Dietary supplementation with soy isoflavones or replacement with soy proteins prevents hepatic lipid droplet accumulation and alters expression of genes involved in lipid metabolism in rats

[1]  Jeremy E. Davis,et al.  Fat Accumulation in the Liver of Obese Rats is Alleviated by Soy Protein Isolate through β-catenin signaling , 2013, Obesity.

[2]  K. Petersen,et al.  Role of Patatin-Like Phospholipase Domain-Containing 3 on Lipid-Induced Hepatic Steatosis and Insulin Resistance in Rats , 2013, Hepatology.

[3]  J. Borén,et al.  Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro. , 2012, Journal of hepatology.

[4]  H. Katagiri,et al.  Hepatic peroxisome proliferator-activated receptor-γ-fat-specific protein 27 pathway contributes to obesity-related hypertension via afferent vagal signals. , 2012, European heart journal.

[5]  K. Kang,et al.  Isoflavones as a smart curer for non-alcoholic fatty liver disease and pathological adiposity via ChREBP and Wnt signaling. , 2012, Preventive medicine.

[6]  G. Fuchs,et al.  Dietary soy protein induces hepatic lipogenic enzyme gene expression while suppressing hepatosteatosis in obese female Zucker rats bearing DMBA-initiated mammary tumors , 2012, Genes & Nutrition.

[7]  S. Miura,et al.  Dietary β-conglycinin prevents fatty liver induced by a high-fat diet by a decrease in peroxisome proliferator-activated receptor γ2 protein. , 2012, The Journal of nutritional biochemistry.

[8]  E. Ferreira,et al.  β-conglycinin combined with fenofibrate or rosuvastatin have exerted distinct hypocholesterolemic effects in rats , 2012, Lipids in Health and Disease.

[9]  J. Suárez,et al.  Reduction of body weight, liver steatosis and expression of stearoyl‐CoA desaturase 1 by the isoflavone daidzein in diet‐induced obesity , 2011, British journal of pharmacology.

[10]  P. Fassini,et al.  Soybean glycinin improves HDL-C and suppresses the effects of rosuvastatin on hypercholesterolemic rats , 2011, Lipids in Health and Disease.

[11]  K. Kang,et al.  Daidzein supplementation prevents non-alcoholic fatty liver disease through alternation of hepatic gene expression profiles and adipocyte metabolism , 2011, International Journal of Obesity.

[12]  T. Konishi,et al.  Tofu (soybean curd) lowers serum lipid levels and modulates hepatic gene expression involved in lipogenesis primarily through its protein, not isoflavone, component in rats. , 2011, Journal of agricultural and food chemistry.

[13]  L. Uribe-Figueroa,et al.  White adipose tissue genome wide-expression profiling and adipocyte metabolic functions after soy protein consumption in rats. , 2011, The Journal of nutritional biochemistry.

[14]  K. Kang,et al.  The inhibitory effect of genistein on hepatic steatosis is linked to visceral adipocyte metabolism in mice with diet-induced non-alcoholic fatty liver disease. , 2010, The British journal of nutrition.

[15]  R. Prior,et al.  Soy protein diet alters expression of hepatic genes regulating fatty acid and thyroid hormone metabolism in the male rat. , 2010, The Journal of nutritional biochemistry.

[16]  F. Horio,et al.  β-Conglycinin Lowers Very-Low-Density Lipoprotein-Triglyceride Levels by Increasing Adiponectin and Insulin Sensitivity in Rats , 2010, Bioscience, biotechnology, and biochemistry.

[17]  P. Nallasamy,et al.  Genistein improves liver function and attenuates non‐alcoholic fatty liver disease in a rat model of insulin resistance , 2009, Journal of diabetes.

[18]  M. Fukuda,et al.  Effects of Lactobacillus Fermented Soymilk and Soy Yogurt on Hepatic Lipid Accumulation in Rats Fed a Cholesterol-Free Diet , 2009, Bioscience, biotechnology, and biochemistry.

[19]  T. Kawada,et al.  Changes in lipid metabolism by soy beta-conglycinin-derived peptides in HepG2 cells. , 2009, Journal of agricultural and food chemistry.

[20]  K. Shankar,et al.  Soy Protein Isolate Reduces Hepatosteatosis in Yellow Avy/a Mice Without Altering Coat Color Phenotype , 2008, Experimental biology and medicine.

[21]  Alexander Pertsemlidis,et al.  Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease , 2008, Nature Genetics.

[22]  Wendy S. Wright,et al.  Fat-specific Protein 27 Regulates Storage of Triacylglycerol* , 2008, Journal of Biological Chemistry.

[23]  F. Gonzalez,et al.  Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27. , 2008, Cell metabolism.

[24]  N. Torres,et al.  Soy protein ameliorates metabolic abnormalities in liver and adipose tissue of rats fed a high fat diet. , 2008, The Journal of nutrition.

[25]  A. Chawla,et al.  Fat-specific Protein 27, a Novel Lipid Droplet Protein That Enhances Triglyceride Storage* , 2007, Journal of Biological Chemistry.

[26]  M. Czech,et al.  RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27 , 2007, Acta physiologica.

[27]  N. Torres,et al.  The role of dietary protein on lipotoxicity. , 2007, Nutrition reviews.

[28]  Jeremy E. Davis,et al.  Soy Protein and Isoflavones Influence Adiposity and Development of Metabolic Syndrome in the Obese Male ZDF Rat , 2007, Annals of Nutrition and Metabolism.

[29]  Z. Younossi,et al.  Epidemiology and natural history of NAFLD and NASH. , 2007, Clinics in liver disease.

[30]  R. Berge,et al.  Dietary soya protein concentrate enriched with isoflavones reduced fatty liver, increased hepatic fatty acid oxidation and decreased the hepatic mRNA level of VLDL receptor in obese Zucker rats , 2006, British Journal of Nutrition.

[31]  N. Torres,et al.  Regulation of lipid metabolism by soy protein and its implication in diseases mediated by lipid disorders. , 2006, The Journal of nutritional biochemistry.

[32]  M. Bradbury.  Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis. , 2006, American journal of physiology. Gastrointestinal and liver physiology.

[33]  C. Aguilar-Salinas,et al.  Soy protein reduces hepatic lipotoxicity in hyperinsulinemic obese Zucker fa/fa rats Published, JLR Papers in Press, July 1, 2005. DOI 10.1194/jlr.M500067-JLR200 , 2005, Journal of Lipid Research.

[34]  Matej Oresic,et al.  The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform. , 2005, Diabetes.

[35]  Jonathan C. Cohen,et al.  Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity , 2004, Hepatology.

[36]  L. Granieri,et al.  Soy‐based formulas and phyto‐oestrogens: a safety profile , 2003, Acta paediatrica (Oslo, Norway : 1992). Supplement.

[37]  C. Aguilar-Salinas,et al.  A soy protein diet alters hepatic lipid metabolism gene expression and reduces serum lipids and renal fibrogenic cytokines in rats with chronic nephrotic syndrome. , 2002, The Journal of nutrition.

[38]  Lawrence A Leiter,et al.  Effects of high- and low-isoflavone soyfoods on blood lipids, oxidized LDL, homocysteine, and blood pressure in hyperlipidemic men and women. , 2002, The American journal of clinical nutrition.

[39]  J. Parks,et al.  Intact dietary soy protein, but not adding an isoflavone-rich soy extract to casein, improves plasma lipids in ovariectomized cynomolgus monkeys. , 1999, The Journal of nutrition.

[40]  B. Spiegelman,et al.  Regulation of PPAR gamma gene expression by nutrition and obesity in rodents. , 1996, The Journal of clinical investigation.

[41]  W. Forsythe,et al.  Soy protein, thyroid regulation and cholesterol metabolism. , 1995, The Journal of nutrition.

[42]  P. Murphy,et al.  Isoflavone content in commercial soybean foods , 1994 .

[43]  P. G. Reeves,et al.  AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. , 1993, The Journal of nutrition.

[44]  J. Folch,et al.  A simple method for the isolation and purification of total lipides from animal tissues. , 1957, The Journal of biological chemistry.

[45]  張維君.  Patatin-like phospholipase domain containing 3基因多型性與第二型糖尿病的巨量白蛋白尿之關聯性 , 2009 .

[46]  M. Anthony,et al.  The inhibitory effect of soy protein isolate on atherosclerosis in mice does not require the presence of LDL receptors or alteration of plasma lipoproteins. , 2002, The Journal of nutrition.

[47]  G. Burke,et al.  Soybean isoflavones improve cardiovascular risk factors without affecting the reproductive system of peripubertal rhesus monkeys. , 1996, The Journal of nutrition.

[48]  F. Schaffner,et al.  Nonalcoholic fatty liver disease. , 1986, Progress in liver diseases.