Caveolin-1 enhances brain metastasis of non-small cell lung cancer, potentially in association with the epithelial-mesenchymal transition marker SNAIL

[1]  I. Nabi,et al.  Reciprocal regulation of the Cadherin-11/Stat3 axis by caveolin-1 in mouse fibroblasts and lung carcinoma cells. , 2018, Biochimica et biophysica acta. Molecular cell research.

[2]  M. Mazzone,et al.  Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis , 2017, Cell reports.

[3]  Wei-Chung Cheng,et al.  EFHD2 promotes epithelial-to-mesenchymal transition and correlates with postsurgical recurrence of stage I lung adenocarcinoma , 2017, Scientific Reports.

[4]  M. Papotti,et al.  Caveolin 1 expression favors tumor growth and is associated with poor survival in primary lung adenocarcinomas , 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

[5]  M. Tsuboi,et al.  Clinicopathological significance of caveolin-1 expression by cancer-associated fibroblasts in lung adenocarcinoma , 2017, Journal of Cancer Research and Clinical Oncology.

[6]  I. Jang,et al.  Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma , 2017, Oncotarget.

[7]  I. Ng,et al.  Mechanisms through Which Hypoxia-Induced Caveolin-1 Drives Tumorigenesis and Metastasis in Hepatocellular Carcinoma. , 2016, Cancer research.

[8]  Hyung-Seok Kim,et al.  Regulation of Caveolin-1 Expression Determines Early Brain Edema After Experimental Focal Cerebral Ischemia , 2016, Stroke.

[9]  A. Nicholson,et al.  Introduction to The 2015 World Health Organization Classification of Tumors of the Lung, Pleura, Thymus, and Heart. , 2015, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[10]  M. Papotti,et al.  CAVEOLIN-1 expression in brain metastasis from lung cancer predicts worse outcome and radioresistance, irrespective of tumor histotype , 2015, Oncotarget.

[11]  Yong Li,et al.  Identification of Commonly Dysregulated Genes in Non-small-cell Lung Cancer by Integrated Analysis of Microarray Data and qRT-PCR Validation , 2015, Lung.

[12]  S. Gomez,et al.  US lung cancer trends by histologic type , 2015, Cancer.

[13]  Shin Jung,et al.  KITENIN promotes glioma invasiveness and progression, associated with the induction of EMT and stemness markers , 2014, Oncotarget.

[14]  A. Marcus,et al.  Aberrant Promoter Methylation of Caveolin-1 Is Associated with Favorable Response to Taxane-Platinum Combination Chemotherapy in Advanced NSCLC , 2014, PloS one.

[15]  D. R. Lewis,et al.  US lung cancer trends by histologic type , 2014, Cancer.

[16]  Pengyuan Yang,et al.  CAV1 Promotes HCC Cell Progression and Metastasis through Wnt/β-Catenin Pathway , 2014, PloS one.

[17]  Xi Chen,et al.  Loss of Stromal Caveolin-1 Expression: A Novel Tumor Microenvironment Biomarker That Can Predict Poor Clinical Outcomes for Pancreatic Cancer , 2014, PloS one.

[18]  J. Xu,et al.  Cavin-1 is essential for the tumor-promoting effect of caveolin-1 and enhances its prognostic potency in pancreatic cancer , 2014, Oncogene.

[19]  Xiao-jun Zhou,et al.  [Correlation of caveolin-1 expression with clinicopathologic features and prognosis in patients with lung adenocarcinoma]. , 2014, Zhonghua bing li xue za zhi = Chinese journal of pathology.

[20]  B. Zhou,et al.  The Role of Snail in EMT and Tumorigenesis. , 2013, Current cancer drug targets.

[21]  T. Thompson,et al.  Loss of caveolin‐1 in prostate cancer stroma correlates with reduced relapse‐free survival and is functionally relevant to tumour progression , 2013, The Journal of pathology.

[22]  F. Beca,et al.  Loss of caveolin-1 and gain of MCT4 expression in the tumor stroma: Key events in the progression from an in situ to an invasive breast carcinoma , 2013, Cell cycle.

[23]  Li-ke Yu,et al.  Expression of caveolin-1 is correlated with disease stage and survival in lung adenocarcinomas , 2011, Oncology reports.

[24]  F. Sotgia,et al.  Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition , 2011, Cell cycle.

[25]  F. Sotgia,et al.  Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment , 2011, Breast Cancer Research.

[26]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[27]  Hong Chen,et al.  Differential expression and function of the caveolin-1 gene in non-small cell lung carcinoma. , 2011, Oncology reports.

[28]  R. Senetta,et al.  Epidermal growth factor receptor and caveolin-1 coexpression identifies adult supratentorial ependymomas with rapid unfavorable outcomes. , 2011, Neuro-oncology.

[29]  J. Lee,et al.  Snail Promotes CXCR2 LigandDependent Tumor Progression in NonSmall Cell Lung Carcinoma , 2009, Clinical Cancer Research.

[30]  G. Scagliotti,et al.  Caveolin‐1 expression in lung carcinoma varies according to tumour histotype and is acquired de novo in brain metastases , 2009, Histopathology.

[31]  Raghu Kalluri,et al.  The basics of epithelial-mesenchymal transition. , 2009, The Journal of clinical investigation.

[32]  R. Soffietti,et al.  Caveolin 1 Expression Independently Predicts Shorter Survival in Oligodendrogliomas , 2009, Journal of neuropathology and experimental neurology.

[33]  O. Sagol,et al.  Differential expression of Caveolin-1 in hepatocellular carcinoma: correlation with differentiation state, motility and invasion , 2009, BMC Cancer.

[34]  S. Wiseman,et al.  Caveolin-1 in tumor progression: the good, the bad and the ugly , 2008, Cancer and Metastasis Reviews.

[35]  B. Goh,et al.  Correlation of RRM1 promoter region single nucleotide polymorphisms (SNPs) with response and outcome in breast cancer patients treated with gemcitabine-based chemotherapy , 2008 .

[36]  Kelly M. Bailey,et al.  Caveolin-1 Up-regulation during Epithelial to Mesenchymal Transition Is Mediated by Focal Adhesion Kinase* , 2008, Journal of Biological Chemistry.

[37]  C. Waterman-Storer,et al.  Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases , 2007, The Journal of cell biology.

[38]  David S. Park,et al.  Caveolin-1 and regulation of cellular cholesterol homeostasis. , 2006, American journal of physiology. Heart and circulatory physiology.

[39]  K. Moon,et al.  Expression of caveolin-1 in pleomorphic carcinoma of the lung is correlated with a poor prognosis. , 2005, Anticancer research.

[40]  M. Nieto,et al.  The Snail genes as inducers of cell movement and survival: implications in development and cancer , 2005, Development.

[41]  V. Castranova,et al.  Loss of Caveolin-1 Polarity Impedes Endothelial Cell Polarization and Directional Movement* , 2005, Journal of Biological Chemistry.

[42]  S. Okushiba,et al.  Difference of caveolin-1 expression pattern in human lung neoplastic tissue. Atypical adenomatous hyperplasia, adenocarcinoma and squamous cell carcinoma. , 2004, Cancer letters.

[43]  M. Lisanti,et al.  Role of caveolae and caveolins in health and disease. , 2004, Physiological reviews.

[44]  J. Minna,et al.  Different Roles for Caveolin-1 in the Development of Non-Small Cell Lung Cancer versus Small Cell Lung Cancer , 2004, Cancer Research.

[45]  M. Lisanti,et al.  Expression of caveolin-1 and caveolin-2 in urothelial carcinoma of the urinary bladder correlates with tumor grade and squamous differentiation. , 2003, American journal of clinical pathology.

[46]  A. Twijnstra,et al.  Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma , 2002, Cancer.

[47]  S. Okushiba,et al.  Overexpression of caveolin‐1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage , 2002, Cancer.

[48]  M Dietel,et al.  Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene. , 2001, The American journal of pathology.

[49]  M. Ittmann,et al.  Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer. , 2001, Cancer research.

[50]  A. Quest,et al.  Caveolin-1 levels are down-regulated in human colon tumors, and ectopic expression of caveolin-1 in colon carcinoma cell lines reduces cell tumorigenicity. , 2000, Cancer research.

[51]  P. Levendag,et al.  Identification of prognostic factors in patients with brain metastases: a review of 1292 patients. , 1999, International journal of radiation oncology, biology, physics.

[52]  T. Seya,et al.  Expression of caveolin-1 in human T cell leukemia cell lines. , 1998, Biochemical and biophysical research communications.

[53]  M. Lisanti,et al.  Caveolins, a Family of Scaffolding Proteins for Organizing “Preassembled Signaling Complexes” at the Plasma Membrane* , 1998, The Journal of Biological Chemistry.

[54]  E. Knights.  Metastatic tumors of the brain and their relation to primary and secondary pulmonary cancer , 1954, Cancer.

[55]  A. Jemal,et al.  Cancer statistics, 2019 , 2019, CA: a cancer journal for clinicians.

[56]  Arunkumar Krishnan,et al.  Caveolin-1 promotes gastric cancer progression by up-regulating epithelial to mesenchymal transition by crosstalk of signalling mechanisms under hypoxic condition. , 2014, European journal of cancer.

[57]  Chih-Hsin Yang,et al.  Caveolin-1 expression is significantly associated with drug resistance and poor prognosis in advanced non-small cell lung cancer patients treated with gemcitabine-based chemotherapy. , 2008, Lung cancer.

[58]  F. Sotgia,et al.  Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness. , 2006, The American journal of pathology.

[59]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[60]  N. Dubrawsky.  Cancer statistics , 1989, CA: a cancer journal for clinicians.