Osthole relieves skin damage and inhibits chronic itch through modulation of Akt/ZO-3 pathway in atopic dermatitis.

[1]  Yuan Zhou,et al.  mMrgprA3/mMrgprC11/hMrgprX1: Potential therapeutic targets for allergic contact dermatitis–induced pruritus in mice and humans , 2022, Contact dermatitis.

[2]  Yuan Zhou,et al.  Beneficial Effects of Quercetin on Microcystin-LR Induced Tight Junction Defects , 2021, Frontiers in Pharmacology.

[3]  S. Choung,et al.  Lithospermum erythrorhizon Alleviates Atopic Dermatitis-like Skin Lesions by Restoring Immune Balance and Skin Barrier Function in 2.4-Dinitrochlorobenzene-Induced NC/Nga Mice , 2021, Nutrients.

[4]  X. Zhang,et al.  Scratching damages tight junctions through the Akt–claudin 1 axis in atopic dermatitis , 2020, Clinical and experimental dermatology.

[5]  K. Na,et al.  Oral treatment with Aloe polysaccharide ameliorates ovalbumin‐induced atopic dermatitis by restoring tight junctions in skin , 2019, Scandinavian journal of immunology.

[6]  Xingkai Zhang,et al.  The effects of tranylcypromine on osteoclastogenesis in vitro and in vivo , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[7]  Xiangping Fu,et al.  Osthole attenuates mouse atopic dermatitis by inhibiting thymic stromal lymphopoietin production from keratinocytes , 2019, Experimental dermatology.

[8]  A. Honigmann,et al.  Phase Separation of Zonula Occludens Proteins Drives Formation of Tight Junctions , 2019, Cell.

[9]  Hyo-soon Jeong,et al.  LGI3 promotes human keratinocyte differentiation via the Akt pathway , 2018, Experimental dermatology.

[10]  Kewei Wang,et al.  Antipruritic Effect of Natural Coumarin Osthole through Selective Inhibition of Thermosensitive TRPV3 Channel in the Skin , 2018, Molecular Pharmacology.

[11]  A. Kubo,et al.  Maintenance of tight junction barrier integrity in cell turnover and skin diseases , 2018, Experimental dermatology.

[12]  J. Kim,et al.  IL-33 down-regulates CLDN1 expression through the ERK/STAT3 pathway in keratinocytes. , 2018, Journal of dermatological science.

[13]  Yuan Zhou,et al.  Essential roles of Akt/Snail pathway in microcystin-LR-induced tight junction toxicity in Sertoli cell. , 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[14]  C. Flohr,et al.  When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council , 2017, Journal of the American Academy of Dermatology.

[15]  M. Jücker,et al.  Tight Junction Proteins Claudin-1 and Occludin Are Important for Cutaneous Wound Healing. , 2017, The American journal of pathology.

[16]  C. Akdis,et al.  Platelet-activating factor decreases skin keratinocyte tight junction barrier integrity. , 2016, The Journal of allergy and clinical immunology.

[17]  S. Tsukita,et al.  Dose-dependent role of claudin-1 in vivo in orchestrating features of atopic dermatitis , 2016, Proceedings of the National Academy of Sciences.

[18]  D. Santoro,et al.  A comparative study of epidermal tight junction proteins in a dog model of atopic dermatitis. , 2016, Veterinary dermatology.

[19]  S. Breton,et al.  The MAPK/ERK-Signaling Pathway Regulates the Expression and Distribution of Tight Junction Proteins in the Mouse Proximal Epididymis , 2015, Biology of reproduction.

[20]  E. Kostyra,et al.  Impact of fexofenadine, osthole and histamine on peripheral blood mononuclear cell proliferation and cytokine secretion. , 2015, European journal of pharmacology.

[21]  Ho Yee Cheung,et al.  Osthole: A Review on Its Bioactivities, Pharmacological Properties, and Potential as Alternative Medicine , 2015, Evidence-based complementary and alternative medicine : eCAM.

[22]  Hiroshi Suzuki,et al.  Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin , 2015, Science.

[23]  H. Williams,et al.  The Harmonizing Outcome Measures for Eczema (HOME) roadmap: a methodological framework to develop core sets of outcome measurements in dermatology. , 2015, The Journal of investigative dermatology.

[24]  U. Hasler,et al.  Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion , 2014, Cell cycle.

[25]  K. Ebnet JAM-A and aPKC , 2013, Tissue barriers.

[26]  E. Simpson,et al.  Eczema prevalence in the United States: data from the 2003 National Survey of Children's Health. , 2011, The Journal of investigative dermatology.

[27]  W. Hunziker,et al.  Tjp3/zo-3 is critical for epidermal barrier function in zebrafish embryos. , 2008, Developmental biology.

[28]  T. Matsui,et al.  ZO-1 and ZO-2 Independently Determine Where Claudins Are Polymerized in Tight-Junction Strand Formation , 2006, Cell.

[29]  C. V. Van Itallie,et al.  Claudins and epithelial paracellular transport. , 2006, Annual review of physiology.

[30]  A. Nusrat,et al.  Tight junctions and cell-cell interactions. , 2006, Methods in molecular biology.

[31]  G. Yosipovitch Dry skin and impairment of barrier function associated with itch – new insights , 2004, International journal of cosmetic science.

[32]  M. Itoh,et al.  Expression and distribution of ZO‐3, a tight junction MAGUK protein, in mouse tissues , 2003, Genes to cells : devoted to molecular & cellular mechanisms.

[33]  S. Tsukita,et al.  Claudin-based barrier in simple and stratified cellular sheets. , 2002, Current opinion in cell biology.

[34]  S. Peltonen,et al.  Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin and in vitro differentiating keratinocytes. , 2001, The Journal of investigative dermatology.

[35]  Shoichiro Tsukita,et al.  Multifunctional strands in tight junctions , 2001, Nature Reviews Molecular Cell Biology.

[36]  J. Istvan,et al.  The prevalence of atopic dermatitis in Oregon schoolchildren. , 2000, Journal of the American Academy of Dermatology.