Psychological measures of prenatal stress as predictors of infant temperament.

OBJECTIVE To examine, in a prospective study, whether maternal stress during pregnancy is related to infant temperament. METHOD Self-report data on various aspects of prenatal stress were collected from nulliparous women in early pregnancy. Infant temperament was measured at 3 and 8 months by direct observation and by parent report. RESULTS Complete data were available for 170 term-born infants. Pregnancy-specific anxiety explained 3.3% of the variance of attention regulation at 3 months. Perceived stress and pregnancy anxiety taken together explained 5% of the variance of attention regulation at 8 months. Perceived stress accounted for 8.2% of the variance of difficult behavior of the 3-month-old infant. All results were adjusted for covariates. CONCLUSIONS Increased maternal prenatal stress seems to be associated with temperamental variation of young infants and may be a risk factor for psychopathology later in life.

[1]  A. Huizink Prenatal stress and its effect on infant development , 2000 .

[2]  J. Kagan,et al.  Early childhood predictors of adult anxiety disorders , 1999, Biological Psychiatry.

[3]  J. Jacobson,et al.  Neurobehavioral effects of prenatal alcohol exposure at 26 months. , 1999, Neurotoxicology and teratology.

[4]  J. Passchier,et al.  Psychosocial predictors of low birthweight: a prospective study , 1999, British journal of obstetrics and gynaecology.

[5]  C A Sandman,et al.  Psychological adaptation and birth outcomes: the role of personal resources, stress, and sociocultural context in pregnancy. , 1999, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[6]  N. Bayley Bayley Scales of Infant Development , 1999 .

[7]  G. Lubach,et al.  Growth and development following prenatal stress exposure in primates: an examination of ontogenetic vulnerability. , 1999, Child development.

[8]  S. Landry,et al.  Effects of medical risk and socioeconomic status on the rate of change in cognitive and social development for low birth weight children. , 1997, Journal of clinical and experimental neuropsychology.

[9]  M. Weinstock Does Prenatal Stress Impair Coping and Regulation of Hypothalamic-Pituitary-Adrenal Axis? , 1997, Neuroscience & Biobehavioral Reviews.

[10]  A. Meier,et al.  The preterm prediction study: maternal stress is associated with spontaneous preterm birth at less than thirty-five weeks' gestation. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. , 1996, American journal of obstetrics and gynecology.

[11]  D L Newman,et al.  Behavioral observations at age 3 years predict adult psychiatric disorders. Longitudinal evidence from a birth cohort. , 1996, Archives of general psychiatry.

[12]  M. Le Moal,et al.  Maternal Glucocorticoid Secretion Mediates Long-Term Effects of Prenatal Stress , 1996, The Journal of Neuroscience.

[13]  Shakti Sharma,et al.  Sex-specific effects of prenatal stress on hypothalamic-pituitary-adrenal responses to stress and brain glucocorticoid receptor density in adult rats. , 1995, Brain research. Developmental brain research.

[14]  D. Skuse Motherhood in Human and Nonhuman Primates: Biosocial Determinants , 1995 .

[15]  G. Sackett,et al.  Maternal Exposure to Stress during Pregnancy: Its Significance for Infant Behavior in Pigtail Macaques (Macaca nemestrina) , 1995 .

[16]  O. Pryds,et al.  PRENATAL STRESSORS OF HUMAN LIFE AFFECT FETAL BRAIN DEVELOPMENT , 1994, Developmental medicine and child neurology.

[17]  P. Wadhwa,et al.  The association between prenatal stress and infant birth weight and gestational age at birth: a prospective investigation. , 1993, American journal of obstetrics and gynecology.

[18]  J. Kagan,et al.  A 3-year follow-up of children with and without behavioral inhibition. , 1993, Journal of the American Academy of Child and Adolescent Psychiatry.

[19]  A. Clarke,et al.  Prenatal stress has long-term effects on behavioral responses to stress in juvenile rhesus monkeys. , 1993, Developmental psychobiology.

[20]  J. Kagan,et al.  Behavioral Inhibition in Childhood: A Risk Factor for Anxiety Disorders , 1993 .

[21]  D. Fergusson,et al.  Maternal age and cognitive and behavioural outcomes in middle childhood. , 1993, Paediatric and perinatal epidemiology.

[22]  B. McEwen,et al.  Prenatal stress selectively alters the reactivity of the hypothalamic-pituitary adrenal system in the female rat , 1992, Brain Research.

[23]  C. Victora,et al.  A randomized trial of psychosocial support during high-risk pregnancies , 1992 .

[24]  Mary L. Schneider,et al.  The effect of mild stress during pregnancy on birthweight and neuromotor maturation in rhesus monkey infants () , 1992 .

[25]  C. Coe,et al.  Endocrine activation mimics the adverse effects of prenatal stress on the neuromotor development of the infant primate. , 1992, Developmental psychobiology.

[26]  Gordon L. Flett,et al.  The Perceived Stress Scale: Factor structure and relation to depression symptoms in a psychiatric sample , 1992 .

[27]  P. Piazza,et al.  Increased locomotor response to novelty and propensity to intravenous amphetamine self-administration in adult offspring of stressed mothers , 1992, Brain Research.

[28]  Mary L. Schneider Delayed Object Permanence Development in Prenatally Stressed Rhesus Monkey Infants (Macaca Mulatta) , 1992 .

[29]  T. Field Infants of depressed mothers , 1992, Development and Psychopathology.

[30]  Stuart Oskamp,et al.  The social psychology of health , 1990 .

[31]  Van den Bergh,et al.  The influence of maternal emotions during pregnancy on fetal and neonatal behavior , 1990 .

[32]  M. Pagel,et al.  Psychosocial influences on new born outcomes: a controlled prospective study. , 1990, Social science & medicine.

[33]  J. Cohn,et al.  Specificity of infants' response to mothers' affective behavior. , 1989, Journal of the American Academy of Child and Adolescent Psychiatry.

[34]  J. Bates Concepts and measures of temperament. , 1989 .

[35]  J. Bates,et al.  Temperament in childhood. , 1989 .

[36]  Sheldon Cohen Perceived stress in a probability sample of the United States , 1988 .

[37]  J. Cox,et al.  Detection of Postnatal Depression , 1987, British Journal of Psychiatry.

[38]  Naeye Rl,et al.  Mental development of children whose mothers smoked during pregnancy. , 1984 .

[39]  T. Kamarck,et al.  A global measure of perceived stress. , 1983, Journal of health and social behavior.

[40]  M. Banks Validation of the General Health Questionnaire in a young community sample , 1983, Psychological Medicine.

[41]  S. Folkman,et al.  Relationship of daily hassles, uplifts, and major life events to health status , 1982 .

[42]  J. Bates,et al.  Measurement of infant difficultness. , 1979, Child development.

[43]  D. Goldberg The detection of psychiatric illness by questionnaire : a technique for the identification and assessment of non-psychotic psychiatric illness , 1972 .

[44]  J. Archer,et al.  Prenatal psychological stress and offspring behavior in rats and mice. , 1971, Developmental psychobiology.

[45]  A J Ferreira,et al.  EMOTIONAL FACTORS IN PRENATAL ENVIRONMENT A Review , 1965, The Journal of nervous and mental disease.