Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis

[1]  A. McMahon,et al.  A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney , 2009, Development.

[2]  G. Pazour,et al.  Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease , 2008, The Journal of cell biology.

[3]  Manfred Gessler,et al.  Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease , 2008, Nature Genetics.

[4]  P. Igarashi,et al.  Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. , 2008, Human molecular genetics.

[5]  M. Buechner,et al.  CRIP homologues maintain apical cytoskeleton to regulate tubule size in C. elegans. , 2008, Developmental biology.

[6]  V. Tsarouhas,et al.  COPI Vesicle Transport Is a Common Requirement for Tube Expansion in Drosophila , 2008, PloS one.

[7]  A. McMahon,et al.  Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state. , 2008, Developmental biology.

[8]  S. Hayashi,et al.  A wave of EGFR signaling determines cell alignment and intercalation in the Drosophila tracheal placode , 2007, Development.

[9]  S. Fisher,et al.  Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response , 2007, Nature Genetics.

[10]  H. A. Hartman,et al.  Cessation of renal morphogenesis in mice. , 2007, Developmental biology.

[11]  A. Schedl Renal abnormalities and their developmental origin , 2007, Nature Reviews Genetics.

[12]  J. Vincent,et al.  Oriented cell divisions in the extending germband of Drosophila , 2007, Development.

[13]  V. Tsarouhas,et al.  Sequential pulses of apical epithelial secretion and endocytosis drive airway maturation in Drosophila. , 2007, Developmental cell.

[14]  A. McMahon,et al.  Wnt/β-catenin signaling regulates nephron induction during mouse kidney development , 2007, Development.

[15]  Courtney M. Karner,et al.  Molecular regulation of kidney development: is the answer blowing in the Wnt? , 2007, Pediatric Nephrology.

[16]  T. Benzing,et al.  Wnt signaling in polycystic kidney disease. , 2007, Journal of the American Society of Nephrology : JASN.

[17]  O. Ibraghimov-Beskrovnaya Targeting Dysregulated Cell Cycle and Apoptosis for Polycystic Kidney Disease Therapy , 2007, Cell cycle.

[18]  M. Hartnett,et al.  Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation. , 2007, Blood.

[19]  M. Palladino,et al.  A pump-independent function of the Na,K-ATPase is required for epithelial junction function and tracheal tube-size control , 2007, Development.

[20]  R. O. Stuart,et al.  Rho kinase acts at separate steps in ureteric bud and metanephric mesenchyme morphogenesis during kidney development. , 2006, Differentiation; research in biological diversity.

[21]  U. Certa,et al.  Polychaetoid/ZO-1 Is Required for Cell Specification and Rearrangement during Drosophila Tracheal Morphogenesis , 2006, Current Biology.

[22]  Courtney M. Karner,et al.  Planar cell polarity and vertebrate organogenesis. , 2006, Seminars in cell & developmental biology.

[23]  B. Goldstein,et al.  Wnt signals can function as positional cues in establishing cell polarity. , 2006, Developmental cell.

[24]  M. Krasnow,et al.  serpentine and vermiform Encode Matrix Proteins with Chitin Binding and Deacetylation Domains that Limit Tracheal Tube Length in Drosophila , 2006, Current Biology.

[25]  V. Tsarouhas,et al.  Septate-Junction-Dependent Luminal Deposition of Chitin Deacetylases Restricts Tube Elongation in the Drosophila Trachea , 2006, Current Biology.

[26]  G. Tear,et al.  mummy/cystic encodes an enzyme required for chitin and glycan synthesis, involved in trachea, embryonic cuticle and CNS development--analysis of its role in Drosophila tracheal morphogenesis. , 2005, Developmental biology.

[27]  J. Davies,et al.  A role for microfilament-based contraction in branching morphogenesis of the ureteric bud. , 2005, Kidney international.

[28]  Xi Lin,et al.  Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway , 2005, Nature Genetics.

[29]  A. McMahon,et al.  Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. , 2005, Developmental cell.

[30]  Ray Keller,et al.  Planar Cell Polarity Genes Regulate Polarized Extracellular Matrix Deposition during Frog Gastrulation , 2005, Current Biology.

[31]  O. A. Cabello,et al.  Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways , 2005, Nature Genetics.

[32]  P. Gros,et al.  Independent Mutations in Mouse Vangl2 That Cause Neural Tube Defects in Looptail Mice Impair Interaction with Members of the Dishevelled Family* , 2004, Journal of Biological Chemistry.

[33]  G. Beitel,et al.  A junctional problem of apical proportions: epithelial tube-size control by septate junctions in the Drosophila tracheal system. , 2004, Current opinion in cell biology.

[34]  M. L. Watkins,et al.  Polyductin, the PKHD1 gene product, comprises isoforms expressed in plasma membrane, primary cilium, and cytoplasm. , 2004, Kidney international.

[35]  Mark S. Miller,et al.  A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney , 2004, Development.

[36]  Scott E. Fraser,et al.  Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation , 2004, Nature.

[37]  N. LaRusso,et al.  Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia. , 2003, Human molecular genetics.

[38]  S. Baker,et al.  IFT20 Links Kinesin II with a Mammalian Intraflagellar Transport Complex That Is Conserved in Motile Flagella and Sensory Cilia* , 2003, Journal of Biological Chemistry.

[39]  T. Strachan,et al.  Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination , 2003, Nature Genetics.

[40]  Y. Saijoh,et al.  The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia , 2003, Development.

[41]  L. Goldstein,et al.  Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[42]  Jing Zhou,et al.  Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells , 2003, Nature Genetics.

[43]  Xi He,et al.  Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. , 2003, Genes & development.

[44]  C. Samakovlis,et al.  Grainy head controls apical membrane growth and tube elongation in response to Branchless/FGF signalling , 2003, Development.

[45]  M. Krasnow,et al.  Tube Morphogenesis Making and Shaping Biological Tubes , 2003, Cell.

[46]  L. Guay-Woodford,et al.  The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. , 2002, Journal of the American Society of Nephrology : JASN.

[47]  P. Igarashi,et al.  Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract. , 2002, Journal of the American Society of Nephrology : JASN.

[48]  R. Keller,et al.  The planar cell polarity gene strabismus regulates convergence and extension and neural fold closure in Xenopus. , 2002, Developmental biology.

[49]  Kathleen R. Cho,et al.  Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling. , 2002, The Journal of biological chemistry.

[50]  G. Pazour,et al.  Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease , 2002, Current Biology.

[51]  F. Marlow,et al.  Zebrafish Rho Kinase 2 Acts Downstream of Wnt11 to Mediate Cell Polarity and Effective Convergence and Extension Movements , 2002, Current Biology.

[52]  Andrew P McMahon,et al.  Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. , 2002, Developmental biology.

[53]  C. Bugg,et al.  Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium. , 2002, American journal of physiology. Renal physiology.

[54]  P. D’Eustachio,et al.  Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease. , 2002, The Journal of clinical investigation.

[55]  Hans Clevers,et al.  Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors , 2002, Molecular and Cellular Biology.

[56]  Choun-Ki Joo,et al.  Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway , 2002, Molecular and Cellular Biology.

[57]  A. Kahn,et al.  Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the β-catenin gene , 2001, Oncogene.

[58]  J. Wallingford,et al.  Regulation of convergent extension in Xenopus by Wnt5a and Frizzled-8 is independent of the canonical Wnt pathway. , 2001, The International journal of developmental biology.

[59]  Andrew Tomlinson,et al.  arrow encodes an LDL-receptor-related protein essential for Wingless signalling , 2000, Nature.

[60]  J. Riou,et al.  Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. , 2000, Development.

[61]  J. Smith,et al.  Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. , 2000, Development.

[62]  Robert Geisler,et al.  Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation , 2000, Nature.

[63]  Scott E. Fraser,et al.  Dishevelled controls cell polarity during Xenopus gastrulation , 2000, Nature.

[64]  M. Taketo,et al.  Intestinal polyposis in mice with a dominant stable mutation of the β‐catenin gene , 1999, The EMBO journal.

[65]  R. B. Thomson,et al.  Immunolocalization of Ksp-cadherin in the adult and developing rabbit kidney. , 1999, American journal of physiology. Renal physiology.

[66]  M. Boutros,et al.  Dishevelled Activates JNK and Discriminates between JNK Pathways in Planar Polarity and wingless Signaling , 1998, Cell.

[67]  M. Concha,et al.  Oriented cell divisions and cellular morphogenesis in the zebrafish gastrula and neurula: a time-lapse analysis. , 1998, Development.

[68]  Weining Lu,et al.  Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation , 1997, Nature Genetics.

[69]  D. Strutt,et al.  The role of RhoA in tissue polarity and Frizzled signalling , 1997, Nature.

[70]  J. Shih,et al.  Cell motility driving mediolateral intercalation in explants of Xenopus laevis. , 1992, Development.

[71]  P. Adler,et al.  A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains , 1989, Nature.

[72]  Amy E. Shyer,et al.  Kif3a constrains β-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms , 2008, Nature Cell Biology.

[73]  Jean-François Nicolas,et al.  Defective planar cell polarity in polycystic kidney disease , 2006, Nature Genetics.

[74]  N. Perrimon,et al.  The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. , 1994, Genes & development.