KCNT1 Slack channel in intellectual disability , 2014, Front. Cell. Neurosci..

[8]  Lucas Cheadle,et al.  Activity-Dependent Regulation of Dendritic Complexity by Semaphorin 3A through Farp1 , 2014, The Journal of Neuroscience.

[9]  Masahiko Watanabe,et al.  Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain , 2014, Science.

[10]  S. Nelson,et al.  Exome sequencing identifies de novo gain of function missense mutation in KCND2 in identical twins with autism and seizures that slows potassium channel inactivation. , 2014, Human molecular genetics.

[11]  Peter Donnelly,et al.  Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis , 2014, Human molecular genetics.

[12]  H. Wulff,et al.  The therapeutic potential of small-conductance KCa2 channels in neurodegenerative and psychiatric diseases , 2013, Expert opinion on therapeutic targets.

[13]  R. Latorre,et al.  A BK (Slo1) channel journey from molecule to physiology , 2013, Channels.

[14]  A. Durr,et al.  The L450P mutation in KCND3 brings spinocerebellar ataxia and Brugada syndrome closer together , 2013, neurogenetics.

[15]  L. Kaczmarek.  Slack, Slick, and Sodium-Activated Potassium Channels , 2013, ISRN neuroscience.

[16]  W Hamish Mehaffey,et al.  The Cav3–Kv4 Complex Acts as a Calcium Sensor to Maintain Inhibitory Charge Transfer during Extracellular Calcium Fluctuations , 2013, The Journal of Neuroscience.

[17]  L. Kaczmarek,et al.  A sodium-activated potassium channel supports high-frequency firing and reduces energetic costs during rapid modulations of action potential amplitude. , 2013, Journal of neurophysiology.

[18]  S. D. Moore,et al.  The Auxiliary Subunit KChIP2 Is an Essential Regulator of Homeostatic Excitability* , 2013, The Journal of Biological Chemistry.

[19]  C. Wijmenga,et al.  Mutations in potassium channel kcnd3 cause spinocerebellar ataxia type 19 , 2012, Annals of neurology.

[20]  P. Tsai,et al.  Mutations in KCND3 cause spinocerebellar ataxia type 22 , 2012, Annals of neurology.

[21]  L. Kaczmarek,et al.  De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy , 2012, Nature Genetics.

[22]  L. Kaczmarek,et al.  Regulation of Neuronal Excitability by Interaction of Fragile X Mental Retardation Protein with Slack Potassium Channels , 2012, The Journal of Neuroscience.

[23]  A. Burkhalter,et al.  A‐type K+ channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons , 2012, The Journal of physiology.

[24]  Andrew J Link,et al.  The Sodium Channel Accessory Subunit Navβ1 Regulates Neuronal Excitability through Modulation of Repolarizing Voltage-Gated K+ Channels , 2012, The Journal of Neuroscience.

[25]  L. Salkoff,et al.  Sodium-Activated Potassium Channels Are Functionally Coupled to Persistent Sodium Currents , 2012, The Journal of Neuroscience.

[26]  P. Sah,et al.  Small-conductance Ca2+-activated K+ channels: form and function. , 2012, Annual review of physiology.

[27]  Y. Jan,et al.  Bidirectional Regulation of Dendritic Voltage-Gated Potassium Channels by the Fragile X Mental Retardation Protein , 2011, Neuron.

[28]  D. Hoffman,et al.  DPP6 Establishes the A-Type K+ Current Gradient Critical for the Regulation of Dendritic Excitability in CA1 Hippocampal Neurons , 2011, Neuron.

[29]  Paul M. Jenkins,et al.  Subunit-Dependent Axonal Trafficking of Distinct α Heteromeric Potassium Channel Complexes , 2011, The Journal of Neuroscience.

[30]  A. Jeromin,et al.  Fragile X Mental Retardation Protein Regulates Protein Expression and mRNA Translation of the Potassium Channel Kv4.2 , 2011, The Journal of Neuroscience.

[31]  J. Nerbonne,et al.  Proteomic analysis highlights the molecular complexities of native Kv4 channel macromolecular complexes. , 2011, Seminars in cell & developmental biology.

[32]  D. Hoffman,et al.  AKAP79/150 Impacts Intrinsic Excitability of Hippocampal Neurons through Phospho-Regulation of A-type K+ Channel Trafficking , 2011, The Journal of Neuroscience.

[33]  J. Nerbonne,et al.  Interdependent Roles for Accessory KChIP2, KChIP3, and KChIP4 Subunits in the Generation of Kv4-Encoded IA Channels in Cortical Pyramidal Neurons , 2010, The Journal of Neuroscience.

[34]  Co-assembly of Kv4 α Subunits with K+ Channel-interacting Protein 2 Stabilizes Protein Expression and Promotes Surface Retention of Channel Complexes* , 2010, The Journal of Biological Chemistry.

[35]  P. Pfaffinger,et al.  Dipeptidyl Peptidase-Like Protein 6 Is Required for Normal Electrophysiological Properties of Cerebellar Granule Cells , 2010, The Journal of Neuroscience.

[36]  J. Nerbonne,et al.  Molecular Dissection of IA in Cortical Pyramidal Neurons Reveals Three Distinct Components Encoded by Kv4.2, Kv4.3, and Kv1.4 α-Subunits , 2010, The Journal of Neuroscience.

[37]  Shahid Hameed,et al.  Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes , 2010, Nature Neuroscience.

[38]  A. Sehgal,et al.  SLEEPLESS, a Ly–6/Neurotoxin Family Member, Regulates Levels, Localization, and Activity of Shaker , 2009, Nature Neuroscience.

[39]  M. Covarrubias,et al.  Kv4 Channels Underlie the Subthreshold-Operating A-type K+-current in Nociceptive Dorsal Root Ganglion Neurons , 2009, Front. Mol. Neurosci..

[40]  Jinhyung Kim,et al.  Kv4 accessory protein DPPX (DPP6) is a critical regulator of membrane excitability in hippocampal CA1 pyramidal neurons. , 2008, Journal of neurophysiology.

[41]  Andrew M. Wikenheiser,et al.  Protein Kinase A Mediates Activity-Dependent Kv4.2 Channel Trafficking , 2008, The Journal of Neuroscience.

[42]  Sung-Cherl Jung,et al.  Regulation of Dendritic Excitability by Activity-Dependent Trafficking of the A-Type K+ Channel Subunit Kv4.2 in Hippocampal Neurons , 2007, Neuron.

[43]  A. Burkhalter,et al.  Differential Expression of IA Channel Subunits Kv4.2 and Kv4.3 in Mouse Visual Cortical Neurons and Synapses , 2006, The Journal of Neuroscience.

[44]  Kazumi Matsuda,et al.  A Kv4.2 truncation mutation in a patient with temporal lobe epilepsy , 2006, Neurobiology of Disease.

[45]  Jinhyung Kim,et al.  Kv4 potassium channel subunits control action potential repolarization and frequency‐dependent broadening in rat hippocampal CA1 pyramidal neurones , 2005, The Journal of physiology.

[46]  D. Johnston,et al.  Calcium–Calmodulin-Dependent Kinase II Modulates Kv4.2 Channel Expression and Upregulates Neuronal A-Type Potassium Currents , 2004, The Journal of Neuroscience.

[47]  Ethan M. Goldberg,et al.  The CD26-Related Dipeptidyl Aminopeptidase-like Protein DPPX Is a Critical Component of Neuronal A-Type K+ Channels , 2003, Neuron.

[48]  D. Johnston,et al.  Protein Kinase Modulation of Dendritic K+ Channels in Hippocampus Involves a Mitogen-Activated Protein Kinase Pathway , 2002, The Journal of Neuroscience.

[49]  J. Nerbonne,et al.  Molecular Heterogeneity of the Voltage-Gated Fast Transient Outward K+ Current, IAf, in Mammalian Neurons , 2001, The Journal of Neuroscience.

[50]  Detlef Bockenhauer,et al.  Potassium leak channels and the KCNK family of two-p-domain subunits , 2001, Nature Reviews Neuroscience.

[51]  A. Shrier,et al.  Localization and Enhanced Current Density of the Kv4.2 Potassium Channel by Interaction with the Actin-Binding Protein Filamin , 2000, The Journal of Neuroscience.

[52]  J. Nerbonne,et al.  Elimination of the Fast Transient in Superior Cervical Ganglion Neurons with Expression of KV4.2W362F: Molecular Dissection ofIA , 2000, The Journal of Neuroscience.

[53]  M Migliore,et al.  Dendritic potassium channels in hippocampal pyramidal neurons , 2000, The Journal of physiology.

[54]  K. Rhodes,et al.  Modulation of A-type potassium channels by a family of calcium sensors , 2000, Nature.

[55]  Alcino J. Silva,et al.  Functional and Molecular Aspects of Voltage‐Gated K+ Channel β Subunits , 1999, Annals of the New York Academy of Sciences.

[56]  B. Rudy,et al.  Molecular Diversity of K+ Channels , 1999, Annals of the New York Academy of Sciences.

[57]  G. Abbott,et al.  A superfamily of small potassium channel subunits: form and function of the MinK-related peptides (MiRPs) , 1998, Quarterly Reviews of Biophysics.

[58]  Y. Jan,et al.  Presynaptic Localization of Kv1.4-Containing A-Type Potassium Channels Near Excitatory Synapses in the Hippocampus , 1998, The Journal of Neuroscience.

[59]  Y. Jan,et al.  Subcellular segregation of two A-type K+ channel proteins in rat central neurons , 1992, Neuron.

[60]  C. Stevens,et al.  Voltage clamp studies of a transient outward membrane current in gastropod neural somata , 1971, The Journal of physiology.