The thyrotrophic role of human chorionic gonadotrophin (hCG) in the early stages of twin (versus single) pregnancies

Human chorionic gonadotrophin (hCG) is known to possess thyroid‐stimulating activity. The aim of the present study was to assess the role of hCG in stimulating the maternal thyroid gland in the early stages of normal gestation.

[1]  J. Hershman,et al.  Thyrotropic action of human chorionic gonadotropin. , 1995, Thyroid : official journal of the American Thyroid Association.

[2]  N. Amino,et al.  Pathogenic role of asialo human chorionic gonadotropin in gestational thyrotoxicosis. , 1995, The Journal of clinical endocrinology and metabolism.

[3]  L. Nelson,et al.  A potential novel mechanism for precocious puberty in juvenile hypothyroidism. , 1995, The Journal of clinical endocrinology and metabolism.

[4]  L. Cole,et al.  Increased concentration of the free β‐subunit of human chorionic gonadotropin in hyperemesis gravidarum , 1994, Acta obstetricia et gynecologica Scandinavica.

[5]  K. Nicolaides,et al.  Maternal plasma levels of human chorionic gonadotrophin, oestradiol and progesterone in multifetal pregnancies before and after fetal reduction. , 1994, The Journal of endocrinology.

[6]  J. Hershman,et al.  Thyrotropic activity of basic isoelectric forms of human chorionic gonadotropin extracted from hydatidiform mole tissues. , 1994, The Journal of clinical endocrinology and metabolism.

[7]  J. Kaufman,et al.  Total amounts of circulating human chorionic gonadotrophin alpha and beta subunits can be assessed throughout human pregnancy using immunoradiometric assays calibrated with the unaltered and thermally dissociated heterodimer. , 1994, The Journal of endocrinology.

[8]  D. Glinoer,et al.  Serum levels of intact human chorionic gonadotropin (HCG) and its free a and β subunits, in relation to maternal thyroid stimulation during normal pregnancy , 1993, Journal of endocrinological investigation.

[9]  D. Yarmush,et al.  The application of chemical studies of human chorionic gonadotropin to visualize its three-dimensional structure. , 1993, Endocrine reviews.

[10]  M. Ascoli,et al.  The lutropin/choriogonadotropin receptor ... 4 years later. , 1993, Endocrine reviews.

[11]  N. Amino,et al.  Gestational thyrotoxicosis and hyperemesis gravidarum: possible role of hCG with higher stimulating activity , 1993, Clinical endocrinology.

[12]  J. Jameson,et al.  Regulation of chorionic gonadotropin gene expression. , 1993, Endocrine reviews.

[13]  J. Hershman,et al.  The role of chorionic gonadotropin in transient hyperthyroidism of hyperemesis gravidarum. , 1992, The Journal of clinical endocrinology and metabolism.

[14]  J. Parma,et al.  The thyrotropin receptor and the regulation of thyrocyte function and growth. , 1992, Endocrine reviews.

[15]  R. Ekins,et al.  Pregnancy-induced changes in thyroid function: role of human chorionic gonadotropin as putative regulator of maternal thyroid. , 1991, The Journal of clinical endocrinology and metabolism.

[16]  R. Kennedy,et al.  The role of hCG in regulation of the thyroid gland in normal and abnormal pregnancy. , 1991, Obstetrics and gynecology.

[17]  R. Rawlins,et al.  Human chorionic gonadotropin rise in normal and vanishing twin pregnancies. , 1991, Fertility and sterility.

[18]  D. Glinoer,et al.  Regulation of maternal thyroid during pregnancy. , 1990, The Journal of clinical endocrinology and metabolism.

[19]  J. Magner,et al.  Thyroid-stimulating hormone: biosynthesis, cell biology, and bioactivity. , 1990, Endocrine reviews.

[20]  M. Ascoli,et al.  On the structure of the luteinizing hormone/chorionic gonadotropin receptor. , 1989, Endocrine reviews.

[21]  R. Hoermann,et al.  Thyrotropic activity of acidic isoelectric variants of human chorionic gonadotropin from trophoblastic tumors. , 1986, Endocrinology.

[22]  G. Braunstein,et al.  Comparison of serum pituitary thyrotropin and chorionic gonadotropin concentrations throughout pregnancy. , 1976, The Journal of clinical endocrinology and metabolism.

[23]  J. Hershman,et al.  The thyrotropin in hydatidiform moles is human chorionic gonadotropin. , 1975, The Journal of clinical endocrinology and metabolism.

[24]  J. Hershman.  Hyperthyroidism induced by trophoblastic thyrotropin. , 1972, Mayo Clinic proceedings.

[25]  J. Hershman,et al.  Hydatidiform mole--a cause of clinical hyperthyroidism. Report of two cases with evidence that the molar tissue secreted a thyroid stimulator. , 1971, The New England journal of medicine.