Preventive Inhalation of Hypertonic Saline in Infants with Cystic Fibrosis (PRESIS). A Randomized, Double-Blind, Controlled Study.
暂无分享,去创建一个
O. Sommerburg | M. Wielpütz | C. Koerner-Rettberg | J. Hüsing | M. Kopp | M. Mall | A. Dittrich | A. Schlegtendal | C. Dopfer | M. Stahl | L. Nährlich | S. Graeber | Isabell Ricklefs | S. Barth | Gesa Diekmann | I. Ricklefs
[1] M. Gentzsch,et al. Ion Channel Modulators in Cystic Fibrosis , 2018, Chest.
[2] H. Kauczor,et al. Multicentre standardisation of chest MRI as radiation-free outcome measure of lung disease in young children with cystic fibrosis. , 2018, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.
[3] R. Boucher,et al. The in vitro effect of nebulised hypertonic saline on human bronchial epithelium , 2018, European Respiratory Journal.
[4] H. Kauczor,et al. Non-contrast enhanced magnetic resonance imaging detects mosaic signal intensity in early cystic fibrosis lung disease. , 2018, European journal of radiology.
[5] U. Frey,et al. Elevated lung clearance index in infants with cystic fibrosis shortly after birth , 2017, European Respiratory Journal.
[6] C. Meyer,et al. Hyperpolarized helium-3 magnetic resonance lung imaging of non-sedated infants and young children: a proof-of-concept study. , 2017, Clinical imaging.
[7] M. Kopp,et al. Three-center feasibility of lung clearance index in infants and preschool children with cystic fibrosis and other lung diseases. , 2017, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.
[8] S. Stanojevic,et al. Efficacy and safety of lumacaftor and ivacaftor in patients aged 6-11 years with cystic fibrosis homozygous for F508del-CFTR: a randomised, placebo-controlled phase 3 trial. , 2017, The Lancet. Respiratory medicine.
[9] S. Stanojevic,et al. Progression of Lung Disease in Preschool Patients with Cystic Fibrosis , 2017, American journal of respiratory and critical care medicine.
[10] M. Wielpütz,et al. MRI accelerating progress in functional assessment of cystic fibrosis lung disease. , 2017, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.
[11] R. Szczesniak,et al. Ultrashort Echo-Time Magnetic Resonance Imaging Is a Sensitive Method for the Evaluation of Early Cystic Fibrosis Lung Disease. , 2016, Annals of the American Thoracic Society.
[12] H. Kauczor,et al. Early detection and sensitive monitoring of CF lung disease: Prospects of improved and safer imaging , 2016, Pediatric pulmonology.
[13] Hans-Ulrich Kauczor,et al. Comparison of Lung Clearance Index and Magnetic Resonance Imaging for Assessment of Lung Disease in Children with Cystic Fibrosis , 2016, American journal of respiratory and critical care medicine.
[14] C. Castellani,et al. Newborn screening for cystic fibrosis. , 2016, The Lancet. Respiratory medicine.
[15] M Puderbach,et al. Imaging of Cystic Fibrosis Lung Disease and Clinical Interpretation , 2016, RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren.
[16] S. Stick,et al. Lung Clearance Index and Structural Lung Disease on Computed Tomography in Early Cystic Fibrosis. , 2015, American journal of respiratory and critical care medicine.
[17] I. Korten,et al. False normal Lung Clearance Index in infants with cystic fibrosis due to software algorithms , 2015, Pediatric pulmonology.
[18] S. Stick,et al. Progressive ventilation inhomogeneity in infants with cystic fibrosis after pulmonary infection , 2015, European Respiratory Journal.
[19] P. Sly,et al. Early respiratory infection is associated with reduced spirometry in children with cystic fibrosis. , 2014, American journal of respiratory and critical care medicine.
[20] M. Mall,et al. Early cystic fibrosis lung disease: Role of airway surface dehydration and lessons from preventive rehydration therapies in mice. , 2014, The international journal of biochemistry & cell biology.
[21] D. Hartl,et al. CFTR: cystic fibrosis and beyond , 2014, European Respiratory Journal.
[22] H. Kauczor,et al. Magnetic resonance imaging detects changes in structure and perfusion, and response to therapy in early cystic fibrosis lung disease. , 2014, American journal of respiratory and critical care medicine.
[23] O. Sommerburg,et al. Multiple Breath Washout Is Feasible in the Clinical Setting and Detects Abnormal Lung Function in Infants and Young Children with Cystic Fibrosis , 2014, Respiration.
[24] P. Lee,et al. Assessment of clinical response to ivacaftor with lung clearance index in cystic fibrosis patients with a G551D-CFTR mutation and preserved spirometry: a randomised controlled trial. , 2013, The Lancet. Respiratory medicine.
[25] R. Boucher,et al. Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease. , 2013, American journal of respiratory cell and molecular biology.
[26] S. Stanojevic,et al. Lung clearance index as an outcome measure for clinical trials in young children with cystic fibrosis. A pilot study using inhaled hypertonic saline. , 2013, American journal of respiratory and critical care medicine.
[27] Peter D Sly,et al. Risk factors for bronchiectasis in children with cystic fibrosis. , 2013, The New England journal of medicine.
[28] F. Ratjen,et al. Early lung disease in cystic fibrosis. , 2013, The Lancet. Respiratory medicine.
[29] M. Rosenfeld,et al. Early intervention studies in infants and preschool children with cystic fibrosis: are we ready? , 2013, European Respiratory Journal.
[30] Janet Stocks,et al. Consensus statement for inert gas washout measurement using multiple- and single- breath tests , 2013, European Respiratory Journal.
[31] A. Numa,et al. Early cystic fibrosis lung disease detected by bronchoalveolar lavage and lung clearance index. , 2012, American journal of respiratory and critical care medicine.
[32] S. Stanojevic,et al. Age and height dependence of lung clearance index and functional residual capacity , 2012, European Respiratory Journal.
[33] K. Rabe,et al. Das Deutsche Zentrum für Lungenforschung – Translationale Forschung für Prävention, Diagnose und Therapie von Atemwegserkrankungen , 2012, Pneumologie.
[34] A. Wade,et al. Lung function is abnormal in 3-month-old infants with cystic fibrosis diagnosed by newborn screening , 2012, Thorax.
[35] R. Kronmal,et al. Inhaled hypertonic saline in infants and children younger than 6 years with cystic fibrosis: the ISIS randomized controlled trial. , 2012, JAMA.
[36] Annette Kopp-Schneider,et al. Morphologic and functional scoring of cystic fibrosis lung disease using MRI. , 2012, European journal of radiology.
[37] M. Welsh,et al. Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report. , 2012, American journal of respiratory and critical care medicine.
[38] P. Sly,et al. Air Trapping on Chest CT Is Associated with Worse Ventilation Distribution in Infants with Cystic Fibrosis Diagnosed following Newborn Screening , 2011, PloS one.
[39] M. Rosenfeld,et al. Inhaled hypertonic saline in infants and toddlers with cystic fibrosis: short‐term tolerability, adherence, and safety , 2011, Pediatric pulmonology.
[40] T. Riedel,et al. Normative data for lung function and exhaled nitric oxide in unsedated healthy infants , 2010, European Respiratory Journal.
[41] F. Ratjen,et al. Hypertonic saline improves the LCI in paediatric patients with CF with normal lung function , 2010, Thorax.
[42] P. Sly,et al. Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening. , 2009, American journal of respiratory and critical care medicine.
[43] M. Goldman,et al. Inert Gas Washout: Theoretical Background and Clinical Utility in Respiratory Disease , 2009, Respiration.
[44] Margaret Rosenfeld,et al. Early anti-pseudomonal acquisition in young patients with cystic fibrosis: rationale and design of the EPIC clinical trial and observational study'. , 2009, Contemporary clinical trials.
[45] R. Boucher,et al. Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in betaENaC-overexpressing mice. , 2008, American journal of respiratory and critical care medicine.
[46] S. Donaldson,et al. Safety and tolerability of inhaled hypertonic saline in young children with cystic fibrosis , 2008, Pediatric pulmonology.
[47] D. Baldwin,et al. Optimized temperature and deadspace correction improve analysis of multiple breath washout measurements by ultrasonic flowmeter in infants , 2007, Pediatric pulmonology.
[48] F. Ratjen,et al. Pilot study of safety and tolerability of inhaled hypertonic saline in infants with cystic fibrosis , 2007, Pediatric pulmonology.
[49] A. Wade,et al. Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests , 2007, Thorax.
[50] R. Boucher. Airway surface dehydration in cystic fibrosis: pathogenesis and therapy. , 2007, Annual review of medicine.
[51] Janet Stocks,et al. Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis. , 2005, American journal of respiratory and critical care medicine.
[52] J. Stocks,et al. Multiple breath inert gas washout as a measure of ventilation distribution in children with cystic fibrosis , 2004, Thorax.
[53] M. Van Winckel,et al. Percutaneous endoscopic gastrostomy in cystic fibrosis: patient acceptance and effect of overnight tube feeding on nutritional status. , 2004, Acta gastro-enterologica Belgica.
[54] P. Gustafsson,et al. Evaluation of ventilation maldistribution as an early indicator of lung disease in children with cystic fibrosis , 2003, European Respiratory Journal.
[55] J. Wit,et al. Catch-Up Growth and Endocrine Changes in Childhood Celiac Disease , 2002, Hormone Research in Paediatrics.
[56] J. Müller,et al. Perzentile für den Body-mass-Index für das Kindes- und Jugendalter unter Heranziehung verschiedener deutscher Stichproben , 2001, Monatsschrift Kinderheilkunde.
[57] M. Hofbeck,et al. Percutaneous endoscopic gastrostomy in children and adolescents. , 1997, Journal of pediatric gastroenterology and nutrition.
[58] H. Fuchs,et al. Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group. , 1994, The New England journal of medicine.
[59] R. Kauffman,et al. American Academy of Pediatrics Committee on Drugs and Committee on Environmental Health: Use of chloral hydrate for sedation in children. , 1993, Pediatrics.
[60] Zusammenfassung,et al. Longitudinale Körperentwicklung gesunder Kinder von 0 bis 18 Jahren , 1992 .
[61] L. Rees,et al. Chronic renal failure and growth. , 1989, Archives of disease in childhood.
[62] A. Prader,et al. Dedicated to Dr. Guido Fanconi on the occasion of his 80th birthday Catch-up Growth in Malnutrition, Studied in Celiac Disease After Institution of Gluten-free Diet , 1972, Pediatric Research.
[63] J. Tanner,et al. Catch-up growth following illness or starvation. An example of developmental canalization in man. , 1963, The Journal of pediatrics.