Perceptual learning in autism: over-specificity and possible remedies

Inflexible behavior is a core characteristic of autism spectrum disorder (ASD), but its underlying cause is unknown. Using a perceptual learning protocol, we observed initially efficient learning in ASD that was followed by anomalously poor learning when the location of the target was changed (over-specificity). Reducing stimulus repetition eliminated over-specificity. Our results indicate that inflexible behavior may be evident ubiquitously in ASD, even in sensory learning, but can be circumvented by specifically designed stimulation protocols.

[1]  M. Webster.  Adaptation and visual coding. , 2011, Journal of vision.

[2]  D. Sagi.  Perceptual learning in Vision Research , 2011, Vision Research.

[3]  J. Byrne.  Learning and memory : a comprehensive reference , 2008 .

[4]  Ning Qian,et al.  A Learning-Style Theory for Understanding Autistic Behaviors , 2011, Front. Hum. Neurosci..

[5]  B. Leventhal,et al.  The Autism Diagnostic Observation Schedule—Generic: A Standard Measure of Social and Communication Deficits Associated with the Spectrum of Autism , 2000, Journal of autism and developmental disorders.

[6]  D. Sagi,et al.  Effects of spatiotemporal consistencies on visual learning dynamics and transfer , 2015, Vision Research.

[7]  Mark W. Greenlee,et al.  Interactions among spatial frequency and orientation channels adapted concurrently , 1988, Vision Research.

[8]  R. Rosenfeld.  Nature , 2009, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[9]  H. J. S. Fernando,et al.  Grain sorting on sand ripples in heterogeneous sediments , 2008, J. Vis..

[10]  D. Sagi,et al.  Generalized Perceptual Learning in the Absence of Sensory Adaptation , 2012, Current Biology.

[11]  C. Sumiyoshi,et al.  Impaired ability to organize information in individuals with autism spectrum disorders and their siblings , 2011, Neuroscience Research.

[12]  S. Hochstein,et al.  Task difficulty and the specificity of perceptual learning , 1997, Nature.

[13]  Richard N Aslin,et al.  Enhanced visual statistical learning in adults with autism. , 2015, Neuropsychology.

[14]  Takeo Watanabe,et al.  Accounting for speed–accuracy tradeoff in perceptual learning , 2012, Vision Research.

[15]  S. Kaufman,et al.  Intact implicit learning in autism spectrum conditions , 2010, Quarterly journal of experimental psychology.

[16]  D Sagi,et al.  Where practice makes perfect in texture discrimination: evidence for primary visual cortex plasticity. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[17]  A. Couteur,et al.  Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders , 1994, Journal of autism and developmental disorders.

[18]  Roger Ratcliff,et al.  Dissociable Perceptual-learning Mechanisms Revealed by Diffusion-model Analysis , 2022 .