Aichberger, K.J., Mayerhofer, M., Krauth, M.T., Vales, A., Kondo, R., Derdak, S., Pickl, W.F., Selzer, E., Deininger, M., Druker, B.J., Sillaber, C., Esterbauer, H. & Valent, P. (2005) Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds. Cancer Research, 65, 9436–9444. Aichberger, K.J., Jagani, Z., Song, K., Kutok, M.R., Melet, A., Santos, T., Grassian, A., Ghaffari, S., Wu, C., Ren, R., Yeckes Rodin, H., Miller, K. & Khosravi-Far, R. (2009) Proteasome inhibition causes regression of leukemia and abrogates BCR-ABL-induced evasion of apoptosis in part through regulation of forkhead tumor suppressors. Cancer Research, 69, 6546–6555. Boultwood, J. & Wainscoat, J.S. (2007) Gene silencing by DNA methylation in haematological malignancies. British Journal of Haematology, 138, 3–11. Jelinek, J., Gharibyan, V., Estecio, M.R.H., Kondo, K., He, R., Chung, W., Lu, Y., Zhang, N., Liang, S., Kantarjian, H.M., Cortes, J.E. & Issa, J.P.J. (2011) Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortnened survival in chronic myelogenous leukemia. PLoS ONE, 6, e22110. Kuribara, R., Honda, H., Matsui, H., Shinjyo, T., Inukai, T., Sugita, K., Nakazawa, S., Hirai, H., Ozawa, K. & Inaba, T. (2004) Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors. Molecular and Cellular Biology, 24, 6172–6183. Kuroda, J., Puthalakath, H., Cragg, M.S., Kelly, P. N., Bouillet, P., Huang, D.C.S., Kimura, S., Ottmann, O.G., Druker, B.J., Villunger, A., Roberts, A.W. & Strasser, A. (2006) Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic. Proceedings National Academy Science USA, 103, 14907–14912. Mancini, M., Veljkovic, N., Leo, E., Aluigi, M., Borsi, E., Galloni, C., Iacobucci, I., Barbieri, E. & Santucci, M.A. (2012) Cytoplasmatic compartimentalization by Bcr-Abl promotes TET2 lossof-function in chronic myeloid leukemia. Journal of Cellular Biochemistry, 113, 2765–2774. Ng, K.P., Hillmer, A.M., Chuah, C.T., Juan, W.C., Ko, T.K., Teo, A.S., Ariyaratne, P.N., Takahashi, N., Sawada, K., Fei, Y., Soh, S., Lee, W.H., Huang, J.W., Allen, Jr, J.C., Woo, X.Y., Nagarajan, N., Kumar, V., Thalamuthu, A., Poh, W.T., Ang, A.L., Mya, H.T., How, G.F., Yang, L.Y., Koh, L.P., Chowbay, B., Chang, C.T., Nadarajan, V.S., Chng, W.J., Than, H., Lim, L.C., Goh, Y.T., Zhang, S., Poh, D., Tan, P., Seet, J.E., Ang, M.K., Chau, N. M., Ng, Q.S., Tan, D.S., Soda, M., Isobe, K., Nöthen, M.M., Wong, T.Y., Shahab, A., Ruan, X., Cacheux-Rataboul, V., Sung, W.K., Tan, E.H., Yatabe, Y., Mano, H., Soo, R.A., Chin, T.M., Lim, W.T., Ruan, Y. & Ong, S.T. (2012) A common BIM deletion polymorphism mediates intrinsic resistance and inferior response to tyrosine kinase inhibitors in cancer. Nature Medicine, 18, 521– 528. San José-Eneriz, E., Agirre, X., Jiménez-Velasco, A., Cordeu, L., Martin, V., Arqueros, V., Garate, L., Fresquet, V., Cervantes, F., Martinez-Climent, J.A., Heiniger, A., Torres, A., Prosper, F. & Roman-Gomez, J. (2009) Epigenetic downregulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukemia. European Journal of Cancer, 45, 1877–1889. Youle, R.J. & Strasser, S. (2008) The BCL-2 protein family: opposing activities that mediate cell death. Nature Reviews. Molecular Cell Biology, 9, 47–59.
[1]
M. Nöthen,et al.
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
,
2012,
Nature Medicine.
[2]
S. Vesely,et al.
Antithrombotic therapy in neonates and children: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
,
2012,
Chest.
[3]
L. Sandvik,et al.
Long-term outcome after additional catheter-directed thrombolysis versus standard treatment for acute iliofemoral deep vein thrombosis (the CaVenT study): a randomised controlled trial
,
2012,
The Lancet.
[4]
P. Monagle,et al.
Definition of clinical efficacy and safety outcomes for clinical trials in deep venous thrombosis and pulmonary embolism in children
,
2011,
Journal of thrombosis and haemostasis : JTH.
[5]
M. Manco‐Johnson,et al.
Percutaneous mechanical and pharmacomechanical thrombolysis for occlusive deep vein thrombosis of the proximal limb in adolescent subjects: findings from an institution-based prospective inception cohort study of pediatric venous thromboembolism.
,
2011,
Journal of vascular and interventional radiology : JVIR.
[6]
L. Raffini,et al.
Varied opinions on thrombolysis for venous thromboembolism in infants and children: Findings from a survey of pediatric hematology–oncology specialists
,
2009,
Pediatric blood & cancer.
[7]
M. Streiff,et al.
Catheter-Directed Thrombolysis of Inferior Vena Cava Thrombosis in a 13-Day-Old Neonate and Review of Literature
,
2008,
Cardiovascular and Interventional Radiology.
[8]
M. Manco‐Johnson,et al.
A thrombolytic regimen for high-risk deep venous thrombosis may substantially reduce the risk of postthrombotic syndrome in children.
,
2007,
Blood.
[9]
L. Valentino,et al.
Low-Dose Tissue Plasminogen Activator Thrombolysis in Children
,
2003,
Journal of pediatric hematology/oncology.
[10]
G. Seabrook,et al.
Catheter-directed thrombolysis for lower extremity deep venous thrombosis: report of a national multicenter registry.
,
1999,
Radiology.
[11]
G. Pantely,et al.
Long-Term Outcome
,
2005
.