Primary Epitopes of Chicken Egg Yolk Antibodies to Peptidophosphogalactomannan

ABSTRACT Egg yolks from hens immunized with peptidophosphogalactomannan (pPGalManii), which contains 10 phosphocholine diester residues and is secreted by Penicillium fellutanum, contain antibodies against 5-O-β-d-galactofuranosyl epitopes. These epitopes were the only significant determinants in pPGalManii. Approximately 60-fold less pPGalManii (1.6 μM galactofuran chains) was required for 50% inhibition than galactofurano-oligosaccharides or pPGalMan containing two galactofuranosyl residues per chain.

[1]  J. Meis,et al.  Specificity of a sandwich enzyme-linked immunosorbent assay for detecting Aspergillus galactomannan , 1997, Journal of clinical microbiology.

[2]  J. Latgé,et al.  A new sensitive sandwich enzyme-linked immunosorbent assay to detect galactofuran in patients with invasive aspergillosis , 1995, Journal of clinical microbiology.

[3]  J. Latgé,et al.  Chemical and immunological characterization of the extracellular galactomannan of Aspergillus fumigatus , 1994, Infection and immunity.

[4]  A. Descoteaux,et al.  The lipophosphoglycan of Leishmania parasites. , 1992, Annual review of microbiology.

[5]  P. Brennan,et al.  Structure, function and biogenesis of the cell envelope of mycobacteria in relation to bacterial physiology, pathogenesis and drug resistance; some thoughts and possibilities arising from recent structural information. , 1991, Research in microbiology.

[6]  C. Unkefer,et al.  The 5-O-beta-D-galactofuranosyl-containing peptidophosphogalactomannan of Penicillium charlesii. Characterization of the mannan by 13C NMR spectroscopy. , 1990, The Journal of biological chemistry.

[7]  B. Zingales,et al.  Terminal β‐d‐galactofuranosyl epitopes recognized by antibodies that inhibit Trypanosoma cruzi internalization into mammalian cells , 1989 .

[8]  G. Veeneman,et al.  (1----5)-linked beta-D-galactofuranosides are immunodominant in extracellular polysaccharides of Penicillium and Aspergillus species. , 1988, Molecular immunology.

[9]  H. Aspöck,et al.  Purification of egg yolk immunoglobulins. A two-step procedure using hydrophobic interaction chromatography and gel filtration. , 1988, Journal of immunological methods.

[10]  K. H. Kang,et al.  Differentiation of ruminal bacterial species by enzyme-linked immunosorbent assay using egg yolk antibodies from immunized chicken hens , 1988, Applied and environmental microbiology.

[11]  M. Ferguson,et al.  Cell-surface anchoring of proteins via glycosyl-phosphatidylinositol structures. , 1988, Annual review of biochemistry.

[12]  J. Gander,et al.  Variations in phosphoryl substituents in extracellular peptidophosphogalactomannans fromPenicillium charlesii G. Smith , 1985 .

[13]  J. Bennett,et al.  Galactofuranosyl groups are immunodominant in Aspergillus fumigatus galactomannan. , 1985, Molecular immunology.

[14]  J. Bennett,et al.  Capsular polysaccharides of Cryptococcus neoformans. , 1984, Reviews of infectious diseases.

[15]  G. Fincher,et al.  Arabinogalactan-Proteins: Structure, Biosynthesis, and Function , 1983 .

[16]  C. Unkefer,et al.  The 5-O-beta-D-galactofuranosyl-containing glycopeptide from Penicillium charlesii. Identification of phosphocholine attached to C-6 of mannopyranosyl residues of the mannan region. , 1982, The Journal of biological chemistry.

[17]  P. Gorin,et al.  Cell constituents of mycelia and conidia of Aspergillus fumigatus , 1981 .

[18]  M. Bar-joseph,et al.  Hen egg yolk as a source of antiviral antibodies in the enzyme-linked immunosorbent assay (ELISA): a comparison of two plant viruses. , 1980, Journal of Virological Methods.

[19]  M. V. Van Regenmortel,et al.  Isolation of viral IgY antibodies from yolks of immunized hens. , 1980, Immunological communications.

[20]  E. Reiss,et al.  Galactomannan antigenemia in invasive aspergillosis , 1979, Infection and immunity.

[21]  J. Gander,et al.  Extracellular exo-beta-galactofuranosidase from Penicillium charlesii: isolation, purification, and properties. , 1977, The Journal of biological chemistry.

[22]  S. Suzuki,et al.  Serologic cross-reactivity of the D-galacto-D-mannans isolated from several pathogenic fungi against anti-Hormodendrum pedrosoi serum. , 1975, Carbohydrate research.

[23]  L. Drewes,et al.  The 5-O-beta-D-galactofuranosyl-containing exocellular glycopeptide of Penicillium charlesii. Characterization of the phosphogalactomannan. , 1974, The Journal of biological chemistry.

[24]  L. Drewes,et al.  The 5-O-beta-D-galactofuranosyl-containing exocellular glycopeptide of Penicillium charlesii. Occurrence of ethanolamine and partial characterization of the peptide portion and the carbohydrate-peptide linkage. , 1974, The Journal of biological chemistry.

[25]  J. Gander.  Fungal cell wall glycoproteins and peptido-polysaccharides. , 1974, Annual review of microbiology.

[26]  J. Gander,et al.  Immunological investigations of Penicillium. II. Primary binding of glycopeptides and glycopeptide derivatives to specific antibodies. , 1973, Immunochemistry.

[27]  L. Young,et al.  Aspergillosis complicating neoplastic disease. , 1973, The American journal of medicine.

[28]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[29]  J. Preston,et al.  Immunological investigations of Penicillium. I. Serological reactivities of exocellular polysaccharides produced by six Penicillium species. , 1970, Canadian Journal of Microbiology (print).

[30]  J. Preston,et al.  Isolation and partial characterization of the exocellular polysaccharides of Penicillium charlesii. 3. Heterogeneity in size and composition of high molecular weight exocellular polysaccharides. , 1969, Archives of biochemistry and biophysics.

[31]  J. Preston,et al.  Isolation and partial characterization of the exocellular polysaccharides of Penicillium charlesii. II. The occurrence of phosphate groups in high molecular weight polysaccharides. , 1969, Archives of biochemistry and biophysics.

[32]  The 5-O-@-D-Galactofuranosyl-containing Glycopeptide of Penicillium OCCURRENCE OF ETHANOLAMINE AND PARTIAL CHARACTERIZATION OF THE PEPTIDE PORTION AND THE CARBOHYDRATE-PEPTIDE LINKAGE* , 2022 .