Vardenafil decreases bladder afferent nerve activity in unanesthetized, decerebrate, spinal cord-injured rats.

[1]  D. Behr-Roussel,et al.  Nitric oxide/cyclic guanosine monophosphate signalling mediates an inhibitory action on sensory pathways of the micturition reflex in the rat. , 2010, European urology.

[2]  Scott Haughie,et al.  A placebo‐controlled study investigating the efficacy and safety of the phosphodiesterase type 5 inhibitor UK‐369,003 for the treatment of men with lower urinary tract symptoms associated with clinical benign prostatic hyperplasia , 2010, BJU international.

[3]  P. Validire,et al.  Signalling pathways involved in sildenafil‐induced relaxation of human bladder dome smooth muscle , 2010, British journal of pharmacology.

[4]  Naoki Yoshimura,et al.  Changes in afferent activity after spinal cord injury , 2010, Neurourology and urodynamics.

[5]  M. Carini,et al.  Acute vardenafil administration improves bladder oxygenation in spontaneously hypertensive rats. , 2010, The journal of sexual medicine.

[6]  J. Wyndaele,et al.  Mechanosensitive primary bladder afferent activity in rats with and without spinal cord transection. , 2009, The Journal of urology.

[7]  J. de Vente,et al.  On the origins of the sensory output from the bladder: the concept of afferent noise , 2009, BJU international.

[8]  C. Roehrborn,et al.  Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: a dose finding study. , 2008, The Journal of urology.

[9]  M. Chancellor,et al.  Nitric oxide-mediated suppression of detrusor overactivity by arginase inhibitor in rats with chronic spinal cord injury. , 2008, Urology.

[10]  C. Stief,et al.  A randomised, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia. , 2008, European urology.

[11]  M. Carini,et al.  Vardenafil improves urodynamic parameters in men with spinal cord injury: results from a single dose, pilot study. , 2007, The Journal of urology.

[12]  K. Kihara,et al.  Inhibitory roles of peripheral nitrergic mechanisms in capsaicin‐induced detrusor overactivity in the rat , 2007, BJU international.

[13]  W. C. Groat,et al.  Role of spinal metabotropic glutamate receptors in regulation of lower urinary tract function in the decerebrate unanesthetized rat , 2007, Neuroscience Letters.

[14]  M. Carini,et al.  Characterization and functional role of androgen-dependent PDE5 activity in the bladder. , 2007, Endocrinology.

[15]  K. McVary,et al.  Sildenafil citrate improves erectile function and urinary symptoms in men with erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia: a randomized, double-blind trial. , 2007, The Journal of urology.

[16]  R. Persad,et al.  PRE‐CLINICAL EVIDENCE FOR THE USE OF PHOSPHODIESTERASE‐5 INHIBITORS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND LOWER URINARY TRACT SYMPTOMS , 2006, BJU international.

[17]  Emmanuel Chartier-Kastler,et al.  Prevention of urinary tract infection in spinal cord-injured patients: safety and efficacy of a weekly oral cyclic antibiotic (WOCA) programme with a 2 year follow-up--an observational prospective study. , 2006, The Journal of antimicrobial chemotherapy.

[18]  S. Matsuura,et al.  Afferent fibers of the hypogastric nerves are involved in the facilitating effects of chemical bladder irritation in rats. , 2001, Journal of neurophysiology.

[19]  W. C. Groat,et al.  Nitric Oxide Modulates Ca2+ Channels in Dorsal Root Ganglion Neurons Innervating Rat Urinary Bladder , 2001 .

[20]  A. Brading,et al.  The effect of bladder outflow obstruction on detrusor blood flow changes during the voiding cycle in conscious pigs. , 2001, The Journal of urology.

[21]  W. C. Groat,et al.  Effect of intravesical nitric oxide therapy on cyclophosphamide-induced cystitis. , 1999, The Journal of urology.

[22]  S. Snyder,et al.  Urinary bladder-urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase models idiopathic voiding disorders in humans , 1997, Nature Medicine.

[23]  N. Moss,et al.  Pressure, volume, and chemosensitivity in afferent innervation of urinary bladder in rats. , 1997, The American journal of physiology.

[24]  G. Gebhart,et al.  Mechanosensitive properties of pelvic nerve afferent fibers innervating the urinary bladder of the rat. , 1994, Journal of neurophysiology.

[25]  J. Armour,et al.  Mechanoreceptor afferent activity compared with receptor field dimensions and pressure changes in feline urinary bladder. , 1992, Canadian journal of physiology and pharmacology.

[26]  K. Andersson,et al.  Inhibition of the arginine/nitric oxide pathway causes bladder hyperactivity in the rat. , 1992, Acta physiologica Scandinavica.

[27]  I. Nadelhaft,et al.  Conduction velocity distribution of afferent fibers innervating the rat urinary bladder , 1990, Brain Research.

[28]  A. Krieger,et al.  Procedure for the decerebration of the rat , 1978, Brain Research Bulletin.

[29]  W E Bradley,et al.  Distribution of lumbar and sacral afferent axons in submucosa of cat urinary bladder , 1975, The Anatomical record.

[30]  M. Talaat.  Afferent impulses in the nerves supplying the urinary bladder , 1937, The Journal of physiology.

[31]  J. Evans,et al.  Observations on the nerves of supply to the bladder and urethra of the cat, with a study of their action potentials , 1936, The Journal of physiology.