Subvalvular calcification of mitral valve.

The pathological processes that develop in the heart with ageing are numerous. One of these processes is mitral ring calcification (Fertman and Wolff, 1946; Geill, 1951). It occurs frequently and has been variously ascribed to rheumatic disease, rheumatoid disease, and endocarditis of various aetiologies; it is more generally regarded as an endstage degenerative disorder similar to the Monckeberg type of aortic valve calcification. In a study of adult hearts we have found that calcification in the region of the mitral ring occurs more frequently than is generally recognized, and that in many hearts the site of calcification is mainly in the subvalve angle or recess of the mitral valve and not in the true valve ring. Our studies have shown that this type of calcification occurs in organizing thrombi which can be demonstrated in the subvalve recess.

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