SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19
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G. Berry | T. Montine | H. Shill | A. Atri | C. Adler | D. Dickson | E. Reiman | R. Caselli | C. Belden | J. Zehnder | M. Huentelman | C. Bime | S. Mehta | Haiyu Zhang | S. Boyd | G. Serrano | I. Piras | B. Pinsky | L. Sue | B. Woodruff | M. Desforges | P. Talbot | M. DeTure | Erika Driver‐Dunckley | J. Mizgerd | M. Sahoo | A. Intorcia | Michael J. Glass | Jessica E. Walker | R. Arce | C. Nelson | Danielle Goldfarb | D. Shprecher | J. Oliver | Steven Z. Rapscak | D. Solis | K. Röltgen | Thomas G. Beach | K. E. Suszczewicz | Cécilia Tremblay | Chadwick F Haarer | Thomas Ruhlen | Maria Torres | Steve Nguyen | Dasan Schmitt | Joseph L Peters | Ellie Alevritis | Daisy Vargas | C. M. Nelson | Javon Oliver | Aryck Russell | Claryssa I Borja | Madison P Cline | S. J. Hemmingsen | Sanaria Qiji | H. M. Hobgood | T. Beach | D. Vargas | C. Tremblay | C. I. Borja | M. P. Cline | S. Qiji
[1] C. Yasuda,et al. Morphological, cellular, and molecular basis of brain infection in COVID-19 patients , 2022, Proceedings of the National Academy of Sciences of the United States of America.
[2] H. Sung,et al. Prevalence of a Single-Nucleotide Variant of SARS-CoV-2 in Korea and Its Impact on the Diagnostic Sensitivity of the Xpert Xpress SARS-CoV-2 Assay , 2022, Annals of laboratory medicine.
[3] Thomas E. Nichols,et al. SARS-CoV-2 is associated with changes in brain structure in UK Biobank , 2022, Nature.
[4] R. Carlier,et al. Transient modifications of the olfactory bulb on MR follow-up of COVID-19 patients with related olfactory dysfunction , 2022, Journal of Neuroradiology.
[5] Sang Woo Park,et al. Direct and indirect mortality impacts of the COVID-19 pandemic in the US, March 2020-April 2021 , 2022, medRxiv.
[6] Mark M. Davis,et al. Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination , 2022, Cell.
[7] G. Serrano,et al. Deafferentation of Olfactory Bulb in Subjects Dying with COVID-19 , 2021, medRxiv.
[8] S. Pittaluga,et al. SARS-CoV-2 infection and persistence throughout the human body and brain , 2021 .
[9] T. Beach,et al. White Matter Beta-Amyloid Precursor Protein Immunoreactivity in Autopsied Subjects With and Without COVID-19 , 2021, medRxiv.
[10] R. Hotchkiss,et al. Overlapping but Disparate Inflammatory and Immunosuppressive Responses to SARS-CoV-2 and Bacterial Sepsis: An Immunological Time Course Analysis , 2021, Frontiers in Immunology.
[11] K. Kaila,et al. APOE ε4 associates with increased risk of severe COVID-19, cerebral microhaemorrhages and post-COVID mental fatigue: a Finnish biobank, autopsy and clinical study , 2021, Acta neuropathologica communications.
[12] C. Fuller,et al. Lethal Pediatric Cerebral Vasculitis Triggered by Severe Acute Respiratory Syndrome Coronavirus 2 , 2021, Pediatric Neurology.
[13] H. Zhou,et al. Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb , 2021, Cell.
[14] M. Boldrini,et al. COVID-19 induces neuroinflammation and loss of hippocampal neurogenesis , 2021, Research square.
[15] K. Fukunaga,et al. Memantine improves cognitive deficits via KATP channel inhibition in olfactory bulbectomized mice , 2021, Molecular and Cellular Neuroscience.
[16] A. Baykan,et al. Quantitative Analysis of the Olfactory System in COVID-19: An MR Imaging Study , 2021, American Journal of Neuroradiology.
[17] D. Dickson,et al. Olfactory Bulb and Amygdala Gene Expression Changes in Subjects Dying with COVID-19 , 2021, medRxiv.
[18] R. Nardacci,et al. Neuropathology and Inflammatory Cell Characterization in 10 Autoptic COVID-19 Brains , 2021, Cells.
[19] A. Bruni-Cardoso,et al. The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling , 2021, Journal of Biological Chemistry.
[20] A. Pisani,et al. Neuropathological findings from COVID‐19 patients with neurological symptoms argue against a direct brain invasion of SARS‐CoV‐2: A critical systematic review , 2021, European journal of neurology.
[21] L. Enquist,et al. Post-viral effects of COVID-19 in the olfactory system and their implications , 2021, The Lancet Neurology.
[22] M. Biasin,et al. Olfactory bulb SARS‐CoV‐2 infection is not paralleled by the presence of virus in other central nervous system areas , 2021, Neuropathology and applied neurobiology.
[23] M. Fowkes,et al. Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19 , 2021, Genome medicine.
[24] Yongqiang Deng,et al. SARS-CoV-2 infection in the mouse olfactory system , 2021, Cell discovery.
[25] D. Melzer,et al. APOE e4 Genotypes Increase Risk of Delirium During COVID-19-Related Hospitalizations: Evidence From a Large UK Cohort , 2021, The journals of gerontology. Series A, Biological sciences and medical sciences.
[26] I. Cobos,et al. Dysregulation of brain and choroid plexus cell types in severe COVID-19 , 2021, Nature.
[27] O. Pansarasa,et al. COVID‐19‐related neuropathology and microglial activation in elderly with and without dementia , 2021, Brain pathology.
[28] J. Saez-Rodriguez,et al. Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions , 2021, Immunity.
[29] B. Solarino,et al. Post-mortem persistence of SARS-CoV-2: a preliminary study , 2021, Forensic Science, Medicine and Pathology.
[30] A. Stalder,et al. Histomorphological patterns of regional lymph nodes in COVID-19 lungs , 2021, Der Pathologe.
[31] T. Cokelaer,et al. COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters , 2021, Science Translational Medicine.
[32] O. Pansarasa,et al. Detection of SARS-CoV-2 genome and whole transcriptome sequencing in frontal cortex of COVID-19 patients , 2021, Brain, Behavior, and Immunity.
[33] Xiaozhong Peng,et al. The olfactory route is a potential way for SARS-CoV-2 to invade the central nervous system of rhesus monkeys , 2021, Signal Transduction and Targeted Therapy.
[34] H. Takeda,et al. Activation of cholinergic system partially rescues olfactory dysfunction-induced learning and memory deficit in mice , 2021, Behavioural Brain Research.
[35] R. Sebra,et al. Pathophysiology of SARS-CoV-2: the Mount Sinai COVID-19 autopsy experience , 2021, Modern Pathology.
[36] N. Gassler,et al. Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and the correlation with tissue damage , 2021, eLife.
[37] M. Cominetti,et al. IL-6 and IL-10 are associated with disease severity and higher comorbidity in adults with COVID-19 , 2021, Cytokine.
[38] M. Boldrini,et al. How COVID-19 Affects the Brain. , 2021, JAMA psychiatry.
[39] T. Beach,et al. Acute Brain Ischemia, Infarction and Hemorrhage in Subjects Dying with or Without Autopsy-Proven Acute Pneumonia , 2021, medRxiv.
[40] A. Khandji,et al. COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital , 2021, medRxiv.
[41] H. Ebihara,et al. Comparison of In Situ Hybridization, Immunohistochemistry and Reverse Transcription-Droplet Digital Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-2)-Testing in Tissue. , 2021, Archives of pathology & laboratory medicine.
[42] C. Lodovichi,et al. Spontaneous Afferent Activity Carves Olfactory Circuits , 2021, Frontiers in Cellular Neuroscience.
[43] Valentina Perri,et al. Increased sCD163 and sCD14 Plasmatic Levels and Depletion of Peripheral Blood Pro-Inflammatory Monocytes, Myeloid and Plasmacytoid Dendritic Cells in Patients With Severe COVID-19 Pneumonia , 2021, Frontiers in Immunology.
[44] E. Engler-Chiurazzi,et al. SARS-CoV-2 mediated neuroinflammation and the impact of COVID-19 in neurological disorders , 2021, Cytokine & Growth Factor Reviews.
[45] T. Montine,et al. Mapping of SARS-CoV-2 Brain Invasion and Histopathology in COVID-19 Disease , 2021, medRxiv.
[46] W. Lau,et al. Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19 , 2021, Cell.
[47] D. Werring,et al. Characteristics of intracerebral haemorrhage associated with COVID-19: a systematic review and pooled analysis of individual patient and aggregate data , 2021, Journal of Neurology.
[48] L. Østergaard. SARS CoV‐2 related microvascular damage and symptoms during and after COVID‐19: Consequences of capillary transit‐time changes, tissue hypoxia and inflammation , 2021, Physiological reports.
[49] Á. Chamorro,et al. Stroke etiologies in patients with COVID-19: the SVIN COVID-19 multinational registry , 2021, BMC Neurology.
[50] T. Uyeki,et al. Evidence of SARS-CoV-2 Replication and Tropism in the Lungs, Airways and Vascular Endothelium of Patients with Fatal COVID-19: An Autopsy Case-Series. , 2021, The Journal of infectious diseases.
[51] D. Raoult,et al. 18F-FDG brain PET hypometabolism in patients with long COVID , 2021, European Journal of Nuclear Medicine and Molecular Imaging.
[52] L. Pantanowitz,et al. Postmortem Findings Associated With SARS-CoV-2 , 2021, The American journal of surgical pathology.
[53] S. Farhadian,et al. Neuroinvasion of SARS-CoV-2 in human and mouse brain , 2021, The Journal of experimental medicine.
[54] H. Shill,et al. Increased Risk of Autopsy-Proven Pneumonia with Sex, Season and Neurodegenerative Disease , 2021, medRxiv.
[55] Janna H. Neltner,et al. Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain , 2021, Neurobiology of Aging.
[56] S. Saffari,et al. Stroke as a Neurological Complication of COVID-19: A Systematic Review and Meta-Analysis of Incidence, Outcomes and Predictors , 2020, Journal of Stroke and Cerebrovascular Diseases.
[57] D. Hamer,et al. Neurologic Findings Among Inpatients With COVID-19 at a Safety-net US Hospital. , 2020, Neurology. Clinical practice.
[58] L. Santoro,et al. Impact of SARS-CoV-2 infection on the recovery of peripheral blood mononuclear cells by density gradient , 2020, Scientific Reports.
[59] Zulma Tovar-Spinoza,et al. Central and peripheral nervous system involvement by COVID-19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings , 2020, BMC Infectious Diseases.
[60] K. El-Salem,et al. Neurological manifestations and complications of coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis , 2020, BMC Neurology.
[61] D. Perl,et al. Microvascular Injury in the Brains of Patients with Covid-19 , 2020, The New England journal of medicine.
[62] Daeui Park,et al. Comparison of Digital PCR and Quantitative PCR with Various SARS-CoV-2 Primer-Probe Sets , 2020, Journal of microbiology and biotechnology.
[63] P. Tubert-Bitter,et al. Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study , 2020, The Lancet Respiratory Medicine.
[64] H. Diener,et al. COVID-19: patients with stroke or risk of stroke , 2020, European heart journal supplements : journal of the European Society of Cardiology.
[65] C. Conrad,et al. Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 , 2020, Nature Neuroscience.
[66] D. Kondziella,et al. Thirty-Day Mortality and Morbidity in COVID-19 Positive vs. COVID-19 Negative Individuals and vs. Individuals Tested for Influenza A/B: A Population-Based Study , 2020, Frontiers in Medicine.
[67] A. Aguzzi,et al. Intracerebral endotheliitis and microbleeds are neuropathological features of COVID‐19 , 2020, Neuropathology and applied neurobiology.
[68] C. Gerloff,et al. Frequent neurocognitive deficits after recovery from mild COVID-19 , 2020, Brain communications.
[69] H. Markus,et al. Stroke in COVID-19: A systematic review and meta-analysis , 2020, International journal of stroke : official journal of the International Stroke Society.
[70] A. Helenius,et al. Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity , 2020, Science.
[71] E. Keller,et al. Large and Small Cerebral Vessel Involvement in Severe COVID-19 , 2020, Stroke.
[72] F. D’Alessio,et al. COVID-19 and myeloid cells: complex interplay correlates with lung severity. , 2020, The Journal of clinical investigation.
[73] M. Aepfelbacher,et al. Neuropathology of patients with COVID-19 in Germany: a post-mortem case series , 2020, The Lancet Neurology.
[74] M. Kolb,et al. Inflammation and intussusceptive angiogenesis in COVID-19: everything in and out of flow , 2020, European Respiratory Journal.
[75] T. H. Santa Rita,et al. Analytical Sensitivity and Specificity of Two RT-qPCR Protocols for SARS-CoV-2 Detection Performed in an Automated Workflow , 2020, Genes.
[76] E. Pacary,et al. CaMKIIβ in Neuronal Development and Plasticity: An Emerging Candidate in Brain Diseases , 2020, International journal of molecular sciences.
[77] E. Aronica,et al. Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study , 2020, The Lancet Microbe.
[78] A. Tsatsakis,et al. Unraveling the Possible Routes of SARS-COV-2 Invasion into the Central Nervous System , 2020, Current Treatment Options in Neurology.
[79] S. Lesellier,et al. Hamster and ferret experimental infection with intranasal low dose of a single strain of SARS-CoV-2 , 2020, bioRxiv.
[80] M. Woodward,et al. Obesity as a risk factor for COVID‐19 mortality in women and men in the UK biobank: Comparisons with influenza/pneumonia and coronary heart disease , 2020, Diabetes, obesity & metabolism.
[81] G. J. Berry,et al. Development of a New Multiplex Real-Time RT-PCR Assay for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Detection , 2020, The Journal of Molecular Diagnostics : JMD.
[82] G. J. Berry,et al. Development of a New Multiplex Real Time RT-PCR Assay for SARS-CoV-2 Detection , 2020, The Journal of Molecular Diagnostics.
[83] J. Tripathy,et al. SeXX and COVID-19: tussle between the two. , 2020, Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace.
[84] E. Bullmore,et al. Invited Review: The spectrum of neuropathology in COVID‐19 , 2020, Neuropathology and applied neurobiology.
[85] E. Cudaback,et al. Commentary: APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort , 2020, Frontiers in Immunology.
[86] D. Menon,et al. Neuropathological findings in two patients with fatal COVID‐19 , 2020, Neuropathology and applied neurobiology.
[87] A. Borczuk,et al. COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City , 2020, Modern Pathology.
[88] S. Schwab,et al. Disseminated Multifocal Intracerebral Bleeding Events in Three Coronavirus Disease 2019 Patients on Extracorporeal Membrane Oxygenation As Rescue Therapy , 2020, Critical care explorations.
[89] L. Garavelli,et al. Severe intellectual disability, absence of language, epilepsy, microcephaly and progressive cerebellar atrophy related to the recurrent de novo variant p.(P139L) of the CAMK2B gene: A case report and brief review , 2020, American journal of medical genetics. Part A.
[90] P. Canoll,et al. Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage , 2020, Acta Neuropathologica Communications.
[91] K. Mertz,et al. Correlates of critical illness-related encephalopathy predominate postmortem COVID-19 neuropathology , 2020, Acta Neuropathologica.
[92] A. Nicholson,et al. Histopathological findings and viral tropism in UK patients with severe fatal COVID-19: a post-mortem study , 2020, The Lancet Microbe.
[93] M. Trauner,et al. Post-mortem viral dynamics and tropism in COVID-19 patients in correlation with organ damage , 2020, Virchows Archiv.
[94] Kelsey K. Finn,et al. Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19 , 2020, Cell.
[95] A. Baranova,et al. Comment on “ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank” by Kuo et al , 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.
[96] D. Melzer,et al. Response to Comment on “ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank” by Kuo et al. , 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.
[97] H. Sung,et al. Evaluation of Four Commercial Kits for SARS-CoV-2 Real-Time Reverse-Transcription Polymerase Chain Reaction Approved by Emergency-Use-Authorization in Korea , 2020, Frontiers in Medicine.
[98] A. Paetau,et al. Neuropathologic features of four autopsied COVID‐19 patients , 2020, Brain pathology.
[99] Eric Song,et al. Longitudinal analyses reveal immunological misfiring in severe COVID-19 , 2020, Nature.
[100] E. Brown,et al. Cerebral Microvascular Injury in Severe COVID-19 , 2020, medRxiv.
[101] E. Englund,et al. Cause of death in autopsy‐confirmed dementia disorders , 2020, European journal of neurology.
[102] D. Melzer,et al. Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort , 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.
[103] R. Hotchkiss,et al. Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections , 2020, JCI insight.
[104] B. Cucchiara,et al. Acute Cerebrovascular Events in Hospitalized COVID-19 Patients , 2020, Stroke.
[105] G. Lippi,et al. Diabetes mellitus association with coronavirus disease 2019 (COVID‐19) severity and mortality: A pooled analysis , 2020, Journal of diabetes.
[106] J. Lacy,et al. Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series , 2020, The Lancet.
[107] R. Faull,et al. Quantitative immunohistochemical analysis of myeloid cell marker expression in human cortex captures microglia heterogeneity with anatomical context , 2020, Scientific Reports.
[108] A. Allegra,et al. Coagulopathy and thromboembolic events in patients with SARS-CoV-2 infection: pathogenesis and management strategies , 2020, Annals of Hematology.
[109] Kenneth Lap-Kei Wu,et al. SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters , 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[110] J. Pariente,et al. COVID-19–associated acute necrotising encephalopathy successfully treated with steroids and polyvalent immunoglobulin with unusual IgG targeting the cerebral fibre network , 2020, Journal of Neurology, Neurosurgery, and Psychiatry.
[111] Z. Xia,et al. Obesity and mortality of COVID-19. Meta-analysis , 2020, Obesity Research & Clinical Practice.
[112] M. Shankar-Hari,et al. Microvascular injury and hypoxic damage: emerging neuropathological signatures in COVID-19 , 2020, Acta Neuropathologica.
[113] Marika M. Cusick,et al. Risk of Ischemic Stroke in Patients With Coronavirus Disease 2019 (COVID-19) vs Patients With Influenza. , 2020, JAMA neurology.
[114] Karlheinz Peter,et al. The Emerging Threat of (Micro)Thrombosis in COVID-19 and Its Therapeutic Implications , 2020, Circulation research.
[115] P. Matthews,et al. Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study , 2020, The Lancet Psychiatry.
[116] D. Melzer,et al. ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank , 2020, medRxiv.
[117] Ruth Levinson,et al. Time course of anosmia and dysgeusia in patients with mild SARS-CoV-2 infection , 2020, Infectious diseases.
[118] Imen Megdiche,et al. Brain MRI Findings in Severe COVID-19: A Retrospective Observational Study , 2020, Radiology.
[119] Pardis C Sabeti,et al. Neuropathological Features of Covid-19 , 2020, The New England journal of medicine.
[120] C. Majós,et al. Neurologic Involvement in COVID-19: Cause or Coincidence? A Neuroimaging Perspective , 2020, American Journal of Neuroradiology.
[121] V. Ojetti,et al. Clinical characteristics and prognostic factors in COVID‐19 patients aged ≥80 years , 2020, Geriatrics & gerontology international.
[122] K. Fukunaga,et al. Memantine Improves Depressive-like Behaviors via Kir6.1 Channel Inhibition in Olfactory Bulbectomized Mice , 2020, Neuroscience.
[123] M. Amin,et al. Fatal central nervous system co-infection with SARS-CoV-2 and tuberculosis in a healthy child , 2020, BMC Pediatrics.
[124] M. Aepfelbacher,et al. Dying with SARS-CoV-2 infection—an autopsy study of the first consecutive 80 cases in Hamburg, Germany , 2020, International Journal of Legal Medicine.
[125] M. Zervos,et al. Clinical Characteristics and Morbidity Associated With Coronavirus Disease 2019 in a Series of Patients in Metropolitan Detroit , 2020, JAMA network open.
[126] F. Neff,et al. Early evidence of pronounced brain involvement in fatal COVID-19 outcomes , 2020, The Lancet.
[127] T. Segura,et al. Neurologic manifestations in hospitalized patients with COVID-19 , 2020, Neurology.
[128] J. Vincent,et al. Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients , 2020, Critical Care.
[129] A. Radmanesh,et al. Brain Imaging Use and Findings in COVID-19: A Single Academic Center Experience in the Epicenter of Disease in the United States , 2020, American Journal of Neuroradiology.
[130] G. Manousakis,et al. Neurological involvement of coronavirus disease 2019: a systematic review , 2020, Journal of Neurology.
[131] V. Regitz-Zagrosek,et al. Impact of sex and gender on COVID-19 outcomes in Europe , 2020, Biology of Sex Differences.
[132] C. Lucchinetti,et al. Neuropathology of COVID-19: a spectrum of vascular and acute disseminated encephalomyelitis (ADEM)-like pathology , 2020, Acta Neuropathologica.
[133] R. Claus,et al. Postmortem Examination of Patients With COVID-19. , 2020, JAMA.
[134] K. Blennow,et al. Steroid‐Responsive Encephalitis in Coronavirus Disease 2019 , 2020, Annals of neurology.
[135] C. Mantzoros,et al. Severe obesity, increasing age and male sex are independently associated with worse in-hospital outcomes, and higher in-hospital mortality, in a cohort of patients with COVID-19 in the Bronx, New York , 2020, Metabolism.
[136] A. Engin,et al. Two important controversial risk factors in SARS-CoV-2 infection: Obesity and smoking , 2020, Environmental Toxicology and Pharmacology.
[137] C. Mantzoros,et al. Severe obesity is associated with higher in-hospital mortality in a cohort of patients with COVID-19 in the Bronx, New York , 2020, Metabolism.
[138] V. Chinchilli,et al. The association of cardiovascular disease and other pre-existing comorbidities with COVID-19 mortality: A systematic review and meta-analysis , 2020, medRxiv.
[139] Victor G. Puelles,et al. Multiorgan and Renal Tropism of SARS-CoV-2 , 2020, The New England journal of medicine.
[140] N. Trotta,et al. Early postmortem brain MRI findings in COVID-19 non-survivors , 2020, Neurology.
[141] M. Aepfelbacher,et al. Autopsy Findings and Venous Thromboembolism in Patients With COVID-19 , 2020, Annals of Internal Medicine.
[142] K. Mertz,et al. Postmortem examination of COVID‐19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction , 2020, Histopathology.
[143] S. Farmer,et al. Characteristics of ischaemic stroke associated with COVID-19 , 2020, Journal of Neurology, Neurosurgery, and Psychiatry.
[144] G. Lippi,et al. Association of Cardiovascular Disease With Coronavirus Disease 2019 (COVID-19) Severity: A Meta-Analysis , 2020, Current Problems in Cardiology.
[145] J. Sejvar,et al. Neurological associations of COVID-19 , 2020, The Lancet Neurology.
[146] Eun Ji Kim,et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. , 2020, JAMA.
[147] M. Fowkes,et al. Central nervous system involvement by severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) , 2020, Journal of medical virology.
[148] G. Lippi,et al. Cerebrovascular disease is associated with an increased disease severity in patients with Coronavirus Disease 2019 (COVID-19): A pooled analysis of published literature , 2020, International journal of stroke : official journal of the International Stroke Society.
[149] R. Butowt,et al. SARS-CoV-2: Olfaction, Brain Infection, and the Urgent Need for Clinical Samples Allowing Earlier Virus Detection , 2020, ACS chemical neuroscience.
[150] L. Mao,et al. Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China. , 2020, JAMA neurology.
[151] C. Eloit,et al. Sudden and Complete Olfactory Loss Function as a Possible Symptom of COVID-19. , 2020, JAMA otolaryngology-- head & neck surgery.
[152] D. Peschanski,et al. The potential genetic network of human brain SARS-CoV-2 infection , 2020, bioRxiv.
[153] N. Enomoto,et al. A first case of meningitis/encephalitis associated with SARS-Coronavirus-2 , 2020, International Journal of Infectious Diseases.
[154] P. Vollmar,et al. Virological assessment of hospitalized patients with COVID-2019 , 2020, Nature.
[155] N. Kabbani,et al. Does COVID19 Infect the Brain? If So, Smokers Might Be at a Higher Risk , 2020, Molecular Pharmacology.
[156] Suresh Patel,et al. COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features , 2020, Radiology.
[157] M. Heneka,et al. Do infections have a role in the pathogenesis of Alzheimer disease? , 2020, Nature Reviews Neurology.
[158] Sonja W. Scholz,et al. Human Herpesvirus 6 Detection in Alzheimer’s Disease Cases and Controls across Multiple Cohorts , 2020, Neuron.
[159] F. Schmitt,et al. Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome , 2020, Alzheimer's & dementia.
[160] Victor M Corman,et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR , 2020, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.
[161] Alain Le Coupanec,et al. Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? , 2019, Viruses.
[162] K. Leung,et al. Natural clinical course of progressive supranuclear palsy in Chinese patients in Hong Kong. , 2019, Hong Kong medical journal = Xianggang yi xue za zhi.
[163] V. Hespanhol,et al. Pneumonia mortality, comorbidities matter? , 2019, Pulmonology.
[164] A. Anzueto,et al. Association of atypical antipsychotics and mortality for patients hospitalised with pneumonia , 2019, ERJ Open Research.
[165] D. Seilhean. Infections of the central nervous system: Neuropathology. , 2019, Revue neurologique.
[166] P. Thomas,et al. Influenza virus-related critical illness: pathophysiology and epidemiology , 2019, Critical Care.
[167] C. Jack,et al. Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report , 2019, Brain : a journal of neurology.
[168] Manolis Kellis,et al. Single-cell transcriptomic analysis of Alzheimer’s disease , 2019, Nature.
[169] B. Yawn,et al. Patient-Reported Consequences of Community-Acquired Pneumonia in Patients with Chronic Obstructive Pulmonary Disease. , 2019, Chronic obstructive pulmonary diseases.
[170] K. Mizukami,et al. Pneumonia-associated death in patients with dementia: A systematic review and meta-analysis , 2019, PloS one.
[171] D. Frasca,et al. Influence of Obesity on Pneumococcus Infection Risk in the Elderly , 2019, Front. Endocrinol..
[172] J. Mizgerd. Inflammation and Pneumonia: Why Are Some More Susceptible than Others? , 2018, Clinics in chest medicine.
[173] M. Martinez,et al. The calendar of epidemics: Seasonal cycles of infectious diseases , 2018, PLoS pathogens.
[174] K. Yokochi,et al. De novo variants in CAMK2A and CAMK2B cause neurodevelopmental disorders , 2018, Annals of clinical and translational neurology.
[175] A. Inutsuka,et al. Sex differences in olfactory-induced neural activation of the amygdala , 2017, Behavioural Brain Research.
[176] H. Mukae,et al. Impact of the number of aspiration risk factors on mortality and recurrence in community-onset pneumonia , 2017, Clinical interventions in aging.
[177] Meghan C Towne,et al. De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability. , 2017, American journal of human genetics.
[178] Manoj Kumar,et al. INGE GRUNDKE-IQBAL AWARD FOR ALZHEIMER’S RESEARCH: NEUROTOXIC REACTIVE ASTROCYTES ARE INDUCED BY ACTIVATED MICROGLIA , 2019, Alzheimer's & Dementia.
[179] K. Fukunaga,et al. Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice , 2017, Pharmacology.
[180] T. Marrie,et al. Prognostic factors associated with mortality and major in-hospital complications in patients with bacteremic pneumococcal pneumonia , 2016, Medicine.
[181] Albert-László Barabási,et al. PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation , 2016, Nature Communications.
[182] S. Teramoto,et al. Prognostic Factors Related to Dementia with Lewy Bodies Complicated with Pneumonia: An Autopsy Study , 2016, Internal medicine.
[183] A. Darzi,et al. Outcomes of dementia: Systematic review and meta-analysis of hospital administrative database studies. , 2016, Archives of gerontology and geriatrics.
[184] Robert E. Schmidt,et al. A complement–microglial axis drives synapse loss during virus-induced memory impairment , 2016, Nature.
[185] Måns Magnusson,et al. MultiQC: summarize analysis results for multiple tools and samples in a single report , 2016, Bioinform..
[186] F. Sengpiel,et al. Immunization Against Specific Fragments of Neurotrophin p75 Receptor Protects Forebrain Cholinergic Neurons in the Olfactory Bulbectomized Mice , 2016, Journal of Alzheimer's disease : JAD.
[187] Chih-Jen Yang,et al. Risk factors for pneumonia among patients with Parkinson’s disease: a Taiwan nationwide population-based study , 2016, Neuropsychiatric disease and treatment.
[188] M. Tavakoli-Yaraki,et al. Effects of cannabinoids and their receptors on viral infections , 2016, Journal of medical virology.
[189] A. Barabasi,et al. PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation , 2016, Nature Communications.
[190] D. Chung,et al. Community-acquired pneumonia requiring hospitalization among U . S . adults , 2016 .
[191] Alan S. Brown,et al. Neurotropic virus infections as the cause of immediate and delayed neuropathology , 2015, Acta Neuropathologica.
[192] M. Holtzman,et al. PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection , 2015, Nature Immunology.
[193] H. Shill,et al. Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program , 2015, Neuropathology : official journal of the Japanese Society of Neuropathology.
[194] W. Self,et al. Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults. , 2015, The New England journal of medicine.
[195] Janna H. Neltner,et al. Disease-related microglia heterogeneity in the hippocampus of Alzheimer’s disease, dementia with Lewy bodies, and hippocampal sclerosis of aging , 2015, Acta Neuropathologica Communications.
[196] A. Regev,et al. Spatial reconstruction of single-cell gene expression , 2015, Nature Biotechnology.
[197] Matthew E. Ritchie,et al. limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.
[198] Michael J. Podolsky,et al. Circuit Formation and Function in the Olfactory Bulb of Mice with Reduced Spontaneous Afferent Activity , 2015, The Journal of Neuroscience.
[199] Thomas Wisniewski,et al. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy , 2015, Acta Neuropathologica.
[200] Janna H. Neltner,et al. Primary age-related tauopathy (PART): a common pathology associated with human aging , 2014, Acta Neuropathologica.
[201] Ruth E Martin,et al. A Systematic Review and Meta-Analysis Examining Pneumonia-Associated Mortality in Dementia , 2014, Dementia and Geriatric Cognitive Disorders.
[202] I. Bechmann,et al. Microglial pathology , 2014, Acta neuropathologica communications.
[203] H. Vinters,et al. Comorbidity in Dementia: Update of an Ongoing Autopsy Study , 2014, Journal of the American Geriatrics Society.
[204] David W. Holman,et al. Viral Pathogen-Associated Molecular Patterns Regulate Blood-Brain Barrier Integrity via Competing Innate Cytokine Signals , 2014, mBio.
[205] Charity W. Law,et al. voom: precision weights unlock linear model analysis tools for RNA-seq read counts , 2014, Genome Biology.
[206] D. Finn,et al. Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala , 2013, Genes, brain, and behavior.
[207] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..
[208] Allan R. Jones,et al. An anatomically comprehensive atlas of the adult human brain transcriptome , 2012, Nature.
[209] D. Murdoch,et al. The role of postmortem studies in pneumonia etiology research. , 2012, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[210] J. Schneider,et al. National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease , 2012, Alzheimer's & Dementia.
[211] Amos D. Korczyn,et al. Vascular dementia , 1993, Journal of the Neurological Sciences.
[212] J. Trojanowski,et al. A harmonized classification system for FTLD-TDP pathology , 2011, Acta Neuropathologica.
[213] M. Diksic,et al. Upregulated arachidonic acid signalling in the olfactory bulbectomized rat model of depression , 2011, Neurochemistry International.
[214] Charles Duyckaerts,et al. National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach , 2011, Acta Neuropathologica.
[215] D. Dickson,et al. Neuropathology of variants of progressive supranuclear palsy. , 2010, Current opinion in neurology.
[216] Thomas Gasser,et al. Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria , 2009, The Lancet Neurology.
[217] Cécile Viboud,et al. Influenza seasonality: Lifting the fog , 2009, Proceedings of the National Academy of Sciences.
[218] R. Webster,et al. Viral parkinsonism. , 2009, Biochimica et biophysica acta.
[219] Steve Horvath,et al. WGCNA: an R package for weighted correlation network analysis , 2008, BMC Bioinformatics.
[220] Anthony S Fauci,et al. Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness. , 2008, The Journal of infectious diseases.
[221] M. Diksic,et al. Olfactory bulbectomy reduces cerebral glucose utilization: 2-[14C]deoxyglucose autoradiographic study , 2008, Brain Research Bulletin.
[222] David K. Meyerholz,et al. Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2 , 2008, Journal of Virology.
[223] A. Fertala,et al. Type I collagen and collagen mimetics as angiogenesis promoting superpolymers. , 2007, Current pharmaceutical design.
[224] Peter Langfelder,et al. Eigengene networks for studying the relationships between co-expression modules , 2007, BMC Systems Biology.
[225] V. Koliatsos,et al. NMDA inhibitors cause apoptosis of pyramidal neurons in mature piriform cortex: Evidence for a nitric oxide-mediated effect involving inhibitory interneurons , 2007, Neuropharmacology.
[226] Dennis W Dickson,et al. Progressive Supranuclear Palsy: Pathology and Genetics , 2007, Brain pathology.
[227] A. Puche,et al. Odorant Deprivation Reversibly Modulates Transsynaptic Changes in the NR2B-Mediated CREB Pathway in Mouse Piriform Cortex , 2006, The Journal of Neuroscience.
[228] M. Onofrj,et al. Diagnosis and management of dementia with Lewy bodies: Third report of the DLB Consortium , 2006, Neurology.
[229] D. Dickson,et al. Hereditary diffuse leukoencephalopathy with spheroids: clinical, pathologic and genetic studies of a new kindred , 2006, Acta Neuropathologica.
[230] S Minoshima,et al. Diagnosis and management of dementia with Lewy bodies , 2005, Neurology.
[231] S. Horvath,et al. Statistical Applications in Genetics and Molecular Biology , 2011 .
[232] U Nath,et al. Population based mortality and quality of death certification in progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) , 2005, Journal of Neurology, Neurosurgery & Psychiatry.
[233] K. Jellinger,et al. Cause of death in demented and non-demented elderly inpatients; an autopsy study of 308 cases. , 2005, Journal of Alzheimer's disease : JAD.
[234] D. Dickson. Required techniques and useful molecular markers in the neuropathologic diagnosis of neurodegenerative diseases , 2005, Acta Neuropathologica.
[235] T. Dawson,et al. Cortical interneurons become activated by deafferentation and instruct the apoptosis of pyramidal neurons. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[236] J. Olsson,et al. Survival time, mortality, and cause of death in elderly patients with Parkinson's disease. A 9‐year follow‐up , 2003, Movement disorders : official journal of the Movement Disorder Society.
[237] C. H. Leung,et al. Trans-neuronal regulation of cortical apoptosis in the adult rat olfactory system , 2003, Brain Research.
[238] Xinde Wang,et al. Clinical course and cause of death in elderly patients with idiopathic Parkinson's disease. , 2002, Chinese medical journal.
[239] G. Clermont,et al. Hospitalized community-acquired pneumonia in the elderly: age- and sex-related patterns of care and outcome in the United States. , 2002, American journal of respiratory and critical care medicine.
[240] J. Newcombe,et al. Neuroinvasion by Human Respiratory Coronaviruses , 2000, Journal of Virology.
[241] S. Small,et al. Pattern of olfactory bulb innervation returns after recovery from reversible peripheral deafferentation , 2000, The Journal of comparative neurology.
[242] C. A. Byrd. Deafferentation-induced changes in the olfactory bulb of adult zebrafish , 2000, Brain Research.
[243] J. Korf,et al. Prolonged c-Jun expression in the basolateral amygdala following bulbectomy: possible implications for antidepressant activity and time of onset. , 2000, Brain research. Molecular brain research.
[244] S. Gilman,et al. Diagnostic criteria for Parkinson disease. , 1999, Archives of neurology.
[245] C. Marra,et al. Infections of the central nervous system. , 1991, Advances in internal medicine.
[246] V E Koliatsos,et al. Deafferentation Causes Apoptosis in Cortical Sensory Neurons in the Adult Rat , 1997, The Journal of Neuroscience.
[247] J. Kelly,et al. The olfactory bulbectomized rat as a model of depression: an update. , 1997, Pharmacology & therapeutics.
[248] R. Kream,et al. Olfactory marker protein (OMP) gene deletion causes altered physiological activity of olfactory sensory neurons. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[249] I Litvan,et al. Natural history of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) and clinical predictors of survival: a clinicopathological study. , 1996, Journal of neurology, neurosurgery, and psychiatry.
[250] J. Kauer,et al. Olfactory marker protein mRNA is found in axons of olfactory receptor neurons , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[251] G. Wilcock,et al. Latent herpes simplex virus type 1 in normal and Alzheimer's disease brains , 1991, Journal of medical virology.
[252] A. Fasolo,et al. Carnosine-, calcitonin gene-related peptide- and tyrosine hydroxylase-immunoreactivity in the mouse olfactory bulb following peripheral denervation , 1990, Brain Research.
[253] Y. Khew-Goodall,et al. Neuroplasticity in the olfactory system: Differential effects of central and peripheral lesions of the primary olfactory pathway on the expression of B‐50/GAP43 and the olfactory marker protein , 1990, Journal of neuroscience research.
[254] T. Crow,et al. Herpes simplex virus: a role in the aetiology of Alzheimer's disease? , 1986, Journal of neurology, neurosurgery, and psychiatry.
[255] B. Leonard. The olfactory bulbectomized rat as a model of depression. , 1984, Polish journal of pharmacology and pharmacy.
[256] F. Margolis. Olfactory Marker Protein (OMP) , 1982, Scandinavian journal of immunology. Supplement.
[257] D. Gilden,et al. Herpes simplex type 1 DNA in human brain tissue. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[258] P. Yates,et al. Viruses, Parkinsonism and Alzheimer's disease. , 1981, Journal of neurology, neurosurgery, and psychiatry.
[259] R. Sutton,et al. DETECTION OF HERPES-SIMPLEX VIRAL GENOME IN BRAIN TISSUE , 1979, The Lancet.
[260] P. Graziadei,et al. Immunocytochemistry of the olfactory marker protein. , 1977, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[261] M. Yahr,et al. Influenza virus antigen in postencephalitic parkinsonism brain. Detection by immunofluorescence. , 1974, Archives of neurology.