Pro-myogenic small molecules revealed by a chemical screen on primary muscle stem cells
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L. Rubin | Sean M. Buchanan | A. Wagers | F. Price | J. Schneider | Mohammadsharif Tabebordbar | A. Castiglioni | M. Hayhurst | A. Gee | Mark N. Matyas | Joel S. Schneider
[1] Xiaobin Zheng,et al. Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice , 2019, Nature Metabolism.
[2] L. Mendoza. Clinical development of RET inhibitors in RET-rearranged non-small cell lung cancer: Update , 2018, Oncology reviews.
[3] Aaron M. Beedle,et al. Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration , 2018, The Journal of clinical investigation.
[4] Yu Xin Wang,et al. Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength , 2017, Proceedings of the National Academy of Sciences.
[5] B. Olwin,et al. Regulation of skeletal muscle stem cells by fibroblast growth factors , 2017, Developmental dynamics : an official publication of the American Association of Anatomists.
[6] T. Rando,et al. HGFA Is an Injury-Regulated Systemic Factor that Induces the Transition of Stem Cells into GAlert. , 2017, Cell reports.
[7] C. Banerji,et al. Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy , 2016, eLife.
[8] Albert E. Almada,et al. Established cell surface markers efficiently isolate highly overlapping populations of skeletal muscle satellite cells by fluorescence-activated cell sorting , 2016, Skeletal Muscle.
[9] Albert E. Almada,et al. Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease , 2016, Nature Reviews Molecular Cell Biology.
[10] G. Drewes,et al. Discovery of Novel Small Molecules that Activate Satellite Cell Proliferation and Enhance Repair of Damaged Muscle. , 2016, ACS chemical biology.
[11] Sara Zarei,et al. A comprehensive review of amyotrophic lateral sclerosis , 2015, Surgical neurology international.
[12] Yu Xin Wang,et al. Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division , 2015, Nature Medicine.
[13] Barbora Malecova,et al. STAT3 signaling controls satellite cell expansion and skeletal muscle repair , 2014, Nature Medicine.
[14] Nicolas A. Dumont,et al. Inhibition of JAK/STAT signaling stimulates adult satellite cell function , 2014, Nature Medicine.
[15] Melinda J. Cromie,et al. mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert , 2014, Nature.
[16] A. Wagers,et al. Isolation of Progenitors that Exhibit Myogenic/Osteogenic Bipotency In Vitro by Fluorescence-Activated Cell Sorting from Human Fetal Muscle , 2014, Stem cell reports.
[17] R. Kothary,et al. Myogenic program dysregulation is contributory to disease pathogenesis in spinal muscular atrophy , 2014, Human molecular genetics.
[18] John K. Hall,et al. P38 MAPK signaling underlies a cell autonomous loss of stem cell self-renewal in aged skeletal muscle , 2014, Nature Medicine.
[19] S. Delp,et al. Rejuvenation of the aged muscle stem cell population restores strength to injured aged muscles , 2014, Nature Medicine.
[20] M. Levis,et al. FLT3 tyrosine kinase inhibitors in acute myeloid leukemia: clinical implications and limitations , 2014, Leukemia & lymphoma.
[21] M. Kyba,et al. High-throughput screening identifies inhibitors of DUX4-induced myoblast toxicity , 2014, Skeletal Muscle.
[22] A. Wagers,et al. Isolation of Progenitors that Exhibit Myogenic/Osteogenic Bipotency In Vitro by Fluorescence-Activated Cell Sorting from Human Fetal Muscle , 2014, Stem cell reports.
[23] L. Zon,et al. A Zebrafish Embryo Culture System Defines Factors that Promote Vertebrate Myogenesis across Species , 2013, Cell.
[24] L. Rubin,et al. A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS. , 2013, Cell stem cell.
[25] M. Rudnicki,et al. Isolation and Culture of Individual Myofibers and their Satellite Cells from Adult Skeletal Muscle , 2013, Journal of visualized experiments : JoVE.
[26] L. Rubin,et al. A cell-autonomous defect in skeletal muscle satellite cells expressing low levels of survival of motor neuron protein. , 2012, Developmental biology.
[27] M. Rudnicki,et al. Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis. , 2012, Molecular cell.
[28] M. A. Basson,et al. The aged niche disrupts muscle stem cell quiescence , 2012, Nature.
[29] Jong-Sun Kang,et al. Gas1 cooperates with Cdo and promotes myogenic differentiation via activation of p38MAPK. , 2011, Cellular signalling.
[30] Christoph Lepper,et al. An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration , 2011, Development.
[31] B. Malissen,et al. Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration , 2011, Development.
[32] J. Steen,et al. A screen for regulators of survival of motor neuron protein levels. , 2011, Nature chemical biology.
[33] J. Spitsbergen,et al. Cholinergic neurons regulate secretion of glial cell line-derived neurotrophic factor by skeletal muscle cells in culture , 2011, Brain Research.
[34] J. Spitsbergen,et al. Glial cell line-derived neurotrophic factor protein content in rat skeletal muscle is altered by increased physical activity in vivo and in vitro , 2011, Neuroscience.
[35] D. Glass,et al. Molecular mechanisms and treatment options for muscle wasting diseases. , 2011, Annual review of pharmacology and toxicology.
[36] S. Thrun,et al. Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture , 2010, Science.
[37] G. Shefer,et al. The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny. , 2010, Developmental biology.
[38] Michael A. Rudnicki,et al. Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis , 2010, Nature Cell Biology.
[39] D. Schaffer,et al. Relative roles of TGF-β1 and Wnt in the systemic regulation and aging of satellite cell responses , 2009, Aging cell.
[40] D. Ingber,et al. Carbon metabolism-mediated myogenic differentiation , 2009, Nature chemical biology.
[41] P. Zarrinkar,et al. AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). , 2009, Blood.
[42] Shahragim Tajbakhsh,et al. Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates. , 2009, Developmental cell.
[43] M. Rudnicki,et al. Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells. , 2009, Cell stem cell.
[44] A. Wagers,et al. Highly Efficient, Functional Engraftment of Skeletal Muscle Stem Cells in Dystrophic Muscles , 2008, Cell.
[45] Jeanne Shen,et al. A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. , 2008, Cell stem cell.
[46] Christian von Mering,et al. STITCH: interaction networks of chemicals and proteins , 2007, Nucleic Acids Res..
[47] A. Partin,et al. Preclinical and clinical studies with the multi-kinase inhibitor CEP-701 as treatment for prostate cancer demonstrate the inadequacy of PSA response as a primary endpoint , 2007, Cancer biology & therapy.
[48] M. Rudnicki,et al. Asymmetric Self-Renewal and Commitment of Satellite Stem Cells in Muscle , 2007, Cell.
[49] K. Mills,et al. The effects of lestaurtinib (CEP701) and PKC412 on primary AML blasts: the induction of cytotoxicity varies with dependence on FLT3 signaling in both FLT3-mutated and wild-type cases. , 2006, Blood.
[50] Charlotte Collins,et al. Direct Isolation of Satellite Cells for Skeletal Muscle Regeneration , 2005, Science.
[51] A. Petrie,et al. Stem Cell Function, Self-Renewal, and Behavioral Heterogeneity of Cells from the Adult Muscle Satellite Cell Niche , 2005, Cell.
[52] Richard Clark,et al. A phase 2 trial of the FLT3 inhibitor lestaurtinib (CEP701) as first-line treatment for older patients with acute myeloid leukemia not considered fit for intensive chemotherapy. , 2004, Blood.
[53] I. Weissman,et al. Isolation of Adult Mouse Myogenic Progenitors Functional Heterogeneity of Cells within and Engrafting Skeletal Muscle , 2004, Cell.
[54] T. Partridge,et al. Muscle satellite cells adopt divergent fates , 2004, The Journal of cell biology.
[55] H. Kantarjian,et al. Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia. , 2004, Blood.
[56] C. Strock,et al. CEP-701 and CEP-751 inhibit constitutively activated RET tyrosine kinase activity and block medullary thyroid carcinoma cell growth. , 2003, Cancer research.
[57] B. Smith,et al. A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo. , 2002, Blood.
[58] Mart Saarma,et al. The GDNF family: Signalling, biological functions and therapeutic value , 2002, Nature Reviews Neuroscience.
[59] A. Emery,et al. The muscular dystrophies , 2002, The Lancet.
[60] Irving L. Weissman,et al. Physiological Migration of Hematopoietic Stem and Progenitor Cells , 2001, Science.
[61] M. Rudnicki,et al. Pax7 Is Required for the Specification of Myogenic Satellite Cells , 2000, Cell.
[62] R. Allen,et al. Skeletal muscle satellite cell proliferation in response to members of the fibroblast growth factor family and hepatocyte growth factor , 1999, Journal of cellular physiology.
[63] A. Musarò,et al. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[64] Hidenori Suzuki,et al. Prominent expression of glial cell line–derived neurotrophic factor in human skeletal muscle , 1998, The Journal of comparative neurology.
[65] I. Nonaka,et al. Up-regulation of glial cell line-derived neurotrophic factor (GDNF) expression in regenerating muscle fibers in neuromuscular diseases , 1998, Neuroscience Letters.
[66] P Gruss,et al. Pax genes and their roles in cell differentiation and development. , 1996, Current opinion in cell biology.
[67] B. Ponder,et al. GDNF signalling through the Ret receptor tyrosine kinase , 1996, Nature.
[68] B. Riley,et al. Role of FGFs in skeletal muscle and limb development , 1994, Molecular reproduction and development.
[69] K. Moore,et al. X chromosome-linked muscular dystrophy (mdx) in the mouse. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[70] E. Schultz,et al. Satellite cells are mitotically quiescent in mature mouse muscle: an EM and radioautographic study. , 1978, The Journal of experimental zoology.
[71] Richard Bischoff,et al. Regeneration of single skeletal muscle fibers in vitro , 1975, The Anatomical record.
[72] A. Mauro. SATELLITE CELL OF SKELETAL MUSCLE FIBERS , 1961, The Journal of biophysical and biochemical cytology.