Parallel RNA-strand recognition by 2'-amino-beta-L-LNA.

[1]  J. Wengel,et al.  Functionalized 2'-amino-alpha-L-LNA: directed positioning of intercalators for DNA targeting. , 2009, The Journal of organic chemistry.

[2]  N. Badgujar,et al.  Fine tuning of electrostatics around the internucleotidic phosphate through incorporation of modified 2',4'-carbocyclic-LNAs and -ENAs leads to significant modulation of antisense properties. , 2009, The Journal of organic chemistry.

[3]  J. Wengel,et al.  Nucleic acid structural engineering using pyrene-functionalized 2'-amino-alpha-L-LNA monomers and abasic sites. , 2008, The Journal of organic chemistry.

[4]  K. Miyashita,et al.  Design, synthesis, and properties of 2',4'-BNA(NC): a bridged nucleic acid analogue. , 2008, Journal of the American Chemical Society.

[5]  S. Maiti,et al.  Perspectives on chemistry and therapeutic applications of Locked Nucleic Acid (LNA). , 2007, Chemical reviews.

[6]  J. Wengel,et al.  2′‐N‐(Pyren‐1‐yl)acetyl‐2′‐Amino‐α‐L‐LNA: Synthesis and Detection of Single Nucleotide Mismatches in DNA and RNA Targets , 2007, Chembiochem : a European journal of chemical biology.

[7]  J. Wengel,et al.  Effective modulation of DNA duplex stability by reversible transition metal complex formation in the minor groove. , 2007, Journal of the American Chemical Society.

[8]  M. Damha,et al.  Oxepane nucleic acids: synthesis, characterization, and properties of oligonucleotides bearing a seven-membered carbohydrate ring. , 2007, Journal of the American Chemical Society.

[9]  Gaëlle Deglane,et al.  5-Propynylamino α-deoxyuridine promotes DNA duplex stabilization of anionic and neutral but not cationic α-oligonucleotides , 2007 .

[10]  C. Leumann,et al.  Synthesis and Pairing Properties of α‐Tricyclo‐DNA , 2006 .

[11]  P. Nielsen,et al.  Analogues of a locked nucleic acid with three-carbon 2',4'-linkages: synthesis by ring-closing metathesis and influence on nucleic acid duplex stability and structure. , 2006, The Journal of organic chemistry.

[12]  J. Wengel,et al.  Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and Tetracyclic “Locked LNA”† , 2006 .

[13]  E. Vivés,et al.  Impact of the Guanidinium Group on Hybridization and Cellular Uptake of Cationic Oligonucleotides , 2006, Chembiochem : a European journal of chemical biology.

[14]  J. Wengel,et al.  Multilabeled pyrene-functionalized 2'-amino-LNA probes for nucleic acid detection in homogeneous fluorescence assays. , 2005, Journal of the American Chemical Society.

[15]  J. Wengel,et al.  Targeting of mixed sequence double-stranded DNA using pyrene-functionalized 2′-amino-α-L-LNA , 2005 .

[16]  P. Nielsen,et al.  An alpha-D-configured bicyclic nucleoside restricted in an E-type conformation: synthesis and parallel RNA recognition. , 2005, The Journal of organic chemistry.

[17]  J. Wengel,et al.  Parallel nucleic acid recognition by the LNA (locked nucleic acid) stereoisomers β-L-LNA and α-D-LNA; studies in the mirror image world , 2004 .

[18]  B. Lebleu,et al.  Cationic phosphoramidate alpha-oligonucleotides efficiently target single-stranded DNA and RNA and inhibit hepatitis C virus IRES-mediated translation. , 2003, Nucleic acids research.

[19]  D. Kohda,et al.  Thermodynamic study of hybridization properties of heterochiral nucleic acids. , 2003, Biochemical and biophysical research communications.

[20]  J. Wengel,et al.  Functionalized LNA (locked nucleic acid): high-affinity hybridization of oligonucleotides containing N-acylated and N-alkylated 2'-amino-LNA monomers. , 2003, Chemical communications.

[21]  Jens Kurreck,et al.  Antisense technologies. Improvement through novel chemical modifications. , 2003, European journal of biochemistry.

[22]  J. Wengel,et al.  Synthesis of 2'-amino-LNA: a new strategy. , 2003, Organic & biomolecular chemistry.

[23]  P. Nielsen,et al.  α‐LNA (Locked Nucleic Acid with α‐D‐Configuration): Synthesis and Selective Parallel Recognition of RNA , 2002 .

[24]  C. Leumann,et al.  Synthesis and Incorporation into α-DNA of a Novel Conformationally Constrained α-Nucleoside Analogue , 2002 .

[25]  S. Pitsch,et al.  The eight stereoisomers of LNA (Locked Nucleic Acid): A remarkable family of strong RNA binding molecules , 2000 .

[26]  P. Nielsen,et al.  α-LNA, locked nucleic acid with α-D-configuration , 2000 .

[27]  B. Rayner,et al.  Chiral and steric effects in the efficient binding of alpha-anomeric deoxyoligonucleoside N-alkylphosphoramidates to ssDNA and RNA. , 1999, Nucleic acids research.

[28]  J. Wengel,et al.  Synthesis of 2‘-Amino-LNA: A Novel Conformationally Restricted High-Affinity Oligonucleotide Analogue with a Handle , 1998 .

[29]  Y. Hari,et al.  Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2'-O,4'- C-methyleneribonucleosides , 1998 .

[30]  K. Pongracz,et al.  alpha-Oligodeoxyribonucleotide N3'-->P5' phosphoramidates: synthesis and duplex formation. , 1998, Nucleic acids research.

[31]  B. Rayner,et al.  α-Oligodeoxynucleotides containing 5-propynyl analogs of α-deoxyuridine and α-deoxycytidine: Synthesis and base pairing properties , 1998 .

[32]  Poul Nielsen,et al.  LNA (locked nucleic acids): synthesis and high-affinity nucleic acid recognition , 1998 .

[33]  P. A. Giannaris,et al.  Antisense L/D-oligodeoxynucleotide chimeras: nuclease stability, base-pairing properties, and activity at directing ribonuclease H. , 1994, Biochemistry.

[34]  M. Chassignol,et al.  Oligo-α-deoxyribonucleotides with a modified nucleic base and covalently linked to reactive agents , 1993 .

[35]  B. Sproat,et al.  Comparative evaluation of seven oligonucleotide analogues as potential antisense agents. , 1993, Journal of medicinal chemistry.

[36]  F. Vovelle,et al.  Solution structure of the parallel-stranded duplex oligonucleotide alpha-d(TCTAAAC)-beta-d(AGATTTG) via complete relaxation matrix analysis of the NOE effects and molecular mechanics calculations. , 1989, Biochemistry.

[37]  B. Rayner,et al.  α-DNA IX: parallel annealing of α-anomeric oligodeoxyribonucleotides to natural mRNA is required for interference in RNase H mediated hydrolysis and reverse transcription , 1989 .

[38]  E. Wickstrom,et al.  alpha-Oligodeoxynucleotide stability in serum, subcellular extracts and culture media. , 1986, Journal of biochemical and biophysical methods.

[39]  J. Lown,,et al.  α-DNA-V. Parallel annealing, handedness and conformation of the duplex of the unnatural α-hexadeoxyribonucleotide α-[d(CpApTpGpCpG)] with its β-complement β-[d(GpTpApCpGpC)] deduced from high field 1H-NMR , 1987 .

[40]  C. Hélène,et al.  Oligo(alpha-deoxynucleotide)s covalently linked to intercalating agents: differential binding to ribo- and deoxyribopolynucleotides and stability towards nuclease digestion. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[41]  C. Paoletti,et al.  α-DNA II. Synthesis of unnatural α-anomeric oligodeoxyribonucleotides containing the four usual bases and study of their substrate activities for nucleases , 1987 .

[42]  W. Wechter,et al.  Preparation and Characterization of Oligonucleotides of D- and L-2’ Deoxyuridine , 1984 .

[43]  Wolfram Saenger,et al.  Principles of Nucleic Acid Structure , 1983 .