Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway

[1]  N. Ahmad,et al.  Targeted knockdown of polo-like kinase 1 alters metabolic regulation in melanoma. , 2017, Cancer letters.

[2]  C. Thompson,et al.  The Emerging Hallmarks of Cancer Metabolism. , 2016, Cell metabolism.

[3]  Rosanne Raso,et al.  Changing a paradigm. , 2015, Nursing management.

[4]  M. Mandal,et al.  BI2536--A PLK inhibitor augments paclitaxel efficacy in suppressing tamoxifen induced senescence and resistance in breast cancer cells. , 2015, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[5]  Libing Song,et al.  cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions , 2015, Cell Research.

[6]  S. Kuang,et al.  Inhibition of Polo-like Kinase 1 (Plk1) Enhances the Antineoplastic Activity of Metformin in Prostate Cancer* , 2014, The Journal of Biological Chemistry.

[7]  Huafeng Zhang,et al.  Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1 , 2014, Nature Communications.

[8]  G. Semenza,et al.  HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression. , 2014, Cell reports.

[9]  N. Hay,et al.  The pentose phosphate pathway and cancer. , 2014, Trends in biochemical sciences.

[10]  J. Li,et al.  Plk1 Phosphorylation of PTEN Causes a Tumor-Promoting Metabolic State , 2014, Molecular and Cellular Biology.

[11]  P. Jiang,et al.  Regulation of the pentose phosphate pathway in cancer , 2014, Protein & Cell.

[12]  Hongzhuan Yin,et al.  High Expression of Polo-Like Kinase 1 Is Associated with Early Development of Hepatocellular Carcinoma , 2014, International journal of genomics.

[13]  D. Glover,et al.  Inhibition of Polo kinase by BI2536 affects centriole separation during Drosophila male meiosis , 2014, Cell cycle.

[14]  P. Puigserver,et al.  Cyclin D1-CDK4 Controls Glucose Metabolism Independently of Cell Cycle Progression , 2014, Nature.

[15]  J. Blenis,et al.  Estradiol promotes pentose phosphate pathway addiction and cell survival via reactivation of Akt in mTORC1 hyperactive cells , 2014, Cell Death and Disease.

[16]  F. He,et al.  Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progression. , 2014, Developmental cell.

[17]  G. E. Atilla‐Gokcumen,et al.  Dividing Cells Regulate Their Lipid Composition and Localization , 2014, Cell.

[18]  In Hye Lee,et al.  Metabolic regulation of the cell cycle. , 2013, Current opinion in cell biology.

[19]  Guojun Zhang,et al.  High expression of polo-like kinase 1 is associated with the metastasis and recurrence in urothelial carcinoma of bladder. , 2013, Urologic oncology.

[20]  T. Mak,et al.  TAp73 enhances the pentose phosphate pathway and supports cell proliferation , 2013, Nature Cell Biology.

[21]  B. Tu,et al.  Driving the cell cycle through metabolism. , 2012, Annual review of cell and developmental biology.

[22]  H. Aburatani,et al.  Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. , 2012, Cancer cell.

[23]  Gerald C. Chu,et al.  Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism , 2012, Cell.

[24]  Xiaoqi Liu,et al.  Polo-like kinase 1 (Plk1): an Unexpected Player in DNA Replication , 2012, Cell Division.

[25]  S. Moncada,et al.  Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells , 2011, Proceedings of the National Academy of Sciences.

[26]  Xiaoqi Liu,et al.  Plk1 Phosphorylation of Orc2 Promotes DNA Replication under Conditions of Stress , 2011, Molecular and Cellular Biology.

[27]  A. Mancuso,et al.  p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase , 2011, Nature Cell Biology.

[28]  Xiaoqi Liu,et al.  The substrates of Plk1, beyond the functions in mitosis , 2010, Protein & Cell.

[29]  K. Strebhardt,et al.  Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy , 2010, Nature Reviews Drug Discovery.

[30]  Qicheng Ma,et al.  Activation of a metabolic gene regulatory network downstream of mTOR complex 1. , 2010, Molecular cell.

[31]  S. Moncada,et al.  E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation , 2009, Proceedings of the National Academy of Sciences.

[32]  P. Engel,et al.  Clinical mutants of human glucose 6-phosphate dehydrogenase: impairment of NADP(+) binding affects both folding and stability. , 2009, Biochimica et biophysica acta.

[33]  L. Cantley,et al.  Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation , 2009, Science.

[34]  M. Barbacid,et al.  Cell cycle, CDKs and cancer: a changing paradigm , 2009, Nature Reviews Cancer.

[35]  Hao Li,et al.  Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression , 2008, Nature Cell Biology.

[36]  Péter Lénárt,et al.  Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1. , 2008, Developmental cell.

[37]  T. Furuya,et al.  Overexpression of Polo-Like Kinase 1 (PLK1) and Chromosomal Instability in Bladder Cancer , 2006, Oncology.

[38]  A. Ullrich,et al.  Targeting polo-like kinase 1 for cancer therapy , 2006, Nature Reviews Cancer.

[39]  Russell G. Jones,et al.  AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. , 2005, Molecular cell.

[40]  Jun Yoshimatsu,et al.  Polo-like kinases (Plks) and cancer , 2005, Oncogene.

[41]  A. Sancar,et al.  Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. , 2004, Annual review of biochemistry.

[42]  Michael B. Yaffe,et al.  The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain , 2003, Cell.

[43]  Michael B Yaffe,et al.  Proteomic Screen Finds pSer/pThr-Binding Domain Localizing Plk1 to Mitotic Substrates , 2003, Science.

[44]  Takao Takahashi,et al.  Polo‐like kinase 1 (PLK1) is overexpressed in primary colorectal cancers , 2003, Cancer science.

[45]  S. Au,et al.  Human glucose-6-phosphate dehydrogenase: the crystal structure reveals a structural NADP(+) molecule and provides insights into enzyme deficiency. , 2000, Structure.

[46]  N. J. Wells,et al.  Physiological regulation of eukaryotic topoisomerase II. , 1998, Biochimica et biophysica acta.

[47]  D. Longo,et al.  Malignant transformation of mammalian cells initiated by constitutive expression of the polo-like kinase. , 1997, Biochemical and biophysical research communications.

[48]  P. Nurse Universal control mechanism regulating onset of M-phase , 1990, Nature.

[49]  T. Hunt Under arrest in the cell cycle , 1989, Nature.

[50]  L. Hartwell,et al.  Checkpoints: controls that ensure the order of cell cycle events. , 1989, Science.

[51]  L. Luzzatto,et al.  Genetic variants of human erythrocyte glucose-6-phosphate dehydrogenase. Kinetic and thermodynamic parameters of variants A, B, and A- in relation to quaternary structure. , 1976, The Journal of biological chemistry.

[52]  M. Rosemeyer,et al.  Human glucose-6-phosphate dehydrogenase: purification of the erythrocyte enzyme and the influence of ions on its activity. , 1969, European journal of biochemistry.

[53]  O. Warburg On the origin of cancer cells. , 1956, Science.

[54]  M. Malumbres,et al.  Fueling the Cell Division Cycle. , 2017, Trends in cell biology.

[55]  R. Deberardinis,et al.  The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. , 2008, Cell metabolism.

[56]  T. Hunt Embryology. Under arrest in the cell cycle. , 1989, Nature.