Immobilized L-asparaginase-L-glutaminase from Acinetobacter glutaminasificans in microspheres: some properties in vivo and in an extracorporeal system

[1]  A. Lavin,et al.  Enzymatic removal of bilirubin from blood: a potential treatment for neonatal jaundice. , 1985, Science.

[2]  L. Callegaro,et al.  Applications of bioreactors in medicine. , 1983, The International journal of artificial organs.

[3]  I. Sjöholm,et al.  Use of immobilized L-asparaginase in acrylic microparticles in an extracorporeal hollow-fiber dialyzer. , 1983, The Journal of pharmacology and experimental therapeutics.

[4]  G. Vecchio,et al.  L-Glutaminase and L-Asparaginase by Extracorporeal Route in Acute Lymphoblastic Leukemia Therapy , 1981, The International journal of artificial organs.

[5]  R. Warrell,et al.  Phase I evaluation of succinylated Acinetobacter glutaminase-asparaginase in adults. , 1980, Cancer research.

[6]  I. Sjöholm,et al.  Acrylic microspheres in vivo. II. The effect in rat of L-asparaginase given in microparticles of polyacrylamide. , 1979, The Journal of pharmacology and experimental therapeutics.

[7]  H. Sather,et al.  Effective dose of L-asparaginase for induction of remission in previously treated children with acute lymphocytic leukemia: a report from Childrens Cancer Study Group. , 1979, Cancer research.

[8]  H. Halvorson,et al.  A new extracorporeal reactor-dialyzer for enzyme therapy using immobilized L-asparaginase. , 1979, The Journal of pharmacology and experimental therapeutics.

[9]  I. Sjöholm,et al.  Improved stability of proteins immobilized in microparticles prepared by a modified emulsion polymerization technique. , 1978, Journal of pharmaceutical sciences.

[10]  G. Gregoriadis,et al.  Tumour regression with liposome-entrapped asparaginase: some immunological advantages. , 1976, Biochemical Society transactions.

[11]  J. Palmblad,et al.  Hypersensitive reactions and antibody formation during L‐asparaginase treatment of children and adults with acute leukemia , 1976, Cancer.

[12]  W. Dolowy,et al.  Isolation, crystallization, and properties of Achromobacteraceae glutaminase-asparaginase with antitumor activity. , 1972, The Journal of biological chemistry.

[13]  R. Handschumacher,et al.  Evaluation of L-asparagine metabolism in animals and man. , 1970, Cancer research.

[14]  C. Haskell,et al.  l-asparaginase resistance in human leukemia--asparagine synthetase. , 1969, Biochemical pharmacology.

[15]  S. Hjertén.  "Molecular sieve" chromatography on polyacrylamide gels, prepared according to a simplified method. , 1962, Archives of biochemistry and biophysics.

[16]  J. Uren.  Pharmacology of L-asparaginase and the effects of host and enzyme modification. , 1981, Cancer treatment reports.

[17]  Broome Jd.  L-Asparaginase: discovery and development as a tumor-inhibitory agent. , 1981 .

[18]  T. Chang.  L-Asparaginase Immobilized within Semipermeable Microcapsules: in vitro and in vivo Stability , 1972 .