Multilevel hybrid 2D strain imaging algorithm for ultrasound sector/phased arrays.

Two-dimensional (2D) cross-correlation algorithms are necessary to estimate local displacement vector information for strain imaging. However, most of the current two-dimensional cross-correlation algorithms were developed for linear array transducers. Although sector and phased array transducers are routinely used for clinical imaging of abdominal and cardiac applications, strain imaging for these applications has been performed using one-dimensional (1D) cross-correlation analysis. However, one-dimensional cross-correlation algorithms are unable to provide accurate and precise strain estimation along all the angular insonification directions which can range from -45 degrees to 45 degrees with sector and phased array transducers. In addition, since sector and phased array based images have larger separations between beam lines as the pulse propagates deeper into tissue, signal decorrelation artifacts with deformation or tissue motion are more pronounced. In this article, the authors propose a multilevel two-dimensional hybrid algorithm for ultrasound sector and phased array data that demonstrate improved tracking and estimation performance when compared to the traditional 1D cross-correlation or 2D cross-correlation based methods. Experimental results demonstrate that the signal-to-noise and contrast-to-noise ratio estimates improve significantly for smaller window lengths for the hybrid method when compared to the currently used one-dimensional or two-dimensional cross-correlation algorithms. Strain imaging results on ex vivo thermal lesions created in liver tissue and in vivo on cardiac short-axis views demonstrate the improved image quality obtained with this method.

[1]  T. Varghese,et al.  Normal and shear strain estimation using beam steering on linear-array transducers. , 2007, Ultrasound in medicine & biology.

[2]  T. Varghese,et al.  Two-dimensional multi-level strain estimation for discontinuous tissue , 2007, Physics in medicine and biology.

[3]  T. Varghese,et al.  Improvement of elastographic displacement estimation using a two-step cross-correlation method. , 2007, Ultrasound in medicine & biology.

[4]  Frédérique Frouin,et al.  Ultrasound elastography based on multiscale estimations of regularized displacement fields , 2004, IEEE Transactions on Medical Imaging.

[5]  J. Ophir,et al.  Elastography: Elasticity Imaging Using Ultrasound with Application to Muscle and Breast in Vivo , 1993, Ultrasonic imaging.

[6]  Tomy Varghese,et al.  Second Prize: Elastographic Measurements of in-Vivo Radiofrequency Ablation Lesions of the Kidney , 2006 .

[7]  Michel Bertrand,et al.  Noninvasive vascular elastography: theoretical framework , 2004, IEEE Transactions on Medical Imaging.

[8]  J. Ophir,et al.  A new elastographic method for estimation and imaging of lateral displacements, lateral strains, corrected axial strains and Poisson's ratios in tissues. , 1998, Ultrasound in medicine & biology.

[9]  J Ophir,et al.  An analysis of elastographic contrast-to-noise ratio. , 1998, Ultrasound in medicine & biology.

[10]  J. Ophir,et al.  Elastography: A Quantitative Method for Imaging the Elasticity of Biological Tissues , 1991, Ultrasonic imaging.

[11]  Yanning Zhu,et al.  A Modified Block Matching Method for Real-Time Freehand Strain Imaging , 2002, Ultrasonic imaging.

[12]  L. Wilson,et al.  Spectral tissue strain: a new technique for imaging tissue strain using intravascular ultrasound. , 1994, Ultrasound in medicine & biology.

[13]  M. O’Donnell,et al.  Internal displacement and strain imaging using ultrasonic speckle tracking , 1994, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[14]  M. Bilgen,et al.  Deformation models and correlation analysis in elastography. , 1996, The Journal of the Acoustical Society of America.

[15]  Tomy Varghese,et al.  Ultrasound frame rate requirements for cardiac elastography: experimental and in vivo results. , 2009, Ultrasonics.

[16]  Tomy Varghese,et al.  Three-dimensional electrode displacement elastography using the Siemens C7F2 fourSight four-dimensional ultrasound transducer. , 2008, Ultrasound in medicine & biology.

[17]  J Jiang,et al.  A parallelizable real-time motion tracking algorithm with applications to ultrasonic strain imaging , 2007, Physics in medicine and biology.

[18]  J. Ophir,et al.  Reduction of Image Noise in Elastography , 1993 .

[19]  T. Varghese,et al.  Tissue-Mimicking Oil-in-Gelatin Dispersions for Use in Heterogeneous Elastography Phantoms , 2003, Ultrasonic imaging.

[20]  J Ophir,et al.  Elastographic Imaging Using Staggered Strain Estimates , 2002, Ultrasonic imaging.

[21]  T. Hall,et al.  2-D companding for noise reduction in strain imaging , 1998, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[22]  Tomy Varghese,et al.  Elastographic versus x-ray CT imaging of radio frequency ablation coagulations: an in vitro study. , 2004, Medical physics.

[23]  J. Hossack,et al.  3D prostate elastography: algorithm, simulations and experiments , 2007, Physics in medicine and biology.

[24]  T. Varghese,et al.  Multiresolution imaging in elastography , 1998, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[25]  P L Carson,et al.  Ultrasound tissue displacement imaging with application to breast cancer. , 1995, Ultrasound in medicine & biology.

[26]  T. Varghese,et al.  A theoretical framework for performance characterization of elastography: the strain filter , 1997, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[27]  Michael F. Insana,et al.  Strain Imaging with a Deformable Mesh , 1999, Ultrasonic imaging.

[28]  T. Varghese,et al.  Elastographic measurement of the area and volume of thermal lesions resulting from radiofrequency ablation: pathologic correlation. , 2003, AJR. American journal of roentgenology.

[29]  H. Ermert,et al.  A time-efficient and accurate strain estimation concept for ultrasonic elastography using iterative phase zero estimation , 1999, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[30]  Tomy Varghese,et al.  Estimation of displacement vectors and strain tensors in elastography using angular insonifications , 2004 .