Hypothalamic endogenous noradrenaline and thermoregulation in the cat and rabbit

1. The imino‐dibenzyl drugs, imipramine and desipramine, which inhibit the uptake by neurones of noradrenaline, were injected into the lateral cerebral ventricles of cats and rabbits: changes in body temperature resulted which were different for the two species, but nevertheless closely resembled those following intraventricular injection of relatively large quantities of exogenous noradrenaline.

[1]  W. I. Cranston,et al.  Evidence concerning the effects of endogenous noradrenaline upon body temperature in cats and rabbits. , 1971, The Journal of physiology.

[2]  M. Simmonds,et al.  Effect of environmental temperature on the turnover of noradrenaline in hypothalamus and other areas of rat brain , 1969, The Journal of physiology.

[3]  R H Cox,et al.  A method for the determination of serotonin and norepinephrine in discrete areas of rat brain. , 1968, International journal of neuropharmacology.

[4]  K. Taylor,et al.  The fluorometric assay of catecholamines and related compounds: improvements and extensions to the hydroxyindole technique. , 1968, Analytical biochemistry.

[5]  L. Iversen,et al.  REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN–II , 1966, Journal of neurochemistry.

[6]  L. Iversen,et al.  Regional studies of catecholamines in the rat brain. 3. Subcellullar distribution of endogenous and exogenous catecholamines in various brain regions. , 1966, Biochemical pharmacology.

[7]  K. Fuxe,et al.  Mapping out of catecholamine and 5-hydroxytryptamine neurons innervating the telencephalon and diencephalon. , 1965, Life sciences.

[8]  L. Iversen Inhibition of noradrenaline uptake by drugs , 1965, Advances in drug research.

[9]  A. Sjoerdsma,et al.  BLOCKADE OF ENDOGENOUS NOREPINEPHRINE SYNTHESIS BY ALPHA-METHYL-TYROSINE, AN INHIBITOR OF TYROSINE HYDROXYLASE. , 1965, The Journal of pharmacology and experimental therapeutics.

[10]  R. D. Myers,et al.  Effects on temperature of amines injected into the cerebral ventricles. A new concept of temperature regulation , 1964, The Journal of physiology.

[11]  W. Feldberg,et al.  A New Concept of Temperature Regulation by Amines in the Hypothalamus , 1963, Nature.

[12]  M. Vogt The concentration of sympathin in different parts of the central nervous system under normal conditions and after the administration of drugs , 1954, The Journal of physiology.