Modulation of Human Recombinant GABAA Receptors by Pregnanediols

[1]  J. A. Peters,et al.  Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes , 1996, British journal of pharmacology.

[2]  J. A. Peters,et al.  Neurosteroids and GABAA receptor function. , 1995, Trends in pharmacological sciences.

[3]  W. Sieghart,et al.  Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes. , 1995, Pharmacological reviews.

[4]  R. Olsen,et al.  Functional domains of GABAA receptors. , 1995, Trends in pharmacological sciences.

[5]  P. Seeburg,et al.  GABAA/Benzodiazepine receptor heterogeneity: Neurophysiological implications , 1995, Neuropharmacology.

[6]  K. Gee,et al.  Selective actions of certain neuroactive pregnanediols at the gamma-aminobutyric acid type A receptor complex in rat brain. , 1995, Molecular pharmacology.

[7]  K. Gee,et al.  A putative receptor for neurosteroids on the GABAA receptor complex: the pharmacological properties and therapeutic potential of epalons. , 1995, Critical reviews in neurobiology.

[8]  R. Mckernan,et al.  Structure and pharmacology of vertebrate GABAA receptor subtypes. , 1995, International review of neurobiology.

[9]  J. Lambert,et al.  Correlation of neuroactive steroid modulation of [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding and gamma-aminobutyric acidA receptor function. , 1994, Molecular pharmacology.

[10]  M. Rogawski,et al.  Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation. , 1994, The Journal of pharmacology and experimental therapeutics.

[11]  Sheryl S. Smith Female sex steroid hormones: from receptors to networks to performance—actions on the sensorimotor system , 1994, Progress in Neurobiology.

[12]  J. A. Peters,et al.  Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[13]  R. Harris,et al.  General anesthetics potentiate gamma-aminobutyric acid actions on gamma-aminobutyric acidA receptors expressed by Xenopus oocytes: lack of involvement of intracellular calcium. , 1992, The Journal of pharmacology and experimental therapeutics.

[14]  E. Costa,et al.  Molecular mechanisms of the partial allosteric modulatory effects of bretazenil at gamma-aminobutyric acid type A receptor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[15]  M. Majewska,et al.  Neurosteroids: Endogenous bimodal modulators of the GABAA receptor mechanism of action and physiological significance , 1992, Progress in Neurobiology.

[16]  I. Martin,et al.  Multiple benzodiazepine receptors: no reason for anxiety. , 1992, Trends in pharmacological sciences.

[17]  M. Simmonds Modulation of the GABAA receptor by steroids , 1991 .

[18]  W. Haefely,et al.  Novel anxiolytics that act as partial agonists at benzodiazepine receptors. , 1990, Trends in pharmacological sciences.

[19]  K. Gee,et al.  Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex , 1990, Neuroscience & Biobehavioral Reviews.

[20]  K. Gee,et al.  5α-pregnan-3α,20α-diol behaves like a partial agonist in the modulation of GABA-stimulated chlride ion uptake by synaptoneurosomes , 1989 .

[21]  B. McEwen,et al.  Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action. , 1988, The Journal of pharmacology and experimental therapeutics.

[22]  R. Miledi,et al.  Actions of pentobarbital on rat brain receptors expressed in Xenopus oocytes , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.