A symptom‐based model to predict colorectal cancer in low‐resource countries: Results from a prospective study of patients at high risk for colorectal cancer

Colorectal cancer (CRC) rates in low‐resource countries, which typically lack CRC screening programs, are rising. This study determined whether a risk model for patients with rectal bleeding could identify patients with curable CRC.

[1]  C. Ko,et al.  Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging. , 2005, Journal of the National Cancer Institute.

[2]  D. McMillan,et al.  Temporal trends in mode, site and stage of presentation with the introduction of colorectal cancer screening: a decade of experience from the West of Scotland , 2015, British Journal of Cancer.

[3]  Richard D Neal,et al.  The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review. , 2011, The British journal of general practice : the journal of the Royal College of General Practitioners.

[4]  T. Kingham,et al.  Health-Seeking Behavior and Barriers to Care in Patients With Rectal Bleeding in Nigeria , 2017, Journal of global oncology.

[5]  C. Nwokoro,et al.  Rectal bleeding amongst Medical Students: Prevalence and Consultation Behaviour. , 2011 .

[6]  O. Alatise,et al.  Spectrum of colonoscopy findings in Ile-Ife Nigeria. , 2012, The Nigerian postgraduate medical journal.

[7]  J. Hippisley-Cox,et al.  Identifying patients with suspected colorectal cancer in primary care: derivation and validation of an algorithm. , 2012, The British journal of general practice : the journal of the Royal College of General Practitioners.

[8]  R. Perera,et al.  Predictive value of common symptom combinations in diagnosing colorectal cancer , 2007, The British journal of surgery.

[9]  Y. Bafandeh,et al.  Clinical predictors of colorectal polyps and carcinoma in a low prevalence region: results of a colonoscopy based study. , 2008, World journal of gastroenterology.

[10]  J. Hardcastle,et al.  Colorectal cancer , 1993, Europe Against Cancer European Commission Series for General Practitioners.

[11]  Rui Feng,et al.  Diagnostic value of rectal bleeding in predicting colorectal cancer: a systematic review. , 2014, Asian Pacific journal of cancer prevention : APJCP.

[12]  J. B. Simon.  Diagnosis and management of colorectal cancer. , 1986, Comprehensive therapy.

[13]  M. Cowie.  National Institute for Health and Care Excellence. , 2015, European heart journal.

[14]  G. Falk,et al.  Diagnostic accuracy systematic review of rectal bleeding in combination with other symptoms, signs and tests in relation to colorectal cancer , 2009, British Journal of Cancer.

[15]  R. Baltussen,et al.  Cost effectiveness of strategies to combat breast, cervical, and colorectal cancer in sub-Saharan Africa and South East Asia: mathematical modelling study , 2012, BMJ : British Medical Journal.

[16]  K. Flashman,et al.  Is earlier referral and investigation of bowel cancer patients presenting with rectal bleeding associated with better survival? , 2011, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[17]  Sergio L. Schmukler,et al.  Emerging Market Instability : Do Sovereign Ratings Affect Country Risk and Stock Returns ? , 1997 .

[18]  A. Schoepfer,et al.  Colonoscopic findings of symptomatic patients aged 50 to 80 years suggest that work-up of tumour suspicious symptoms hardly reduces cancer-induced mortality. , 2005, Swiss medical weekly.

[19]  R. Enns,et al.  Incomplete colonoscopy: maximizing completion rates of gastroenterologists. , 2012, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

[20]  Douglas K. Rex,et al.  Quality Indicators for Colonoscopy , 2006, Gastrointestinal endoscopy.

[21]  Roger H Jones,et al.  Rectal bleeding: prevalence and consultation behaviour , 1995, BMJ.

[22]  J. Trojan,et al.  Prevalence of colorectal cancer and its precursor lesions in symptomatic and asymptomatic patients undergoing total colonoscopy: results of a large prospective, multicenter, controlled endoscopy study , 2013, European journal of gastroenterology & hepatology.

[23]  T. Sriprayoon,et al.  High prevalence of advanced colorectal neoplasia in the Thai population: a prospective screening colonoscopy of 1,404 cases , 2016, BMC Gastroenterology.

[24]  J. Coebergh,et al.  Recent trends in cancer survival across Europe between 2000 and 2004: a model-based period analysis from 12 cancer registries. , 2008, European journal of cancer.

[25]  Rinku Sutradhar,et al.  Analysis of administrative data finds endoscopist quality measures associated with postcolonoscopy colorectal cancer. , 2011, Gastroenterology.

[26]  O. Olopade,et al.  Treatment of cancer in sub-Saharan Africa. , 2013, The Lancet. Oncology.

[27]  Jie He,et al.  Expenditure and financial burden for common cancers in China: a hospital-based multicentre cross-sectional study , 2016, The Lancet.

[28]  W. Hamilton,et al.  Alarm features of colorectal cancer. , 2009, Gut.

[29]  Ahmedin Jemal,et al.  Global patterns and trends in colorectal cancer incidence and mortality , 2016, Gut.

[30]  Ahmedin Jemal,et al.  Global Cancer Incidence and Mortality Rates and Trends—An Update , 2015, Cancer Epidemiology, Biomarkers & Prevention.

[31]  J. Sung,et al.  Colorectal neoplasia in Asia: a multicenter colonoscopy survey in symptomatic patients. , 2006, Gastrointestinal endoscopy.

[32]  Thompson,et al.  Rectal bleeding in general and hospital practice; ‘the tip of the iceberg’ , 2000, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[33]  M. Gonen,et al.  A comparison of colorectal cancer in Nigerian and North American patients: is the cancer biology different? , 2014, Surgery.

[34]  Iris Lansdorp-Vogelaar,et al.  Cost-Effectiveness of CT Colonography to Screen for Colorectal Cancer , 2009 .

[35]  Aung Ko Win,et al.  Risk Prediction Models for Colorectal Cancer: A Systematic Review , 2015, Cancer Prevention Research.

[36]  Henrik Stovring,et al.  Proton Pump Inhibitor or Testing for Helicobacter pylori as the First Step for Patients Presenting with Dyspepsia? A Cluster-Randomized Trial , 2006, The American Journal of Gastroenterology.

[37]  W. Hamilton,et al.  Evaluation of risk assessment tools for suspected cancer in general practice: a cohort study. , 2013, The British journal of general practice : the journal of the Royal College of General Practitioners.

[38]  M. Keane,et al.  Early diagnosis improves survival in colorectal cancer. , 2012, The Practitioner.