论文信息 - Irreversible inhibitors of serine, cysteine, and threonine proteases.

Irreversible inhibitors of serine, cysteine, and threonine proteases.

F. Vinyl Sulfones and Other Michael Acceptors 4683 G. Azodicarboxamides 4695 IV. Acylating Agents 4695 A. Aza-peptides 4695 B. Carbamates 4699 C. Peptidyl Acyl Hydroxamates 4700 D. â-Lactams and Related Inhibitors 4704 E. Heterocyclic Inhibitors 4714 1. Isocoumarins 4715 2. Benzoxazinones 4722 3. Saccharins 4725 4. Miscellaneous Heterocyclic Inhibitors 4728 V. Phosphonylation Agents 4728 A. Peptide Phosphonates 4728 B. Phosphonyl Fluorides 4734 VI. Sulfonylating Agents 4735 A. Sulfonyl Fluorides 4735 VII. Miscellaneous Inhibitors 4736 VIII. Summary and Perspectives 4737 IX. Acknowledgments 4740 X. Note Added in Proof 4740 XI. References 4740

[1] A. Barrett. Proteolytic enzymes : serine and cysteine peptidases , 1994 .

[2] G. Kortüm,et al. Disssociation constants of organic acids in aqueous solution , 1960 .

[3] R. Silverman. Mechanism-based enzyme inactivation : chemistry and enzymology , 1988 .

[4] L. Paoloni. Dissociation constants of organic acids in aqueous solution : G. Kortüm, W. Vogel and K. Andrussow, Butterworths, London, 1961, xxii + 347 pages, £ 2.108 , 1962 .