Triplex molecular beacons for sensitive recognition of melamine based on abasic-site-containing DNA and fluorescent silver nanoclusters.

A melamine aptamer derived from an abasic-site-containing triplex molecular beacon (tMB) was designed and developed for sensitive recognition of melamine by integrating tMBs and fluorescent silver nanoclusters (Ag NCs).

[1]  Nicholas O Fischer,et al.  Aptasensors for biosecurity applications. , 2007, Current opinion in chemical biology.

[2]  W. Marsden.  I and J , 2012 .

[3]  J. Szostak,et al.  In vitro selection of RNA molecules that bind specific ligands , 1990, Nature.

[4]  Zhiai Xu,et al.  Label-free aptamer-based sensor using abasic site-containing DNA and a nucleobase-specific fluorescent ligand. , 2009, Chemical communications.

[5]  Sanjay Tyagi,et al.  Molecular Beacons: Probes that Fluoresce upon Hybridization , 1996, Nature Biotechnology.

[6]  Hsin-Chih Yeh,et al.  A fluorescence light-up Ag nanocluster probe that discriminates single-nucleotide variants by emission color. , 2012, Journal of the American Chemical Society.

[7]  Norio Teramae,et al.  2-Aminopurine-modified abasic-site-containing duplex DNA for highly selective detection of theophylline. , 2009, Journal of the American Chemical Society.

[8]  Tao Yang,et al.  Recent Progresses in Nanobiosensing for Food Safety Analysis , 2016, Sensors.

[9]  Chad A Mirkin,et al.  A gold nanoparticle based approach for screening triplex DNA binders. , 2006, Journal of the American Chemical Society.

[10]  Keitaro Yoshimoto,et al.  Abasic-site-containing oligodeoxynucleotides as aptamers for riboflavin. , 2006, Angewandte Chemie.

[11]  Ioanis Katakis,et al.  Aptamers: molecular tools for analytical applications , 2008, Analytical and bioanalytical chemistry.

[12]  N. Teramae,et al.  Strong and selective binding of amiloride to thymine base opposite AP sites in DNA duplexes: simultaneous binding to DNA phosphate backbone. , 2006, Chemical communications.

[13]  Xindong Wang,et al.  Detection of cancer cells using triplex DNA molecular beacons based on expression of enhanced green fluorescent protein (eGFP). , 2014, Chemical communications.

[14]  L. Gold,et al.  Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. , 1990, Science.

[15]  Keitaro Yoshimoto,et al.  Use of abasic site-containing DNA strands for nucleobase recognition in water. , 2003, Journal of the American Chemical Society.

[16]  Shaojun Dong,et al.  A new approach to light up DNA/Ag nanocluster-based beacons for bioanalysis , 2013 .

[17]  Itamar Willner,et al.  Electronic aptamer-based sensors. , 2007, Angewandte Chemie.

[18]  N. Teramae,et al.  Alloxazine as a ligand for selective binding to adenine opposite AP sites in DNA duplexes and analysis of single-nucleotide polymorphisms. , 2008, Organic & biomolecular chemistry.

[19]  Lehui Lu,et al.  Hydrogen-bonding recognition-induced color change of gold nanoparticles for visual detection of melamine in raw milk and infant formula. , 2009, Journal of the American Chemical Society.

[20]  Zhiai Xu,et al.  Signal-off and signal-on design for a label-free aptasensor based on target-induced self-assembly and abasic-site-binding ligands. , 2009, Chemistry.

[21]  Yi Lu,et al.  Label-free catalytic and molecular beacon containing an abasic site for sensitive fluorescent detection of small inorganic and organic molecules. , 2012, Analytical chemistry.

[22]  Oliver Seitz,et al.  Triplex molecular beacons as modular probes for DNA detection. , 2007, Angewandte Chemie.

[23]  Michael Famulok,et al.  Input-Dependent Induction of Oligonucleotide Structural Motifs for Performing Molecular Logic , 2012, Journal of the American Chemical Society.

[24]  C. Mao,et al.  Reporting transient molecular events by DNA strand displacement. , 2014, Chemical communications.

[25]  Zhiqin Yuan,et al.  Fluorescent silver nanoclusters stabilized by DNA scaffolds. , 2014, Chemical communications.

[26]  N. Teramae,et al.  6,7-Dimethyllumazine as a potential ligand for selective recognition of adenine opposite an abasic site in DNA duplexes. , 2008, Chemical communications.

[27]  B. Ye,et al.  A label-free fluorescent molecular beacon based on DNA-templated silver nanoclusters for detection of adenosine and adenosine deaminase. , 2012, Chemical communications.

[28]  Chunhai Fan,et al.  Rational design of pH-controlled DNA strand displacement. , 2014, Journal of the American Chemical Society.

[29]  Jason J. Han,et al.  A DNA--silver nanocluster probe that fluoresces upon hybridization. , 2010, Nano letters.

[30]  Keitaro Yoshimoto,et al.  Fluorescence detection of guanine-adenine transition by a hydrogen bond forming small compound. , 2003, Chemical communications.