Analysis of circulating angiopoietin-like protein 3 and genetic variants in lipid metabolism and liver health: the DiOGenes study

[1]  A. Valsesia,et al.  Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator , 2017, Nature Communications.

[2]  Nicola J. Rinaldi,et al.  Genetic effects on gene expression across human tissues , 2017, Nature.

[3]  A. Valsesia,et al.  Transcriptome profiling from adipose tissue during a low-calorie diet reveals predictors of weight and glycemic outcomes in obese, nondiabetic subjects. , 2017, The American journal of clinical nutrition.

[4]  S. Shetty,et al.  ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase , 2017, Molecular metabolism.

[5]  Jonathan C. Cohen,et al.  ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance[S] , 2017, Journal of Lipid Research.

[6]  Helen E. Parkinson,et al.  The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog) , 2016, Nucleic Acids Res..

[7]  A. Yang,et al.  Association and interaction of APOA5, BUD13, CETP, LIPA and health-related behavior with metabolic syndrome in a Taiwanese population , 2016, Scientific Reports.

[8]  P. Stewart,et al.  SFRP2 Is Associated with Increased Adiposity and VEGF Expression , 2016, PloS one.

[9]  A. Valsesia,et al.  Distinct lipid profiles predict improved glycemic control in obese, nondiabetic patients after a low-caloric diet intervention: the Diet, Obesity and Genes randomized trial. , 2016, The American journal of clinical nutrition.

[10]  Alan M. Kwong,et al.  Next-generation genotype imputation service and methods , 2016, Nature Genetics.

[11]  S. Kersten,et al.  Regulation of lipid metabolism by angiopoietin-like proteins , 2016, Current opinion in lipidology.

[12]  Ren Zhang.  The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking , 2016, Open Biology.

[13]  M. Jauhiainen,et al.  The role of ANGPTL3 in controlling lipoprotein metabolism , 2016, Endocrine.

[14]  Mitchell J. Machiela,et al.  LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants , 2015, Bioinform..

[15]  Juan Chen,et al.  Effects of Polymorphisms in APOA4-APOA5-ZNF259-BUD13 Gene Cluster on Plasma Levels of Triglycerides and Risk of Coronary Heart Disease in a Chinese Han Population , 2015, PloS one.

[16]  P. Fischer-Posovszky,et al.  Regulation of Angiopoietin-Like Proteins (ANGPTLs) 3 and 8 by Insulin. , 2015, The Journal of clinical endocrinology and metabolism.

[17]  Larry Gold,et al.  Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents , 2014, Molecular therapy. Nucleic acids.

[18]  Hui Li,et al.  Association between the MLX Interacting Protein-Like, BUD13 Homolog and Zinc Finger Protein 259 Gene Polymorphisms and Serum Lipid Levels , 2014, Scientific Reports.

[19]  M. Reilly,et al.  Differential Association of Plasma Angiopoietin-Like Proteins 3 and 4 With Lipid and Metabolic Traits , 2014, Arteriosclerosis, thrombosis, and vascular biology.

[20]  Wei Wang,et al.  Association of the variants in the BUD13-ZNF259 genes and the risk of hyperlipidaemia , 2014, Journal of cellular and molecular medicine.

[21]  D. Rader,et al.  Angptl3 Deficiency Is Associated With Increased Insulin Sensitivity, Lipoprotein Lipase Activity, and Decreased Serum Free Fatty Acids , 2013, Arteriosclerosis, thrombosis, and vascular biology.

[22]  Jonathan C. Cohen,et al.  Atypical angiopoietin-like protein that regulates ANGPTL3 , 2012, Proceedings of the National Academy of Sciences.

[23]  G. Labbadia,et al.  Mutations in the ANGPTL3 gene and familial combined hypolipidemia: a clinical and biochemical characterization. , 2012, The Journal of clinical endocrinology and metabolism.

[24]  P. Visscher,et al.  GCTA: a tool for genome-wide complex trait analysis. , 2011, American journal of human genetics.

[25]  M. Dijkstra,et al.  Comparative analysis of the human hepatic and adipose tissue transcriptomes during LPS-induced inflammation leads to the identification of differential biological pathways and candidate biomarkers , 2011, BMC Medical Genomics.

[26]  Jonathan C. Cohen,et al.  Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia. , 2010, The New England journal of medicine.

[27]  A. Astrup,et al.  Diets with high or low protein content and glycemic index for weight-loss maintenance. , 2010, The New England journal of medicine.

[28]  Tracy R. Keeney,et al.  Aptamer-based multiplexed proteomic technology for biomarker discovery , 2010, PloS one.

[29]  Kun Han,et al.  Design Strategies for Aptamer-Based Biosensors , 2010, Italian National Conference on Sensors.

[30]  M. Jauhiainen,et al.  Quantitation of serum angiopoietin-like proteins 3 and 4 in a Finnish population sample , 2010, Journal of Lipid Research.

[31]  T. Larsen,et al.  The Diet, Obesity and Genes (Diogenes) Dietary Study in eight European countries – a comprehensive design for long‐term intervention , 2010, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[32]  J. Ordovás,et al.  Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men[S] , 2010, Journal of Lipid Research.

[33]  A. Astrup,et al.  Dietary strategy to manipulate ad libitum macronutrient intake, and glycaemic index, across eight European countries in the Diogenes Study , 2010, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[34]  Y. Hu,et al.  GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4 , 2009, Journal of Lipid Research.

[35]  H. Koyama,et al.  Plasma angiopoietin-like protein 3 (ANGPTL3) concentration is associated with uremic dyslipidemia. , 2009, Atherosclerosis.

[36]  Avinash A. K. Math,et al.  A review on laboratory liver function tests , 2009, The Pan African medical journal.

[37]  E. Ulukaya,et al.  Serum concentrations of human angiopoietin-like protein 3 in patients with nonalcoholic fatty liver disease: association with insulin resistance , 2009, European journal of gastroenterology & hepatology.

[38]  C. Perou,et al.  Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathway. , 2009, Cancer research.

[39]  Eleazar Eskin,et al.  Rapid and Accurate Multiple Testing Correction and Power Estimation for Millions of Correlated Markers , 2009, PLoS genetics.

[40]  Y. Hu,et al.  The Angiopoietin-like Proteins ANGPTL3 and ANGPTL4 Inhibit Lipoprotein Lipase Activity through Distinct Mechanisms* , 2009, Journal of Biological Chemistry.

[41]  Eric Boerwinkle,et al.  Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. , 2008, The Journal of clinical investigation.

[42]  P. Schauer,et al.  Cytokeratin 18 fragment levels as a noninvasive biomarker for nonalcoholic steatohepatitis in bariatric surgery patients. , 2008, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[43]  S. Grundy.  Metabolic Syndrome Pandemic , 2008, Arteriosclerosis, thrombosis, and vascular biology.

[44]  M. Tabata,et al.  The role of angiopoietin-like proteins in angiogenesis and metabolism. , 2008, Trends in cardiovascular medicine.

[45]  D. Stejskal,et al.  Angiopoietin-like protein 3: development, analytical characterization, and clinical testing of a new ELISA. , 2007, General physiology and biophysics.

[46]  Yurii S. Aulchenko,et al.  BIOINFORMATICS APPLICATIONS NOTE doi:10.1093/bioinformatics/btm108 Genetics and population analysis GenABEL: an R library for genome-wide association analysis , 2022 .

[47]  ShizuyaYamashita,et al.  Angiopoietin-Like Protein3 Regulates Plasma HDL Cholesterol Through Suppression of Endothelial Lipase , 2007 .

[48]  S. Fukumoto,et al.  Association between Plasma Angiopoietin-Like Protein 3 and Arterial Wall Thickness in Healthy Subjects , 2006, Journal of Vascular Research.

[49]  C. Fraser,et al.  Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism. , 2005, Endocrinology.

[50]  Vincenzo Savarino,et al.  Liver enzyme alteration: a guide for clinicians , 2005, Canadian Medical Association Journal.

[51]  Kenichi Yoshida,et al.  Protein Region Important for Regulation of Lipid Metabolism in Angiopoietin-like 3 (ANGPTL3) , 2003, Journal of Biological Chemistry.

[52]  Kenichi Yoshida,et al.  ANGPTL3 Decreases Very Low Density Lipoprotein Triglyceride Clearance by Inhibition of Lipoprotein Lipase* , 2002, The Journal of Biological Chemistry.

[53]  T. Fujiwara,et al.  Angptl3 regulates lipid metabolism in mice , 2002, Nature Genetics.

[54]  S. Wattler,et al.  Identification of a mammalian angiopoietin-related protein expressed specifically in liver. , 1999, Genomics.

[55]  R. Levy,et al.  Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. , 1972, Clinical chemistry.