Approaches to open source 3-D printable probe positioners and micromanipulators for probe stations

Abstract Three types of highly-customizable open source probe positioning systems are evaluated: (a) mostly 3-D printed, (b) partially printed using OpenBeam kinematic constraints, and (c) a 3-level stack of low-cost commercial single axis micropositioners and some printed parts. All systems use digital distributed manufacturing to enable bespoke features, which can be fabricated with RepRap-class 3-D printer and easily accessible components. They are all flexible in material choice for custom components. The micropositioners can be set up for left-right use and flat or recessed configurations using either mechanical or magnetic mounting. All systems use a manual probe holder that can be customized and enable a quick swap probe system. System (a) is purchased for $100 or fabricated for 200 µm, (b) 40 µm and (c) 10 µm. A tradeoff is observed for 3-D printed percent between cost and accuracy. All systems provided substantial cost savings over proprietary products with similar functionality.

[1]  Joshua M. Pearce,et al.  Building Research Equipment with Free, Open-Source Hardware , 2012, Science.

[2]  Joshua M. Pearce,et al.  Open-Source Automated Mapping Four-Point Probe , 2017, Materials.

[3]  David Andrew Barry,et al.  Adaptable Imaging Package for Remote Vehicles , 2017 .

[4]  Daniel Güllmar,et al.  3D printing of MRI compatible components: why every MRI research group should have a low-budget 3D printer. , 2014, Medical engineering & physics.

[5]  G. Morlock,et al.  Open-Source-Based 3D Printing of Thin Silica Gel Layers in Planar Chromatography. , 2017, Analytical chemistry.

[6]  T. Pohida,et al.  3D-Printing for Analytical Ultracentrifugation , 2016, PloS one.

[7]  Alejandra Valencia,et al.  A 3D Printed Toolbox for Opto-Mechanical Components , 2016, PloS one.

[8]  Joshua M. Pearce.  Open-Source Lab: How to Build Your Own Hardware and Reduce Research Costs , 2013 .

[9]  Alicia Gibb,et al.  Building Open Source Hardware: DIY Manufacturing for Hackers and Makers , 2014 .

[10]  Charles Bell.  Delta Printer Hardware , 2015 .

[11]  Alexander M. Tothill,et al.  Fabrication and optimisation of a fused filament 3D-printed microfluidic platform , 2017 .

[12]  Joshua M. Pearce,et al.  Open-Source 3D-Printable Optics Equipment , 2013, PloS one.

[13]  Kara Brower,et al.  An Open-Source, Programmable Pneumatic Setup for Operation and Automated Control of Single- and Multi-Layer Microfluidic Devices. , 2018, HardwareX.

[14]  Joshua M. Pearce,et al.  Open-Source Wax RepRap 3-D Printer for Rapid Prototyping Paper-Based Microfluidics , 2016, Journal of laboratory automation.

[15]  Rhys Jones,et al.  RepRap – the replicating rapid prototyper , 2011, Robotica.

[16]  BowyerAdrian,et al.  3D Printing and Humanity's First Imperfect Replicator , 2014 .

[17]  Bethany C Gross,et al.  Evaluation of 3D printing and its potential impact on biotechnology and the chemical sciences. , 2014, Analytical chemistry.

[18]  Joshua M. Pearce,et al.  Open source laboratory sample rotator mixer and shaker , 2017, HardwareX.

[19]  Martín A. Zalazar,et al.  Open Source Quartz Crystal Microbalance with dissipation monitoring , 2016 .

[20]  Adrian Bowyer,et al.  RepRap: The Replicating Rapid Prototyper: Maximizing Customizability by Breeding the Means of Production , 2010 .

[21]  Joshua M. Pearce.  Emerging Business Models for Open Source Hardware , 2017 .

[22]  Jorge Bravo-Martínez.  Open source 3D-printed 1000 μL micropump , 2017 .

[23]  Aaron R Wheeler,et al.  Upon the Shoulders of Giants: Open-Source Hardware and Software in Analytical Chemistry. , 2017, Analytical chemistry.

[24]  Joshua M. Pearce,et al.  Free and Open Source 3-D Model Customizer for Websites to Democratize Design with OpenSCAD , 2017 .

[25]  P. Cochat,et al.  Et al , 2008, Archives de pediatrie : organe officiel de la Societe francaise de pediatrie.

[26]  Joshua M. Pearce,et al.  Compatibility of 3-D printed devices in cleanroom environments for semiconductor processing , 2019, Materials Science in Semiconductor Processing.

[27]  Bram Vanderborght,et al.  Overview of technologies for building robots in the classroom , 2013 .

[28]  James F Rusling,et al.  3D-Printed Fluidic Devices for Nanoparticle Preparation and Flow-Injection Amperometry Using Integrated Prussian Blue Nanoparticle-Modified Electrodes. , 2015, Analytical chemistry.

[29]  Joshua M. Pearce,et al.  General Design Procedure for Free and Open-Source Hardware for Scientific Equipment , 2017 .

[30]  Iain A. Anderson,et al.  3D printing for dielectric elastomers , 2014, Smart Structures.

[31]  Joshua M. Pearce,et al.  Chemical compatibility of fused filament fabrication-based 3-D printed components with solutions commonly used in semiconductor wet processing , 2018, Additive Manufacturing.

[32]  S. Acharya,et al.  Studying Electrical Conductivity Using a 3D Printed Four-Point Probe Station , 2017 .

[33]  Adam Spencer,et al.  Open source and DIY hardware for DNA nanotechnology labs. , 2015, Journal of biological methods.

[34]  H. Goicoechea,et al.  Open-Source Assisted Laboratory Automation through Graphical User Interfaces and 3D Printers: Application to Equipment Hyphenation for Higher-Order Data Generation. , 2017, Analytical chemistry.

[35]  Lucia L. Prieto-Godino,et al.  Open Labware: 3-D Printing Your Own Lab Equipment , 2015, PLoS biology.