Implications from proteomic studies investigating circadian rhythm disorder-regulated neurodegenerative disease pathology.

[1]  M. Kjaer,et al.  Disruption of day-to-night changes in circadian gene expression with chronic tendinopathy. , 2023, The Journal of physiology.

[2]  H. Zimmermann,et al.  Multiple sclerosis and circadian rhythms: Can diet act as a treatment? , 2023, Acta physiologica.

[3]  Lin Chen,et al.  Endothelin-1, over-expressed in SOD1G93A mice, aggravates injury of NSC34-hSOD1G93A cells through complicated molecular mechanism revealed by quantitative proteomics analysis , 2022, Frontiers in Cellular Neuroscience.

[4]  R. Cao,et al.  The trilateral interactions between mammalian target of rapamycin (mTOR) signaling, the circadian clock, and psychiatric disorders: an emerging model , 2022, Translational Psychiatry.

[5]  N. Xiong,et al.  The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson’s disease via the microglial NLRP3 inflammasome , 2022, Journal of neuroinflammation.

[6]  K. Merchant,et al.  Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson’s disease , 2022, Cell reports. Medicine.

[7]  A. Brunner,et al.  Deep Visual Proteomics defines single-cell identity and heterogeneity , 2022, Nature Biotechnology.

[8]  K. Hoyt,et al.  Circadian clocks, cognition, and Alzheimer’s disease: synaptic mechanisms, signaling effectors, and chronotherapeutics , 2022, Molecular neurodegeneration.

[9]  Y. Qi,et al.  Label-free Quantitative Proteomic Analysis of Cerebrospinal Fluid and Serum in Patients With Relapse-Remitting Multiple Sclerosis , 2022, Frontiers in Genetics.

[10]  David S. Fischer,et al.  Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation , 2022, Molecular systems biology.

[11]  C. McClung,et al.  Astrocyte Molecular Clock Function in the Nucleus Accumbens Is Important for Reward-Related Behavior , 2022, Biological Psychiatry.

[12]  A. Alexiou,et al.  Roles of clock genes in the pathogenesis of Parkinson's disease , 2021, Ageing Research Reviews.

[13]  J. Devaud,et al.  Dynamically expressed single ELAV/Hu orthologue elavl2 of bees is required for learning and memory , 2021, Communications biology.

[14]  C. Colwell Defining circadian disruption in neurodegenerative disorders. , 2021, The Journal of clinical investigation.

[15]  Xiaoling Zhao,et al.  A transcriptome analysis for 24-hour continuous sampled uterus reveals circadian regulation of the key pathways involved in eggshell formation of chicken , 2021, Poultry science.

[16]  H. Harbo,et al.  Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls , 2021, Clinical Proteomics.

[17]  M. Figiel,et al.  Juvenile Huntington’s Disease and Other PolyQ Diseases, Update on Neurodevelopmental Character and Comparative Bioinformatic Review of Transcriptomic and Proteomic Data , 2021, Frontiers in Cell and Developmental Biology.

[18]  Sheng-Xi Wu,et al.  Extracellular matrix protein laminin β1 regulates pain sensitivity and anxiodepression-like behaviors in mice. , 2021, The Journal of clinical investigation.

[19]  S. Lehmann,et al.  NFL strongly correlates with TNF-R1 in the plasma of AD patients, but not with cognitive decline , 2021, Scientific Reports.

[20]  E. Kılıç,et al.  The role of circadian rhythm in the regulation of cellular protein profiles in the brain. , 2020, Turkish journal of medical sciences.

[21]  R. Barker,et al.  The sleep and circadian problems of Huntington’s disease: when, why and their importance , 2020, Journal of Neurology.

[22]  A. Kalsbeek,et al.  Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism , 2020, Frontiers in Immunology.

[23]  R. H. Khan,et al.  Review on Alzheimer's disease: Inhibition of amyloid beta and tau tangle formation. , 2020, International journal of biological macromolecules.

[24]  E. Musiek,et al.  REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis , 2020, eLife.

[25]  Surendhar Reddy Chepyala,et al.  Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer’s disease , 2020, Molecular Neurodegeneration.

[26]  Fuquan Zhang,et al.  Multi-trait analysis for genome-wide association study of five psychiatric disorders , 2020, Translational Psychiatry.

[27]  Maximilian T. Strauss,et al.  Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease , 2020, Molecular systems biology.

[28]  Yu Xue,et al.  Integrated omics in Drosophila uncover a circadian kinome , 2020, Nature Communications.

[29]  R. Bateman,et al.  Increased Cerebrospinal Fluid Amyloid-β During Sleep Deprivation in Healthy Middle-Aged Adults Is Not Due to Stress or Circadian Disruption. , 2020, Journal of Alzheimer's disease : JAD.

[30]  D. Figeys,et al.  Aging Disrupts the Circadian Patterns of Protein Expression in the Murine Hippocampus , 2020, Frontiers in Aging Neuroscience.

[31]  F. Gachon,et al.  Proteomics in circadian biology. , 2019, Journal of molecular biology.

[32]  Steven A. Brown,et al.  The forebrain synaptic transcriptome is organized by clocks but its proteome is driven by sleep , 2019, Science.

[33]  Steven A. Brown,et al.  Sleep-wake cycles drive daily dynamics of synaptic phosphorylation , 2019, Science.

[34]  M. Larsen,et al.  Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation , 2019, Neurobiology of Disease.

[35]  D. Figeys,et al.  Therapeutic targeting of casein kinase 1δ/ε in an Alzheimer's disease mouse model. , 2019, Journal of proteome research.

[36]  T. Kubo,et al.  REV-ERBα and REV-ERBβ function as key factors regulating Mammalian Circadian Output , 2019, Scientific Reports.

[37]  Yuan Wang,et al.  Effects of chronic cocaine exposure on the circadian rhythmic expression of the clock genes in reward-related brain areas in rats , 2019, Behavioural Brain Research.

[38]  Rebecca Kelsey Increased α-synuclein levels in patients with sleep apnoea might be involved in PD pathogenesis , 2019, Nature Reviews Neurology.

[39]  F. Bertile,et al.  Circadian Analysis of the Mouse Cerebellum Proteome , 2019, International journal of molecular sciences.

[40]  Y. Baek,et al.  Association between digestive symptoms and sleep disturbance: a cross-sectional community-based study , 2019, BMC Gastroenterology.

[41]  J. Chiu,et al.  CK1α Collaborates with DOUBLETIME to Regulate PERIOD Function in the Drosophila Circadian Clock , 2018, The Journal of Neuroscience.

[42]  Y. Mechref,et al.  Novel biomarker signatures for idiopathic REM sleep behavior disorder , 2018, Neurology.

[43]  N. Slavov,et al.  SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation , 2017, Genome Biology.

[44]  J. Wojcik,et al.  Alzheimer disease pathology and the cerebrospinal fluid proteome , 2018, Alzheimer's Research & Therapy.

[45]  Kazuto Kobayashi,et al.  Human tyrosine hydroxylase in Parkinson’s disease and in related disorders , 2018, Journal of Neural Transmission.

[46]  O. Onaolapo,et al.  Melatonin in drug addiction and addiction management: Exploring an evolving multidimensional relationship , 2018, World journal of psychiatry.

[47]  A. Relógio,et al.  A Systems-Level Analysis Reveals Circadian Regulation of Splicing in Colorectal Cancer , 2018, EBioMedicine.

[48]  M. Yanagisawa,et al.  Quantitative phosphoproteomic analysis of the molecular substrates of sleep need , 2018, Nature.

[49]  P. Moreira,et al.  Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington’s Disease , 2018, Scientific Reports.

[50]  E. Melanson,et al.  Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome , 2018, Proceedings of the National Academy of Sciences.

[51]  M. L. Nielsen,et al.  Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism. , 2018, Cell reports.

[52]  David M Holtzman,et al.  Circadian Rest-Activity Pattern Changes in Aging and Preclinical Alzheimer Disease , 2018, JAMA neurology.

[53]  Weineng Chen,et al.  Circadian Rhythm Dysfunction Accelerates Disease Progression in a Mouse Model With Amyotrophic Lateral Sclerosis , 2018, Front. Neurol..

[54]  Fen Wang,et al.  Disruption of the Circadian Clock Alters Antioxidative Defense via the SIRT1-BMAL1 Pathway in 6-OHDA-Induced Models of Parkinson's Disease , 2018, Oxidative medicine and cellular longevity.

[55]  D. Holtzman,et al.  Regulation of amyloid-β dynamics and pathology by the circadian clock , 2018, The Journal of experimental medicine.

[56]  C. Saper,et al.  A hypothalamic circuit for the circadian control of aggression , 2018, Nature Neuroscience.

[57]  N. Zisapel New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation , 2018, British journal of pharmacology.

[58]  Hua Zhu,et al.  Effective expression of Drebrin in hippocampus improves cognitive function and alleviates lesions of Alzheimer's disease in APP (swe)/PS1 (ΔE9) mice , 2017, CNS neuroscience & therapeutics.

[59]  Prashant Mishra,et al.  Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor , 2017, Cell.

[60]  H. Naito,et al.  Circadian rhythm of intracellular protein synthesis signaling in rat cardiac and skeletal muscles , 2016, Biochemistry and biophysics reports.

[61]  O. Rawashdeh,et al.  Period1 gates the circadian modulation of memory‐relevant signaling in mouse hippocampus by regulating the nuclear shuttling of the CREB kinase pP90RSK , 2016, Journal of neurochemistry.

[62]  Joanna Mattis,et al.  Circadian Rhythms, Sleep, and Disorders of Aging , 2016, Trends in Endocrinology & Metabolism.

[63]  M. Mann,et al.  Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins , 2016, Proceedings of the National Academy of Sciences.

[64]  Matthias Mann,et al.  Cell type– and brain region–resolved mouse brain proteome , 2015, Nature Neuroscience.

[65]  T. Conrads,et al.  Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis. , 2015, Journal of proteome research.

[66]  S. Maret,et al.  In Vivo Imaging of the Central and Peripheral Effects of Sleep Deprivation and Suprachiasmatic Nuclei Lesion on PERIOD-2 Protein in Mice. , 2015, Sleep.

[67]  S. Lazic,et al.  Sleep deficits but no metabolic deficits in premanifest Huntington's disease , 2015, Annals of neurology.

[68]  C. von Gall,et al.  Premature aging of the hippocampal neurogenic niche in adult Bmal1‐ deficient mice , 2015, Aging.

[69]  R. Roos,et al.  Hypothalamic‐Pituitary‐Adrenal Axis Functioning in Huntington's Disease and its Association with Depressive Symptoms and Suicidality , 2015, Journal of neuroendocrinology.

[70]  U. Schmidt,et al.  Proteomics of Huntington's disease-affected human embryonic stem cells reveals an evolving pathology involving mitochondrial dysfunction and metabolic disturbances. , 2014, Journal of proteome research.

[71]  W. Pan,et al.  Sleep Restriction Impairs Blood–Brain Barrier Function , 2014, The Journal of Neuroscience.

[72]  M. Hughes,et al.  A circadian gene expression atlas in mammals: Implications for biology and medicine , 2014, Proceedings of the National Academy of Sciences.

[73]  Thomas E. Nichols,et al.  Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease , 2014, BMC Genomics.

[74]  Zhibin Ning,et al.  The Proteomic Landscape of the Suprachiasmatic Nucleus Clock Reveals Large-Scale Coordination of Key Biological Processes , 2014, PLoS genetics.

[75]  S. Lesage,et al.  Synaptojanin 1 Mutation in Parkinson's Disease Brings Further Insight into the Neuropathological Mechanisms , 2014, BioMed research international.

[76]  D. Holtzman,et al.  Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration. , 2013, The Journal of clinical investigation.

[77]  Mads Kærn,et al.  The circadian molecular clock regulates adult hippocampal neurogenesis by controlling the timing of cell-cycle entry and exit. , 2013, Cell reports.

[78]  F. Jackson,et al.  Translational Profiling of Clock Cells Reveals Circadianly Synchronized Protein Synthesis , 2013, PLoS biology.

[79]  Takao Miki,et al.  p53 Regulates Period2 Expression and the Circadian Clock , 2013, Nature Communications.

[80]  Chadwick M. Hales,et al.  U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease , 2013, Proceedings of the National Academy of Sciences.

[81]  D. Bennett,et al.  Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons. , 2013, Sleep.

[82]  Adam W. Bero,et al.  Disruption of the Sleep-Wake Cycle and Diurnal Fluctuation of β-Amyloid in Mice with Alzheimer’s Disease Pathology , 2012, Science Translational Medicine.

[83]  P. Franken,et al.  Sleep Loss Reduces the DNA-Binding of BMAL1, CLOCK, and NPAS2 to Specific Clock Genes in the Mouse Cerebral Cortex , 2011, PloS one.

[84]  M. Passafaro,et al.  A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα , 2011, Nature Neuroscience.

[85]  Joseph S. Takahashi,et al.  Circadian Integration of Metabolism and Energetics , 2010, Science.

[86]  M. Antoch,et al.  Circadian clock proteins control adaptation to novel environment and memory formation , 2010, Aging.

[87]  Daniel A. Cohen,et al.  Uncovering Residual Effects of Chronic Sleep Loss on Human Performance , 2010, Science Translational Medicine.

[88]  B. Peterlin,et al.  Autonomic dysfunction in presymptomatic and early symptomatic Huntington’s disease , 2009, Acta neurologica Scandinavica.

[89]  Angelo Antonini,et al.  The PRIAMO study: A multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease , 2009, Movement disorders : official journal of the Movement Disorder Society.

[90]  J. Cordes,et al.  Cardiovagal modulation upon postural change is altered in Huntington’s disease , 2008, European journal of neurology.

[91]  Gudrun Ahnert-Hilger,et al.  Regulation of Monoamine Oxidase A by Circadian-Clock Components Implies Clock Influence on Mood , 2008, Current Biology.

[92]  T. Hirota,et al.  Circadian proteomics of the mouse retina , 2007, Proteomics.

[93]  M. Straume,et al.  Disturbed Diurnal Rhythm Alters Gene Expression and Exacerbates Cardiovascular Disease With Rescue by Resynchronization , 2007, Hypertension.

[94]  Barbara A. Sorg,et al.  Diurnal differences in dopamine transporter and tyrosine hydroxylase levels in rat brain: Dependence on the suprachiasmatic nucleus , 2007, Brain Research.

[95]  Kazuto Kobayashi,et al.  Molecular genetics of tyrosine 3-monooxygenase and inherited diseases. , 2005, Biochemical and biophysical research communications.

[96]  B. Peterlin,et al.  Early sympathetic hyperactivity in Huntington's disease , 2004, European journal of neurology.

[97]  Junmin Peng,et al.  Proteomic Characterization of Postmortem Amyloid Plaques Isolated by Laser Capture Microdissection*[boxs] , 2004, Journal of Biological Chemistry.

[98]  R J Konopka,et al.  Clock mutants of Drosophila melanogaster. , 1971, Proceedings of the National Academy of Sciences of the United States of America.