Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.
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M. Wigler | D. Bar-Sagi | J. Schlessinger | J. Camonis | L. Van Aelst | N. Gale | P. Chardin | L. Aelst
[1] P Cicchetti,et al. Identification of a ten-amino acid proline-rich SH3 binding site. , 1993, Science.
[2] R. Medema,et al. Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras , 1993, Molecular and cellular biology.
[3] Sheila M. Thomas,et al. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases , 1992, Nature.
[4] S. Schreiber,et al. Solution structure of the SH3 domain of Src and identification of its ligand-binding site. , 1992, Science.
[5] D. Lowy,et al. Isolation of multiple mouse cDNAs with coding homology to Saccharomyces cerevisiae CDC25: identification of a region related to Bcr, Vav, Dbl and CDC24. , 1992, The EMBO journal.
[6] T. Pawson,et al. SH2 and SH3 domains: From structure to function , 1992, Cell.
[7] A. Ullrich,et al. The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling , 1992, Cell.
[8] D. Baltimore,et al. Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho. , 1992, Science.
[9] Lowy,et al. Mechanistic aspects of signaling through Ras in NIH 3T3 cells. , 1992, Science.
[10] B. Neel,et al. Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21 , 1992, Nature.
[11] D. Bowtell,et al. Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[12] H. Kung,et al. Nerve growth factor stimulation of the Ras-guanine nucleotide exchange factor and GAP activities. , 1992, Science.
[13] E. Martegani,et al. Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator. , 1992, The EMBO journal.
[14] B. Futcher,et al. The Cln3‐Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. , 1992, The EMBO journal.
[15] H. Horvitz,et al. C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains , 1992, Nature.
[16] J. Blenis,et al. ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK , 1992, Cell.
[17] Sheila M. Thomas,et al. Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases , 1992, Cell.
[18] J. Downward. Regulatory mechanisms for ras proteins , 1992, BioEssays : news and reviews in molecular, cellular and developmental biology.
[19] R. Treisman,et al. Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element , 1992, Cell.
[20] G. Rubin,et al. Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase , 1991, Cell.
[21] S. Fields,et al. The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[22] H. Stunnenberg,et al. Rapid and efficient purification of native histidine-tagged protein expressed by recombinant vaccinia virus. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[23] D. Bar-Sagi,et al. Association of p21ras with cellular polypeptides. , 1991, The Journal of biological chemistry.
[24] J. Broach,et al. The CDC25 protein of Saccharomyces cerevisiae promotes exchange of guanine nucleotides bound to ras , 1991, Molecular and cellular biology.
[25] R. Cerione,et al. Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[26] J B Gibbs,et al. Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP). , 1990, The Journal of biological chemistry.
[27] G. Cooper,et al. Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells , 1990, Molecular and cellular biology.
[28] G. Cooper,et al. Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells , 1990, Molecular and cellular biology.
[29] P. Warne,et al. Stimulation of p21ras upon T-cell activation , 1990, Nature.
[30] M. Endo,et al. Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[31] S. Fields,et al. A novel genetic system to detect proteinprotein interactions , 1989, Nature.
[32] A. Ullrich,et al. Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing , 1987, Cell.
[33] J. Mallet,et al. A single human gene encoding multiple tyrosine hydroxylases with different predicted functional characteristics , 1987, Nature.
[34] M. Wigler,et al. The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway , 1987, Cell.
[35] L. C. Robinson,et al. CDC25: a component of the RAS-adenylate cyclase pathway in Saccharomyces cerevisiae. , 1987, Science.
[36] Mark R. Smith,et al. Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells , 1985, Nature.