The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling.

[1]  David Komander,et al.  Ubiquitin modifications , 2016, Cell Research.

[2]  Jinfeng Liu,et al.  Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation , 2015, Nature.

[3]  J Wade Harper,et al.  Quantifying ubiquitin signaling. , 2015, Molecular cell.

[4]  J. Inoue,et al.  Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity , 2015, Nature Structural &Molecular Biology.

[5]  J. Kanno,et al.  Ubiquitin acetylation inhibits polyubiquitin chain elongation , 2015, EMBO reports.

[6]  D. Komander,et al.  Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest) , 2015, Nature Protocols.

[7]  M. Rapé,et al.  Enhanced Protein Degradation by Branched Ubiquitin Chains , 2014, Cell.

[8]  J. Tinevez,et al.  TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures , 2014, The Journal of cell biology.

[9]  Nieves Peltzer,et al.  Ubiquitin in the immune system , 2013, EMBO reports.

[10]  Patrick G. A. Pedrioli,et al.  Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains , 2013, Proceedings of the National Academy of Sciences.

[11]  Hikaru Tsuchiya,et al.  The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification. , 2013, Biochemical and biophysical research communications.

[12]  W. Xu,et al.  Method to convert N-terminal glutamine to pyroglutamate for characterization of recombinant monoclonal antibodies. , 2013, Analytical biochemistry.

[13]  Kelly M. Thayer,et al.  Analyses of the effects of all ubiquitin point mutants on yeast growth rate. , 2013, Journal of molecular biology.

[14]  M. Rapé,et al.  The Ubiquitin Code , 2012, Annual review of biochemistry.

[15]  Ivan Dikic,et al.  Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions. , 2012, Annual review of biochemistry.

[16]  T. Mak,et al.  The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis , 2012, The Journal of experimental medicine.

[17]  J. Chen,et al.  Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation , 2011, Nature.

[18]  A. Musacchio,et al.  Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation , 2011, EMBO reports.

[19]  R. Kelley,et al.  Improved Quantitative Mass Spectrometry Methods for Characterizing Complex Ubiquitin Signals , 2010, Molecular & Cellular Proteomics.

[20]  V. Dixit,et al.  Signaling to NF-kappaB: regulation by ubiquitination. , 2010, Cold Spring Harbor perspectives in biology.

[21]  Noula Shembade,et al.  Inhibition of NF-κB Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes , 2010, Science.

[22]  H. Walczak,et al.  Faculty Opinions recommendation of A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. , 2009 .

[23]  Yusuke Sato,et al.  Structural basis for specific recognition of Lys 63‐linked polyubiquitin chains by NZF domains of TAB2 and TAB3 , 2009, The EMBO journal.

[24]  Kay Hofmann,et al.  Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain , 2009, Nature Structural &Molecular Biology.

[25]  Zhijian J. Chen,et al.  A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. , 2009, Molecular cell.

[26]  Christine Yu,et al.  Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies , 2008, Cell.

[27]  Steven P Gygi,et al.  Certain Pairs of Ubiquitin-conjugating Enzymes (E2s) and Ubiquitin-Protein Ligases (E3s) Synthesize Nondegradable Forked Ubiquitin Chains Containing All Possible Isopeptide Linkages* , 2007, Journal of Biological Chemistry.

[28]  Aaron Ciechanover,et al.  The polycomb protein Ring1B generates self atypical mixed ubiquitin chains required for its in vitro histone H2A ligase activity. , 2006, Molecular cell.

[29]  K. Helin,et al.  The Ubiquitin Ligase HectH9 Regulates Transcriptional Activation by Myc and Is Essential for Tumor Cell Proliferation , 2005, Cell.

[30]  Jun Qin,et al.  ARF-BP1/Mule Is a Critical Mediator of the ARF Tumor Suppressor , 2005, Cell.

[31]  Xiaodong Wang,et al.  Mule/ARF-BP1, a BH3-Only E3 Ubiquitin Ligase, Catalyzes the Polyubiquitination of Mcl-1 and Regulates Apoptosis , 2005, Cell.

[32]  Steven P Gygi,et al.  A proteomics approach to understanding protein ubiquitination , 2003, Nature Biotechnology.

[33]  C. Pickart,et al.  Distinct Functional Surface Regions on Ubiquitin* , 2001, The Journal of Biological Chemistry.

[34]  Zhijian J. Chen,et al.  Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain , 2000, Cell.

[35]  Alexander Varshavsky,et al.  The ubiquitin system. , 1998, Annual review of biochemistry.

[36]  I. Ota,et al.  A Proteolytic Pathway That Recognizes Ubiquitin as a Degradation Signal (*) , 1995, The Journal of Biological Chemistry.

[37]  V. Dixit,et al.  Deubiquitinases in the regulation of NF-κB signaling , 2011, Cell Research.

[38]  A. Ashworth,et al.  Supplemental Data The Structure of the CYLD USP Domain Explains Its Specificity for Lys 63-Linked Polyubiquitin and Reveals a B Box Module , 2008 .