Bone Morphogenetic Protein-Modulator BMPER Regulates Endothelial Barrier Function

[1]  P. Knaus,et al.  BMP signaling in vascular biology and dysfunction. , 2016, Cytokine & growth factor reviews.

[2]  S. Vukicevic,et al.  VE-cadherin facilitates BMP-induced endothelial cell permeability and signaling , 2016, Journal of Cell Science.

[3]  C. Patterson,et al.  The role of BMPs in endothelial cell function and dysfunction , 2014, Trends in Endocrinology & Metabolism.

[4]  A. A. Abu El-Asrar,et al.  Bone morphogenetic protein 2: a potential new player in the pathogenesis of diabetic retinopathy. , 2014, Experimental eye research.

[5]  J. Gavard.  Endothelial permeability and VE-cadherin , 2013, Cell adhesion & migration.

[6]  E. Dejana,et al.  VE-cadherin and endothelial adherens junctions: active guardians of vascular integrity. , 2013, Developmental cell.

[7]  S. Grundmann,et al.  Inhibition of BMP activity protects epithelial barrier function in lung injury , 2013, Journal of Pathology.

[8]  E. Dejana,et al.  The role of VE-cadherin in vascular morphogenesis and permeability control. , 2013, Progress in molecular biology and translational science.

[9]  J. Schisler,et al.  Bmper Inhibits Endothelial Expression of Inflammatory Adhesion Molecules and Protects Against Atherosclerosis , 2012, Arteriosclerosis, thrombosis, and vascular biology.

[10]  P. ten Dijke,et al.  BMP signaling in vascular diseases , 2012, FEBS letters.

[11]  P. ten Dijke,et al.  TGFβ Signaling and Cardiovascular Diseases , 2012, International journal of biological sciences.

[12]  S. Grundmann,et al.  BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium. , 2011, Blood.

[13]  S. Nicholas,et al.  Activation of Vascular Bone Morphogenetic Protein Signaling in Diabetes Mellitus , 2011, Circulation research.

[14]  S. Yuan,et al.  Regulation of Endothelial Barrier Function , 2011 .

[15]  Limei Liu,et al.  Bone Morphogenic Protein-4 Impairs Endothelial Function through Oxidative Stress–dependent Cyclooxygenase-2 Upregulation Implications on Hypertension Methods and Results: Impaired Endothelium-dependent Relaxations, Exaggerated Endothelium-dependent Con- Tractions, and Reactive Oxygen Species (ros) P , 2022 .

[16]  C. Bode,et al.  BMPER Is Upregulated by Statins and Modulates Endothelial Inflammation by Intercellular Adhesion Molecule–1 , 2010, Arteriosclerosis, thrombosis, and vascular biology.

[17]  A. Malik,et al.  Regulation of endothelial permeability via paracellular and transcellular transport pathways. , 2010, Annual review of physiology.

[18]  C. Bode,et al.  Krüppel-like factor 15 regulates BMPER in endothelial cells. , 2010, Cardiovascular research.

[19]  R. Kalluri,et al.  Conversion of vascular endothelial cells into multipotent stem-like cells , 2010, Nature Medicine.

[20]  Z. Ungvari,et al.  Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression. , 2009, Antioxidants & redox signaling.

[21]  L. Attisano,et al.  A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling , 2009, The Journal of cell biology.

[22]  D. Vestweber,et al.  Cell adhesion dynamics at endothelial junctions: VE-cadherin as a major player. , 2009, Trends in cell biology.

[23]  C. Coffinier,et al.  Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation. , 2008, Developmental biology.

[24]  ChristophBode,et al.  BMPER Is an Endothelial Cell Regulator and Controls Bone Morphogenetic Protein-4–Dependent Angiogenesis , 2008 .

[25]  P. Carmeliet,et al.  The FGF system has a key role in regulating vascular integrity. , 2008, The Journal of clinical investigation.

[26]  H. Jo,et al.  Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells. , 2008, American journal of physiology. Heart and circulatory physiology.

[27]  A. Kotzsch,et al.  Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding. , 2008, Developmental cell.

[28]  J. Catravas,et al.  Heat shock protein 90 inhibitors attenuate LPS-induced endothelial hyperpermeability. , 2008, American journal of physiology. Lung cellular and molecular physiology.

[29]  A. Malik,et al.  Regulation of Endothelial Junctional Permeability , 2008, Annals of the New York Academy of Sciences.

[30]  B. Hogan,et al.  Endothelial Bmp4 is induced during arterial remodeling: effects on smooth muscle cell migration and proliferation. , 2008, The Journal of surgical research.

[31]  D. Vestweber,et al.  VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. , 2007, Arteriosclerosis, thrombosis, and vascular biology.

[32]  D. Giddens,et al.  Bone Morphogenic Protein Antagonists Are Coexpressed With Bone Morphogenic Protein 4 in Endothelial Cells Exposed to Unstable Flow In Vitro in Mouse Aortas and in Human Coronary Arteries: Role of Bone Morphogenic Protein Antagonists in Inflammation and Atherosclerosis , 2007, Circulation.

[33]  C. Bode,et al.  BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish. , 2007, Journal of molecular and cellular cardiology.

[34]  T. Rabelink,et al.  Endothelial function and dysfunction: testing and clinical relevance. , 2007, Circulation.

[35]  D. Harrison,et al.  Bone Morphogenic Protein-4 Induces Hypertension in Mice: Role of Noggin, Vascular NADPH Oxidases, and Impaired Vasorelaxation , 2006, Circulation.

[36]  Z. Ungvari,et al.  Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. , 2006, The American journal of pathology.

[37]  A. Malik,et al.  Signaling mechanisms regulating endothelial permeability. , 2006, Physiological reviews.

[38]  Z. Ungvari,et al.  Regulation of Bone Morphogenetic Protein-2 Expression in Endothelial Cells , 2005 .

[39]  Manu O. Platt,et al.  Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Induces Monocyte Adhesion by Stimulating Reactive Oxygen Species Production From a Nox1-Based NADPH Oxidase , 2004, Circulation research.

[40]  F. Conlon,et al.  BMPER, a Novel Endothelial Cell Precursor-Derived Protein, Antagonizes Bone Morphogenetic Protein Signaling and Endothelial Cell Differentiation , 2003, Molecular and Cellular Biology.

[41]  M. Goumans,et al.  Stimulation of Id1 Expression by Bone Morphogenetic Protein Is Sufficient and Necessary for Bone Morphogenetic Protein–Induced Activation of Endothelial Cells , 2002, Circulation.

[42]  K. Miyazono,et al.  Smad6 Is a Smad1/5-induced Smad Inhibitor , 2000, The Journal of Biological Chemistry.

[43]  M. Corada,et al.  Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[44]  K. Watson,et al.  Bone morphogenetic protein expression in human atherosclerotic lesions. , 1993, The Journal of clinical investigation.