Verification of the Respiratory Parameters Derived from Impedance Pneumography during Normal and Deep Breathing in Three Body Postures

We designed a small, battery-powered impedance pneumograph intended for holter monitoring of respiratory activity. Volume-related signal from impedance pneumo-graphy (IP) and airflow signal from reference method, pneumotachometry (PNT), were registered. First derivate of IP with PNT and IP with integral of PNT signals were compared in order to calculate slope values of linear regression. The effect of respiratory rate, depths of breathing, body posture, sex and body mass index (BMI) on slope values and coefficients of determination (R2) was determined. The measurements were conducted on a group of young volunteers without any respiratory diseases. An electrode configuration known for its good linearity between impedance and volume signals was chosen. Average R2 between IP signal and integral of PNT signal was 98.05%, and between first derivative of IP signal and PNT signal – 95.75%. It was demonstrated that the slope values were individually different and affected mostly by body posture.

[1]  Jari Hyttinen,et al.  Novel electrode configuration for highly linear impedance pneumography , 2013, Biomedizinische Technik. Biomedical engineering.

[2]  Ville-Pekka Seppä,et al.  Tidal breathing flow-volume curves with impedance pneumography during expiratory loading , 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[3]  J T Kuikka,et al.  Bioimpedance-based measurement method for simultaneous acquisition of respiratory and cardiac gating signals , 2012, Physiological measurement.

[4]  M. Mäkelä,et al.  Tidal breathing flow measurement in awake young children by using impedance pneumography. , 2013, Journal of applied physiology.

[5]  Jari Hyttinen,et al.  Assessment of Pulmonary Flow Using Impedance Pneumography , 2010, IEEE Transactions on Biomedical Engineering.

[6]  Akihito Umezu,et al.  Modified thoracic impedance plethysmography to monitor sleep apnea syndromes. , 2005, Sleep medicine.

[7]  J. Houtveen,et al.  Validation of the thoracic impedance derived respiratory signal using multilevel analysis. , 2006, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[8]  D. Altman,et al.  STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT , 1986, The Lancet.

[9]  L.E. Baker.  Applications of the impedance technique to the respiratory system , 1989, IEEE Engineering in Medicine and Biology Magazine.

[10]  J. Cacioppo,et al.  Impedance pneumography: noise as signal in impedance cardiography. , 1999, Psychophysiology.

[11]  J M Bland,et al.  Statistical methods for assessing agreement between two methods of clinical measurement , 1986 .

[12]  A. Savitzky,et al.  Smoothing and Differentiation of Data by Simplified Least Squares Procedures. , 1964 .

[13]  Marcel Młyńczak,et al.  Design and construction of the artificial patient module for testing bioimpedance measuring devices , 2013, Other Conferences.

[14]  D. Altman,et al.  Measuring agreement in method comparison studies , 1999, Statistical methods in medical research.

[15]  J. P. Zock.  Linearity and frequency response of fleisch type pneumotachometers , 1981, Pflügers Archiv.

[16]  S P Stackhouse,et al.  Thoracic impedance gradient with respect to breathing. , 1970, IEEE transactions on bio-medical engineering.

[17]  G. Willemsen,et al.  Ambulatory measurement of respiratory sinus arrhythmia and respiration rate , 1995, Biological Psychology.

[18]  N. Chavannes,et al.  Validity of spirometric testing in a general practice population of patients with chronic obstructive pulmonary disease (COPD) , 2003, Thorax.

[19]  L H Hamilton,et al.  Factors affecting transthoracic impedance signals used to measure breathing. , 1967, Journal of applied physiology.

[20]  Jari Hyttinen.  Signal waveform agreement between spirometer and impedance pneumography of six chest band electrode configurations , 2009 .