Solid supports for combinatorial chemistry.

Over the past year, numerous techniques have been used to study the resins commonly utilised in solid-phase synthesis to allow a greater understanding of the chemical nature and the physical properties of the supports. In addition, to overcome some of the drawbacks of existing materials, several new resins and new methods of handling solid supports have been developed. New methodologies have also been introduced to simplify the preparation of solid supports.

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[2]  M. Grøtli,et al.  HYDRA: A novel hydroxy and amine functionalised resin synthesised by reductive amination of PEG aldehyde and a polyamine , 2000 .

[3]  J. Fréchet,et al.  Hydrophilic polymer supports for solid-phase synthesis: preparation of poly(ethylene glycol) methacrylate polymer beads using "classical" suspension polymerization in aqueous medium and their application in the solid-phase synthesis of hydantoins. , 2001, Journal of combinatorial chemistry.

[4]  H. Fenniri,et al.  Barcoded resins: a new concept for polymer-supported combinatorial library self-deconvolution. , 2001, Journal of the American Chemical Society.

[5]  Mark Bradley,et al.  Tagging in combinatorial chemistry: the use of coloured and fluorescent beads , 1997 .

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[7]  B. Yan,et al.  Repeated use of solid supports in combinatorial synthesis: the case of Marshall resin recycling. , 2001, Journal of combinatorial chemistry.

[8]  D. Sherrington,et al.  Reversibly collapsible macroporous poly(styrene-divinylbenzene) resins , 2000 .

[9]  J. Fréchet,et al.  Solid-phase acylating reagents in new format: macroporous polymer disks. , 2001, Journal of combinatorial chemistry.

[10]  W. Brocklesby,et al.  Site distribution in resin beads as determined by confocal Raman spectroscopy. , 2001, Chemistry.

[11]  R. Brock,et al.  Spatially resolved single bead analysis: homogeneity, diffusion, and adsorption in cross-linked polystyrene. , 2001, Chemistry.

[12]  Jean M. J. Fréchet,et al.  Preparation of Porous Poly(styrene-co-divinylbenzene) Monoliths with Controlled Pore Size Distributions Initiated by Stable Free Radicals and Their Pore Surface Functionalization by Grafting , 2001 .

[13]  Towards the DRED of Resin‐Supported Combinatorial Libraries: A Non‐Invasive Methodology Based on Bead Self‐Encoding and Multispectral Imaging , 2000 .

[14]  J. A. Malikayil,et al.  Polytetrahydrofuran cross-linked polystyrene resins for solid-phase organic synthesis. , 2001, Journal of combinatorial chemistry.

[15]  George Barany,et al.  CLEAR : A NOVEL FAMILY OF HIGHLY CROSS-LINKED POLYMERIC SUPPORTS FOR SOLID-PHASE PEPTIDE SYNTHESIS , 1996 .

[16]  M. Bradley,et al.  Influence of resin cross-linking on solid-phase chemistry. , 2001, Journal of combinatorial chemistry.

[17]  K. S. Kumar,et al.  Syntheses, characterization and application of cross-linked polystyrene-ethyleneglycol acrylate resin (CLPSER) as a novel polymer support for polypeptide syntheses. , 2001, The journal of peptide research : official journal of the American Peptide Society.

[18]  Thin film format for polymer supports: synthesis and chemical modification , 2000 .

[19]  M. Bradley,et al.  Solid phase synthesis of aryl-ether dendrimers , 2001 .

[20]  Yoon-Sik Lee,et al.  Preparation of tris-based dendrimer-grafted core-shell type resin for solid-phase peptide synthesis , 2001 .

[21]  J. Fréchet,et al.  Grafted macroporous polymer monolithic disks: a new format of scavengers for solution-phase combinatorial chemistry. , 2001, Journal of combinatorial chemistry.