Adjuvant radiation therapy is associated with better oncological outcome compared with salvage radiation therapy in patients with pN1 prostate cancer treated with radical prostatectomy

To analyse the comparative effectiveness of no treatment (NT) or salvage radiation therapy (sRT) at biochemical recurrence (BCR) vs adjuvant radiation therapy (aRT) in patients with lymph node (LN)‐positive prostate cancer (PCa) after radical prostatectomy (RP).

[1]  A. Haese*,et al.  External validation of the CAPRA-S score to predict biochemical recurrence, metastasis and mortality after radical prostatectomy in a European cohort. , 2015, The Journal of urology.

[2]  Cesare Cozzarini,et al.  Impact of adjuvant radiotherapy on survival of patients with node-positive prostate cancer. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[3]  F. Burkhard,et al.  Removal of limited nodal disease in patients undergoing radical prostatectomy: long-term results confirm a chance for cure. , 2014, The Journal of urology.

[4]  S. Stampf Stratification and matching by the propensity score , 2014 .

[5]  T. H. van der Kwast,et al.  EAU guidelines on prostate cancer. part 1: screening, diagnosis, and local treatment with curative intent-update 2013. , 2014, European urology.

[6]  P. Scardino,et al.  Long-term outcomes of patients with lymph node metastasis treated with radical prostatectomy without adjuvant androgen-deprivation therapy. , 2014, European urology.

[7]  F. Montorsi,et al.  Extended pelvic lymph node dissection in prostate cancer: a 20-year audit in a single center. , 2013, Annals of oncology : official journal of the European Society for Medical Oncology.

[8]  F. Montorsi,et al.  Early salvage radiation therapy does not compromise cancer control in patients with pT3N0 prostate cancer after radical prostatectomy: results of a match-controlled multi-institutional analysis. , 2012, European urology.

[9]  A. Haese*,et al.  Full functional-length urethral sphincter preservation during radical prostatectomy. , 2011, European urology.

[10]  U. Capitanio,et al.  Combination of adjuvant hormonal and radiation therapy significantly prolongs survival of patients with pT2-4 pN+ prostate cancer: results of a matched analysis. , 2011, European urology.

[11]  A. Haese*,et al.  Current technique of open intrafascial nerve-sparing retropubic prostatectomy. , 2009, European urology.

[12]  F. Fazio,et al.  Long-term follow-up of patients with prostate cancer and nodal metastases treated by pelvic lymphadenectomy and radical prostatectomy: the positive impact of adjuvant radiotherapy. , 2009, European urology.

[13]  S. Freedland,et al.  Role of androgen deprivation therapy for node-positive prostate cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[14]  D. Grignon,et al.  Androgen suppression plus radiation versus radiation alone for patients with stage D1/pathologic node-positive adenocarcinoma of the prostate: updated results based on national prospective randomized trial Radiation Therapy Oncology Group 85-31. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[15]  F. Montorsi,et al.  Role of postoperative radiotherapy after pelvic lymphadenectomy and radical retropubic prostatectomy: a single institute experience of 415 patients. , 2004, International Journal of Radiation Oncology, Biology, Physics.