Curvature, lipid packing, and electrostatics of membrane organelles: defining cellular territories in determining specificity.

[1]  G. van den Bogaart,et al.  Controlling synaptotagmin activity by electrostatic screening , 2012, Nature Structural &Molecular Biology.

[2]  Yi I. Wu,et al.  External push and internal pull forces recruit curvature sensing N-BAR domain proteins to the plasma membrane , 2012, Nature Cell Biology.

[3]  S. Grinstein,et al.  Phosphatidylserine dynamics in cellular membranes , 2012, Molecular biology of the cell.

[4]  V. Bankaitis,et al.  Golgi Membrane Dynamics and Lipid Metabolism , 2012, Current Biology.

[5]  T. Baumgart,et al.  Nonlinear sorting, curvature generation, and crowding of endophilin N-BAR on tubular membranes. , 2012, Biophysical journal.

[6]  Adam Frost,et al.  Structural Basis of Membrane Bending by the N-BAR Protein Endophilin , 2012, Cell.

[7]  A. Hinnebusch,et al.  A Sterol-Binding Protein Integrates Endosomal Lipid Metabolism with TOR Signaling and Nitrogen Sensing , 2012, Cell.

[8]  Xinchao Yu,et al.  A Structure-Based Mechanism for Arf1-Dependent Recruitment of Coatomer to Membranes , 2012, Cell.

[9]  G. Sakoulas,et al.  Reduced vancomycin susceptibility among clinical Staphylococcus aureus isolates (‘the MIC Creep’): implications for therapy , 2012, F1000 medicine reports.

[10]  C. Loewen Lipids as conductors in the orchestra of life , 2012, F1000 biology reports.

[11]  M. Setou,et al.  Axonal Gradient of Arachidonic Acid-containing Phosphatidylcholine and Its Dependence on Actin Dynamics* , 2011, The Journal of Biological Chemistry.

[12]  D. Bar-Sagi,et al.  Regulating the regulator: post-translational modification of RAS , 2011, Nature Reviews Molecular Cell Biology.

[13]  D. Douguet,et al.  Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers , 2011, The Journal of cell biology.

[14]  Sune M. Christensen,et al.  Intermembrane docking reactions are regulated by membrane curvature. , 2011, Biophysical journal.

[15]  O. Shupliakov,et al.  Synapsin I Senses Membrane Curvature by an Amphipathic Lipid Packing Sensor Motif , 2011, The Journal of Neuroscience.

[16]  Pietro De Camilli,et al.  Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission , 2011, Neuron.

[17]  T. Balla,et al.  A highly dynamic ER-derived phosphatidylinositol-synthesizing organelle supplies phosphoinositides to cellular membranes. , 2011, Developmental cell.

[18]  N. Mizushima,et al.  The role of Atg proteins in autophagosome formation. , 2011, Annual review of cell and developmental biology.

[19]  Robert V Farese,et al.  Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase. , 2011, Cell metabolism.

[20]  O. Jensen,et al.  WAVE regulatory complex activation by cooperating GTPases Arf and Rac1 , 2011, Proceedings of the National Academy of Sciences.

[21]  S. Grinstein,et al.  High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine , 2011, The Journal of cell biology.

[22]  B. Antonny,et al.  α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding , 2011, The Journal of cell biology.

[23]  Bruno Antonny,et al.  Mechanisms of membrane curvature sensing. , 2011, Annual review of biochemistry.

[24]  T. Meyer,et al.  STIM proteins and the endoplasmic reticulum-plasma membrane junctions. , 2011, Annual review of biochemistry.

[25]  C. Leslie,et al.  COPI acts in both vesicular and tubular transport , 2011, Nature Cell Biology.

[26]  Q. Zhong,et al.  Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L) , 2011, Proceedings of the National Academy of Sciences.

[27]  Lee H. Dicker,et al.  Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity , 2011, Nature.

[28]  G. Voth,et al.  Mechanism of membrane curvature sensing by amphipathic helix containing proteins. , 2011, Biophysical journal.

[29]  Thierry Ferreira,et al.  Modulation of Lipid‐Induced ER Stress by Fatty Acid Shape , 2011, Traffic.

[30]  R. Chan,et al.  Synaptojanin 1-mediated PI(4,5)P2 hydrolysis is modulated by membrane curvature and facilitates membrane fission. , 2011, Developmental cell.

[31]  J. Molotkovsky,et al.  The intermembrane ceramide transport catalyzed by CERT is sensitive to the lipid environment. , 2011, Biochimica et biophysica acta.

[32]  S. Lev Non-vesicular lipid transport by lipid-transfer proteins and beyond , 2010, Nature Reviews Molecular Cell Biology.

[33]  G. Carman,et al.  A phosphorylation-regulated amphipathic helix controls the membrane translocation and function of the yeast phosphatidate phosphatase , 2010, Proceedings of the National Academy of Sciences.

[34]  Johannes Buchner,et al.  Hsp12 is an intrinsically unstructured stress protein that folds upon membrane association and modulates membrane function. , 2010, Molecular cell.

[35]  S. Akira,et al.  Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L , 2010, The Journal of cell biology.

[36]  S. Munro,et al.  A Comprehensive Comparison of Transmembrane Domains Reveals Organelle-Specific Properties , 2010, Cell.

[37]  J. Prestegard,et al.  Dynamic structure of membrane-anchored Arf•GTP , 2010, Nature Structural &Molecular Biology.

[38]  P. Evans,et al.  A Large-Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the AP2 Clathrin Adaptor Complex , 2010, Cell.

[39]  S. Grinstein,et al.  The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole. , 2010, Cell host & microbe.

[40]  M. Hetzer,et al.  Cell Cycle-Dependent Differences in Nuclear Pore Complex Assembly in Metazoa , 2010, Cell.

[41]  J. Lippincott-Schwartz,et al.  Lipids and cholesterol as regulators of traffic in the endomembrane system. , 2010, Annual review of biophysics.

[42]  T. Kirchhausen,et al.  Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin–AP-1-coated carrier biogenesis at the TGN , 2010, Nature Cell Biology.

[43]  M. Glogauer,et al.  Pivotal Advance: Phospholipids determine net membrane surface charge resulting in differential localization of active Rac1 and Rac2 , 2010, Journal of leukocyte biology.

[44]  J. Rothman,et al.  Induction of cortical endoplasmic reticulum by dimerization of a coatomer-binding peptide anchored to endoplasmic reticulum membranes , 2010, Proceedings of the National Academy of Sciences.

[45]  P. Bassereau,et al.  Membrane curvature controls dynamin polymerization , 2010, Proceedings of the National Academy of Sciences.

[46]  Kai Simons,et al.  Lipid Rafts As a Membrane-Organizing Principle , 2010, Science.

[47]  R. Ghirlando,et al.  Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues , 2009, The Journal of cell biology.

[48]  W. Nickel,et al.  A Conserved, Lipid‐Mediated Sorting Mechanism of Yeast Ist2 and Mammalian STIM Proteins to the Peripheral ER , 2009, Traffic.

[49]  Yoko Shibata,et al.  Mechanisms shaping the membranes of cellular organelles. , 2009, Annual review of cell and developmental biology.

[50]  M. Bornens,et al.  Golgi localisation of GMAP210 requires two distinct cis-membrane binding mechanisms , 2009, BMC Biology.

[51]  W. Brown,et al.  Lysophosphatidic acid acyltransferase 3 regulates Golgi complex structure and function , 2009, The Journal of cell biology.

[52]  S. Grinstein,et al.  Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation , 2009, The Journal of cell biology.

[53]  Christer S. Ejsing,et al.  Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network , 2009, The Journal of cell biology.

[54]  M. Rudolph,et al.  TIP47 functions in the biogenesis of lipid droplets , 2009, The Journal of cell biology.

[55]  P. Camilli,et al.  The BAR Domain Superfamily: Membrane-Molding Macromolecules , 2009, Cell.

[56]  J. McDonald,et al.  Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance. , 2008, Cell metabolism.

[57]  Patricia Bassereau,et al.  COPI coat assembly occurs on liquid-disordered domains and the associated membrane deformations are limited by membrane tension , 2008, Proceedings of the National Academy of Sciences.

[58]  Bruno Antonny,et al.  Asymmetric Tethering of Flat and Curved Lipid Membranes by a Golgin , 2008, Science.

[59]  D. Cassel,et al.  Topology of Amphipathic Motifs Mediating Golgi Localization in ArfGAP1 and Its Splice Isoforms* , 2008, Journal of Biological Chemistry.

[60]  Y. Hannun,et al.  Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide , 2007, Nature.

[61]  B. Goud,et al.  Functional symmetry of endomembranes. , 2007, Molecular biology of the cell.

[62]  G. Drin,et al.  A general amphipathic α-helical motif for sensing membrane curvature , 2007, Nature Structural &Molecular Biology.

[63]  Pietro De Camilli,et al.  Phosphoinositides in cell regulation and membrane dynamics , 2006, Nature.

[64]  D. Brasaemle,et al.  A proposed model of fat packaging by exchangeable lipid droplet proteins , 2006, FEBS letters.

[65]  P. Janmey,et al.  Biophysical properties of lipids and dynamic membranes. , 2006, Trends in cell biology.

[66]  Mark Philips,et al.  Receptor Activation Alters Inner Surface Potential During Phagocytosis , 2006, Science.

[67]  T. Pomorski,et al.  Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles. , 2006, Molecular biology of the cell.

[68]  J. Silvius Partitioning of membrane molecules between raft and non-raft domains: insights from model-membrane studies. , 2005, Biochimica et biophysica acta.

[69]  S. Henry,et al.  Depletion of phosphatidylcholine in yeast induces shortening and increased saturation of the lipid acyl chains: evidence for regulation of intrinsic membrane curvature in a eukaryote. , 2005, Molecular biology of the cell.

[70]  James H. Hurley,et al.  Structural mechanism for sterol sensing and transport by OSBP-related proteins , 2005, Nature.

[71]  Randy Schekman,et al.  Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle , 2005, Cell.

[72]  S. Grinstein Faculty Opinions recommendation of Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome. , 2005 .

[73]  Toshihiro Kobayashi,et al.  Isoform-Specific Membrane Targeting Mechanism of Rac during FcγR-Mediated Phagocytosis: Positive Charge-Dependent and Independent Targeting Mechanism of Rac to the Phagosome1 , 2005, The Journal of Immunology.

[74]  G. Drin,et al.  ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif , 2005, The EMBO journal.

[75]  Herbert Waldmann,et al.  An Acylation Cycle Regulates Localization and Activity of Palmitoylated Ras Isoforms , 2005, Science.

[76]  J. Holthuis,et al.  Lipid traffic: floppy drives and a superhighway , 2005, Nature Reviews Molecular Cell Biology.

[77]  Wendell A Lim,et al.  A polybasic motif allows N-WASP to act as a sensor of PIP(2) density. , 2005, Molecular cell.

[78]  B. Antonny,et al.  A Phosphatidylserine-binding Site in the Cytosolic Fragment of Clostridium sordellii Lethal Toxin Facilitates Glucosylation of Membrane-bound Rac and Is Required for Cytotoxicity* , 2004, Journal of Biological Chemistry.

[79]  J. Killian,et al.  Nonbilayer lipids affect peripheral and integral membrane proteins via changes in the lateral pressure profile. , 2004, Biochimica et biophysica acta.

[80]  J. Bonifacino,et al.  The Mechanisms of Vesicle Budding and Fusion , 2004, Cell.

[81]  B. Peter,et al.  BAR Domains as Sensors of Membrane Curvature: The Amphiphysin BAR Structure , 2004, Science.

[82]  Satoshi Yasuda,et al.  Molecular machinery for non-vesicular trafficking of ceramide , 2003, Nature.

[83]  Bruno Antonny,et al.  Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature , 2003, Nature.

[84]  M. Roth,et al.  Phosphatidylinositol 4 Phosphate Regulates Targeting of Clathrin Adaptor AP-1 Complexes to the Golgi , 2003, Cell.

[85]  T. Graham,et al.  An essential subfamily of Drs2p-related P-type ATPases is required for protein trafficking between Golgi complex and endosomal/vacuolar system. , 2002, Molecular biology of the cell.

[86]  I. Wilson,et al.  Crystal structure of Sar1-GDP at 1.7 Å resolution and the role of the NH2 terminus in ER export , 2001, The Journal of cell biology.

[87]  G. von Heijne,et al.  Inhibition of Protein Translocation across the Endoplasmic Reticulum Membrane by Sterols* , 2001, The Journal of Biological Chemistry.

[88]  R. Epand,et al.  Regulation of CTP: phosphocholine cytidylyltransferase activity by the physical properties of lipid membranes: an important role for stored curvature strain energy. , 2001, Biochemistry.

[89]  W. Lehmann,et al.  Evidence for Segregation of Sphingomyelin and Cholesterol during Formation of Copi-Coated Vesicles , 2000, The Journal of cell biology.

[90]  R. Templer,et al.  Modulation of CTP:phosphocholine cytidylyltransferase by membrane curvature elastic stress. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[91]  R. Leventis,et al.  Mutational and biochemical analysis of plasma membrane targeting mediated by the farnesylated, polybasic carboxy terminus of K-ras4B. , 2000, Biochemistry.

[92]  G. Daum,et al.  Lipid composition of subcellular membranes of an FY1679‐derived haploid yeast wild‐type strain grown on different carbon sources , 1999, Yeast.

[93]  R. Schneiter,et al.  Electrospray Ionization Tandem Mass Spectrometry (Esi-Ms/Ms) Analysis of the Lipid Molecular Species Composition of Yeast Subcellular Membranes Reveals Acyl Chain-Based Sorting/Remodeling of Distinct Molecular Species En Route to the Plasma Membrane , 1999, The Journal of cell biology.

[94]  R. Schekman,et al.  COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes , 1998, Cell.

[95]  B. Antonny,et al.  Activation of ADP-ribosylation Factor 1 GTPase-Activating Protein by Phosphatidylcholine-derived Diacylglycerols* , 1997, The Journal of Biological Chemistry.

[96]  A. Aderem,et al.  The myristoyl-electrostatic switch: a modulator of reversible protein-membrane interactions. , 1995, Trends in biochemical sciences.

[97]  J. Silvius,et al.  Doubly-lipid-modified protein sequence motifs exhibit long-lived anchorage to lipid bilayer membranes. , 1995, Biochemistry.

[98]  M. Bretscher,et al.  Cholesterol and the Golgi apparatus. , 1993, Science.

[99]  J. Molotkovsky,et al.  The intermembrane ceramide transport catalyzed by CERT is sensitive to the lipid environment. , 2011, Biochimica et biophysica acta.

[100]  Belle Chang The Hydrolysis of PI(4,5)P2 by the Synaptojanin-Endophilin Partnership Is Modulated by Membrane Curvature and Facilitates Membrane Fission , 2011 .