A possible translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase induction by ML-236b(compactin) in isolated rat hepatocytes.

[1]  P. Edwards,et al.  Properties of purified rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and regulation of enzyme activity. , 1980, The Journal of biological chemistry.

[2]  H. Okamoto,et al.  Translational control of proinsulin synthesis by glucose , 1980, Nature.

[3]  Endo Akira,et al.  Effects of ML-236B on cholesterol metabolism in mice and rats: Lack of hypocholesterolemic activity in normal animals , 1979 .

[4]  H. Mabuchi,et al.  Regulation of fatty acid synthesis in isolated hepatocytes by intestinal chylomicrons and their remnants , 1979, FEBS letters.

[5]  D. Galton,et al.  Regulation of sterol synthesis in human lymphocytes: evidence for post-transcriptional control by low density lipoprotein. , 1979, Biochimica et biophysica acta.

[6]  M. Brown,et al.  Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase. , 1978, The Journal of biological chemistry.

[7]  Y. Tsujita,et al.  Inhibition of cholesterol synthesis in vitro and in vivo by ML-236A and ML-236B, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. , 1977, European journal of biochemistry.

[8]  R. Schimke,et al.  Micro assay for 3-hydroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblasts. , 1974, Biochimica et biophysica acta.

[9]  J. Watson,et al.  Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins. , 1974, The Journal of biological chemistry.

[10]  P. Edwards,et al.  Dependence of the circadian rhythm of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A on ribonucleic acid synthesis. A possible second site of inhibition by dietary cholesterol. , 1974, The Journal of biological chemistry.

[11]  M. Brown,et al.  Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia. , 1974, The Journal of biological chemistry.

[12]  P. Edwards,et al.  Turnover rate of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase as determined by use of cycloheximide. , 1972, The Journal of biological chemistry.

[13]  M. Permutt,et al.  Insulin biosynthesis. II. Effect of glucose on ribonucleic acid synthesis in isolated rat islets. , 1972, The Journal of biological chemistry.

[14]  D. J. Shapiro,et al.  Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol synthesis. , 1971, The Journal of biological chemistry.

[15]  V. Rodwell,et al.  Diurnal variation and cholesterol regulation of hepatic HMG-CoA reductase activity. , 1969, Biochemical and biophysical research communications.

[16]  A. Kandutsch,et al.  Prevention of cyclic and triton-induced increases in hydroxymethylglutaryl coenzyme A reductase and sterol synthesis by puromycin. , 1969, The Journal of biological chemistry.

[17]  P. Edwards.  The influence of catecholamines and cyclic AMP on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and lipid biosynthesis in isolated rat hepatocytes. , 1975, Archives of biochemistry and biophysics.

[18]  S. Shefer,et al.  Determination of hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity in man. , 1974, Journal of lipid research.