Efficient magnetic localization and orientation technique for capsule endoscopy

To build a new wireless robotic capsule endoscope with external guidance for controllable and interactive GI tract examination, a sensing system is needed for tracking 3D location and 2D orientation of the capsule movement. An appropriate sensing approach is to enclose a small permanent magnet in the capsule. The magnet establishes a magnetic field around the patient's body. With the sensing data of magnetic sensor array outside the patient's body, the 3D location and 2D orientation of the capsule can be calculated. Higher localization and orientation accuracy can be obtained if more sensors and proper optimization algorithm are applied. In this paper, different nonlinear optimization algorithms are evaluated, and we have found that Levenberg-Marquardt method provides higher accuracy and faster speed. Simulations were done for investigating the de-noise ability of this algorithm based on different sensor arrays. Furthermore, the real experiment shows that the results are satisfactory with high accuracy.

[1]  P.-A. Besse,et al.  Tracking system with five degrees of freedom using a 2D-array of Hall sensors and a permanent magnet , 2001 .

[2]  Yongmin Kim,et al.  Interactive 3D registration of ultrasound and magnetic resonance images based on a magnetic position sensor , 1999, IEEE Transactions on Information Technology in Biomedicine.

[3]  D. Fischer,et al.  Capsule endoscopy: the localization system. , 2004, Gastrointestinal endoscopy clinics of North America.

[4]  D. Marquardt An Algorithm for Least-Squares Estimation of Nonlinear Parameters , 1963 .

[5]  G. Iddan,et al.  Wireless capsule endoscopy , 2003, Gut.

[6]  F. A. Seiler,et al.  Numerical Recipes in C: The Art of Scientific Computing , 1989 .

[7]  C. Swain,et al.  The Wireless Capsule: New Light in the Darkness , 2002, Digestive Diseases.

[8]  Tao Mei,et al.  Wireless robotic capsule endoscopy: state-of-the-art and challenges , 2004, Fifth World Congress on Intelligent Control and Automation (IEEE Cat. No.04EX788).

[9]  G. Iddan,et al.  History and development of capsule endoscopy. , 2004, Gastrointestinal endoscopy clinics of North America.

[10]  D. Leotta,et al.  Performance of a miniature magnetic position sensor for three-dimensional ultrasound imaging. , 1997, Ultrasound in medicine & biology.

[11]  Masatake Akutagawa,et al.  Application of neural networks to a magnetic measurement system for mandibular movement , 1998, Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286).

[12]  D. Cheng Field and wave electromagnetics , 1983 .

[13]  N. Yoshida,et al.  An application of magnet and magnetic sensor: measurement system for tooth movement , 1990, IEEE Transactions on Biomedical Engineering.

[14]  A. Glukhovsky,et al.  Future of capsule endoscopy. , 2004, Gastrointestinal endoscopy clinics of North America.

[15]  Kenneth Holmström,et al.  Global Optimization Using the DIRECT Algorithm in Matlab , 1999 .

[16]  F. Spelman,et al.  Localization of a magnetic marker for GI motility studies: an in vitro feasibility study , 1997, Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136).

[17]  I. Sasada,et al.  A new method for magnetic position and orientation tracking , 2001 .

[18]  Arnold Neumaier,et al.  Global Optimization by Multilevel Coordinate Search , 1999, J. Glob. Optim..

[19]  F. Raab,et al.  Magnetic Position and Orientation Tracking System , 1979, IEEE Transactions on Aerospace and Electronic Systems.

[20]  L. Trahms,et al.  Magnetic markers as a noninvasive tool to monitor gastrointestinal transit , 1994, IEEE Transactions on Biomedical Engineering.

[21]  K. Arai,et al.  Fabrication of magnetic actuator for use in a capsule endoscope , 2003 .