The importance of physical activity in the rehabilitation program of female oncopediatric patients

Background. In the last 20 years, the survival rate in pediatric cancer patients has increased considerably, raising awareness about fertility and life quality. It is well known that physical activity plays an important role in cancer prevention and rehabilitation. Aims. The current study aimed to raise awareness about oncofertility and poor fertility counselling, highlighting the need for improvement and whether or not physical activity should be introduced as a rehabilitation method in cancer patients. Methods. Of 125 female patients, only 30 were included in the study after applying the inclusion criteria. The subjects received a questionnaire containing 14 questions about their fertility status, oncologic treatment, and rehabilitation counselling. Results. The results showed that more than 86% of the subjects did not receive rehabilitation counselling, including fertility preservation methods and physical activity, and 80% could not conceive after cancer treatment. The results were statistically insignificant (p>0.05) because of the small number of subjects included in the study. Conclusions. The lack of rehabilitation counselling leads to an increase in infertility and a decrease in life quality. Rehabilitation through physical activity should become a standard care option for these patients, improving mental and physical health.

[1]  Maiken Hjerming,et al.  How Do Young Women with Cancer Experience Oncofertility Counselling during Cancer Treatment? A Qualitative, Single Centre Study at a Danish Tertiary Hospital , 2021, Cancers.

[2]  S. Wittekind,et al.  Exercise testing and cardiac rehabilitation in patients treated for cancer , 2020, Journal of Thrombosis and Thrombolysis.

[3]  A. Paradiso,et al.  Breast cancer: an update on treatment-related infertility , 2020, Journal of Cancer Research and Clinical Oncology.

[4]  A. Haig,et al.  ASPECTS OF CANCER REHABILITATION: AN AUSTRIAN PERSPECTIVE Cancer rehabilitation as an essential component of quality care and survivorship from an international perspective , 2022 .

[5]  R. Atun,et al.  Global childhood cancer survival estimates and priority-setting: a simulation-based analysis. , 2019, The Lancet. Oncology.

[6]  M. H. van den Berg,et al.  Uterine function, pregnancy complications, and pregnancy outcomes among female childhood cancer survivors. , 2019, Fertility and sterility.

[7]  R. Marci,et al.  Lifestyle and fertility: the influence of stress and quality of life on female fertility , 2018, Reproductive Biology and Endocrinology.

[8]  R. Marci,et al.  Radiations and female fertility , 2018, Reproductive Biology and Endocrinology.

[9]  M. Kristoffersen,et al.  Combined aerobic and resistance training improves physical capacity in women treated for gynecological cancer , 2018, Supportive Care in Cancer.

[10]  K. Winters-Stone,et al.  A Systematic Review of Exercise Systematic Reviews in the Cancer Literature (2005‐2017) , 2017, PM & R : the journal of injury, function, and rehabilitation.

[11]  J. Silver,et al.  The Case for Prehabilitation Prior to Breast Cancer Treatment , 2017, PM & R : the journal of injury, function, and rehabilitation.

[12]  H. Kitchen,et al.  A review of patient-reported outcome measures to assess female infertility-related quality of life , 2017, Health and Quality of Life Outcomes.

[13]  A. Lorenzo,et al.  Fertility preservation options for children and adolescents with cancer. , 2017, Canadian Urological Association journal = Journal de l'Association des urologues du Canada.

[14]  A. Purushotham,et al.  CanWalk: a feasibility study with embedded randomised controlled trial pilot of a walking intervention for people with recurrent or metastatic cancer , 2017, BMJ Open.

[15]  L. Denehy,et al.  Exercise interventions for patients with gynaecological cancer: a systematic review and meta-analysis. , 2016, Physiotherapy.

[16]  M. Hudson,et al.  Fertility preservation in children , adolescents , and young adults with cancer , 2016 .

[17]  Kayla L. Stratton,et al.  Pregnancy after chemotherapy in male and female survivors of childhood cancer treated between 1970 and 1999: a report from the Childhood Cancer Survivor Study cohort. , 2016, The Lancet. Oncology.

[18]  Alberto Revelli,et al.  Cancer and fertility preservation: international recommendations from an expert meeting , 2016, BMC Medicine.

[19]  M. Sağlam,et al.  Do Yoga and Aerobic Exercise Training Have Impact on Functional Capacity, Fatigue, Peripheral Muscle Strength, and Quality of Life in Breast Cancer Survivors? , 2015, Integrative cancer therapies.

[20]  C. Holman,et al.  Adverse Obstetric and Perinatal Outcomes following Treatment of Adolescent and Young Adult Cancer: A Population-Based Cohort Study , 2014, PloS one.

[21]  M. Keats,et al.  The physical activity preferences of gynecologic cancer survivors. , 2014, Oncology nursing forum.

[22]  G. Armstrong,et al.  Male infertility in long-term survivors of pediatric cancer: a report from the childhood cancer survivor study , 2014, Journal of Cancer Survivorship.

[23]  N. Pavlidis,et al.  Cancer, pregnancy and fertility: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. , 2013, Annals of oncology : official journal of the European Society for Medical Oncology.

[24]  K. Oktay,et al.  Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[25]  L. Beatty,et al.  The psychosocial impact of cancer-related infertility on women: a review and comparison. , 2013, Clinical journal of oncology nursing.

[26]  S. Ogle,et al.  Fertility preservation for patients with cancer , 2022, Journal of the Korean Medical Association.

[27]  C. Kelnar,et al.  Late reproductive sequelae following treatment of childhood cancer and options for fertility preservation. , 2002, Best practice & research. Clinical endocrinology & metabolism.

[28]  D. Meirow,et al.  Subclinical depletion of primordial follicular reserve in mice treated with cyclophosphamide: clinical importance and proposed accurate investigative tool. , 1999, Human reproduction.

[29]  S. Shalet,et al.  Gonadal damage from chemotherapy and radiotherapy. , 1998, Endocrinology and metabolism clinics of North America.

[30]  S. Sernia,et al.  Oncofertility: the importance of counseling for fertility preservation in cancer patients , 2021 .

[31]  Maike G. Sweegers,et al.  Edinburgh Research Explorer Effects and moderators of exercise on quality of life and physical function in patients with cancer , 2016 .

[32]  M. Riddell,et al.  Advances in Exercise, Physical Activity, and Diabetes Mellitus. , 2016, Diabetes technology & therapeutics.

[33]  C. Carlson,et al.  Cancer rehabilitation. , 1988, Oncology nursing forum.