Long-term outcome of ventral buccal mucosa onlay graft urethroplasty for urethral stricture repair.

OBJECTIVES To evaluate our patients who were treated with ventral buccal mucosa onlay grafts for open urethral stricture repair with a follow-up exceeding 5 years. Buccal mucosa onlay is widely used for urethral reconstruction; however, the long-term outcome of these patients remains unclear. METHODS During the past 10 years, 67 patients underwent ventral buccal mucosa onlay graft surgery for urethral stricture repair. Of these, 32 were followed up for longer than 5 years (mean 6.9 years) for the occurrence and timing of any postoperative complications. All patients had undergone prior internal urethrotomy (mean 2.9 procedures), and the average length of the stricture was 4.3 cm (range 3 to 17). RESULTS The overall complication rate was 25% (8 of 32). We observed one fistula, one graft infection/necrosis, two lower lip scars with transient impairment of lip motility, and four recurrent strictures (at the proximal anastomosis), all of which were treated successfully with internal urethrotomy. All but one recurrent stricture occurred during the first 12 postoperative months. CONCLUSIONS Ventral buccal mucosa onlay grafting for urethral stricture repair provides stable long-term results with complications occurring primarily during the first 12 postoperative months.

[1]  D. Falchetti,et al.  Autologous buccal mucosa graft for hypospadias repair: an initial report. , 1992, The Journal of urology.

[2]  A. Mundy,et al.  Substitution urethroplasty with buccal mucosal-free grafts. , 2001, The Journal of urology.

[3]  E. Gerharz,et al.  Ventral onlay urethroplasty using buccal mucosa for complex stricture repair. , 2003, Urology.

[4]  R. Hohenfellner,et al.  The buccal mucosal graft for urethral reconstruction: a preliminary report. , 1992, The Journal of urology.

[5]  A. Noweir,et al.  The use of buccal mucosa patch graft in the management of anterior urethral strictures. , 1993, The Journal of urology.

[6]  J. Fitzpatrick,et al.  The histology and immunohistochemistry of free buccal mucosa and full‐skin grafts after exposure to urine , 1999, BJU international.

[7]  A. Morey,et al.  When and how to use buccal mucosal grafts in adult bulbar urethroplasty. , 1996, Urology.

[8]  M. Rizzo,et al.  Long-term results of anterior and posterior urethroplasty with actuarial evaluation of the success rates. , 1997, The Journal of urology.

[9]  C. Kane,et al.  Multi-institutional experience with buccal mucosa onlay urethroplasty for bulbar urethral reconstruction. , 2002, The Journal of urology.

[10]  A. Morey,et al.  Single stage reconstruction of complex anterior urethral strictures: combined tissue transfer techniques. , 1997, The Journal of urology.

[11]  A. Mundy The long-term results of skin inlay urethroplasty. , 1995, British journal of urology.

[12]  T. Higgins,et al.  A one‐stage operation for hypospadias , 1941 .

[13]  V. Pansadoro,et al.  BUCCAL MUCOSA URETHROPLASTY FOR THE TREATMENT OF BULBAR URETHRAL STRICTURES , 1999 .

[14]  H. Wessells,et al.  Current controversies in anterior urethral stricture repair: free-graft versus pedicled skin-flap reconstruction , 1998, World Journal of Urology.

[15]  A. Mundy,et al.  The Barbagli procedure gives the best results for patch urethroplasty of the bulbar urethra , 2001, BJU international.

[16]  M. Rizzo,et al.  Dorsal onlay graft urethroplasty using penile skin or buccal mucosa in adult bulbourethral strictures. , 1998, The Journal of urology.