论文信息 - A silicon pixel detector system as an imaging tool for proton beam characterization

A silicon pixel detector system as an imaging tool for proton beam characterization

High energy protons represent a very promising alternative in the tumor irradiation, as respect the photon and electron beams. In Italy, the first and at present the only proton-therapy facility, CATANA (Centro di AdroTerapia e Applicazioni Nucleari Avanzate), was built in Catania, at the Istituto Nazionale di Fisica Nucleare-Laboratori Nazionali del Sud (INFN-LNS). Here a 62 MeV proton beam, produced by a Superconducting Cyclotron (SC), is used for the treatment of shallow tumors like those of the ocular region. A beam monitoring system, based on ion chambers for dose monitoring and on silicon diodes scanning the beam cross section for the beam quality control. Moreover, gaf-chromic films are used to measure the geometric features of the beams. Even though these systems are stable and reliable, nevertheless they are time consuming and, in the gas-chromic film case, they require an off-line analysis. In this paper we present a feasibility study for using a silicon pixel detector as device for proton beams imaging and characterization. We present the performance of such a device exposed to the CATANA proton beam in terms of dose, dose rate and exposure time response.

[1] M. G. Bisogni,et al. Medipix2 as a tool for proton beam characterization , 2009 .

[2] V. Sipala,et al. YAP(Ce) crystal characterization with proton beam up to 60 MeV , 2008 .

[3] M. G. Sabini,et al. Proton therapy detector studies under the experience gained at the CATANA facility , 2007 .

[4] S. Incerti,et al. Geant4 developments and applications , 2006, IEEE Transactions on Nuclear Science.

[5] M. G. Sabini,et al. A 62 MeV proton beam for the treatment of ocular melanoma at Laboratori Nazionali del Sud-INFN (CATANIA) , 2003, 2003 IEEE Nuclear Science Symposium. Conference Record (IEEE Cat. No.03CH37515).

[6] M. G. Sabini,et al. Clinical Application of Proton Beams in the Treatment of Uveal Melanoma: The First Therapies Carried Out in Italy and Preliminary Results (Catana Project) , 2003, Tumori.

[7] M. G. Sabini,et al. 62 AMEV PROTON BEAM FOR THE TREATMENT OF OCULAR MELANOMA AT LABORATORI NAZIONALI DEL SUD – INFN (CATANIA) , 2003 .

[8] R. Dinapoli,et al. Medipix2, a 64k pixel read out chip with 55 /spl mu/m square elements working in single photon counting mode , 2001, 2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310).