Serologic changes in pneumoconiosis and progressive massive fibrosis of coal workers.

Serum from 109 coal workers with simple pneumoconiosis, 114 with progressive massive fibrosis, and 130 with normal chest radiographics as control subjects was examined for rheumatoid and antinuclear factors, and antibodies against both native human IgG and Mycobacterium tuberculosis. A significantly greater prevalence of autoantibodies was observed in subjects with pneumoconiosis than in control subjects; however, a rheumatoid factor prevalence of 16% with observed inthe control subjects. No serologic differences were observed between subjects with simple pneumoconiosis and those with progressive massive fibrosis.

[1]  J. Elliott,et al.  Correlation of gm allotype with the incidience of anti-IgG antibody in coal workers' pneumoconiosis. , 1980, Clinical immunology and immunopathology.

[2]  A. Nicholls.  A serodiagnostic test for tuberculosis. , 1975, Journal of clinical pathology.

[3]  C. Soutar,et al.  Circulating Antinuclear Antibody and Rheumatoid Factor in Coal Pneumoconiosis , 1974, British medical journal.

[4]  H. Polesky,et al.  The Risk of Immunization to IgG Following Rh Immune Globulin Therapy , 1974, Transfusion.

[5]  R. Naeye.  TYPES OF FIBROSIS IN COAL WORKERS' PNEUMOCONIOSIS * , 1972, Annals of the New York Academy of Sciences.

[6]  R. Naeye,et al.  Rank of coal and coal workers pneumoconiosis. , 1971, The American review of respiratory disease.

[7]  J. Gough.  Fibrosis in coal workers. , 1968, Archives of environmental health.

[8]  B. Permis.  Immunological Reactions and Pulmonary Dust Disease. , 1966 .

[9]  D. Rivers,et al.  The Prevalence of Tuberculosis at Necropsy in Progressive Massive Fibrosis of Coalworkers , 1957, British journal of industrial medicine.

[10]  A. Mclaughlin,et al.  The new international classification of radiographs of the pneumoconioses. , 1962, The Annals of occupational hygiene.