Subacute Combined Degeneration of the Spinal Cord: Detection of preferential involvement of the fasciculus cuneatus using MRI

The patient was a 68-year-old man, hospitalized due to subacute onset of finger ataxia and gait disturbance. Laboratory examination revealed macrocytic anemia, decreased level of serum vitamin B12, and the presence of antiparietal and antiintrinsic factor antibodies. High signal intensity was observed in the fasciculus cuneatus of the spinal cord on T2-weighted MRI. Intramuscular injection of vitamin B12 resulted in reduction of intensity lesion on MRI and improvement of symptoms.

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