Impact of Transcendental Meditation on cardiovascular function at rest and during acute stress in adolescents with high normal blood pressure.

OBJECTIVE This study examined the impact of the Transcendental Meditation (TM) program on cardiovascular (CV) reactivity in adolescents with high normal BP. METHOD Thirty-five adolescents [34 African Americans (AAs), 1 Caucasian American (CA); ages 15-18 years] with resting systolic blood pressure (SBP) between the 85th and 95th percentile for their age and gender on three consecutive occasions, were randomly assigned to either TM (n=17) or health education control (CTL, n=18) groups. The TM group engaged in 15-min meditation twice each day for 2 months including sessions during school lunch break. Primary CV outcome measures were changes in blood pressure (BP), heart rate (HR), and cardiac output (CO) at rest and in response to two laboratory stressors, a simulated car driving stressor and an interpersonal social stressor interview. RESULTS The TM group exhibited greater decreases in resting SBP (P<.03) from pre- to postintervention, compared to the CTL group. The TM group exhibited greater decreases from pre- to postintervention in SBP, HR, and CO reactivity (P's<.03) to the simulated car driving stressor, and in SBP reactivity (P<.03) to the social stressor interview. CONCLUSION The TM program appears to have a beneficial impact upon CV functioning at rest and during acute laboratory stress in adolescents at-risk for hypertension.

[1]  R. Waziri,et al.  A controlled study of the effects of the Transcendental Meditation program on cardiovascular reactivity and ambulatory blood pressure. , 1997, The International journal of neuroscience.

[2]  K. Kolodner,et al.  Social competence interview for assessing physiological reactivity in adolescents. , 1991, Psychosomatic medicine.

[3]  F. Treiber,et al.  Noninvasive assessment of cardiac output in children using impedance cardiography. , 1990, American heart journal.

[4]  N. Schneiderman,et al.  Myocardial and peripheral vascular responses to behavioral challenges and their stability in black and white Americans. , 1992, Psychophysiology.

[5]  F. Treiber,et al.  Relationships between children's cardiovascular stress responses and resting cardiovascular functioning 1 year later. , 1997, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[6]  A. Hofman,et al.  The natural history of blood pressure in childhood. , 1985, International journal of epidemiology.

[7]  P. Whelton,et al.  A comparison of two automated monitors in the measurement of blood pressure reactivity. Trials of Hypertension Prevention Collaborative Research Group. , 1990, Annals of epidemiology.

[8]  H. Myers,et al.  Effects of stress reduction on carotid atherosclerosis in hypertensive African Americans. , 2000, Stroke.

[9]  G. Berenson,et al.  Epidemiology of early primary hypertension and implications for prevention: the Bogalusa Heart Study. , 1994, Journal of human hypertension.

[10]  F. Treiber,et al.  Acute effects of transcendental meditation on hemodynamic functioning in middle-aged adults. , 1999, Psychosomatic medicine.

[11]  R. Waziri,et al.  Effects of the transcendental meditation program on adaptive mechanisms: Changes in hormone levels and responses to stress after 4 months of practice , 1997, Psychoneuroendocrinology.

[12]  A. Wilson,et al.  Adrenocortical activity during meditation , 1978, Hormones and Behavior.

[13]  K. Matthews,et al.  Cardiovascular Responses to Behavioral Stress and Hypertension: a Meta-Analytic Review , 1990 .

[14]  B. Alpert,et al.  Racial aspects of blood pressure in children and adolescents. , 1993, Pediatric clinics of North America.

[15]  A. Jatene,et al.  A clinical comparison between cardiac output measured by thermodilution versus noninvasive thoracic electrical bioimpedance. , 1986, Acute care.

[16]  E. Langer,et al.  Transcendental meditation, mindfulness, and longevity: an experimental study with the elderly. , 1989, Journal of personality and social psychology.

[17]  U. Ebbecke [Physiology of consciousness]. , 1957, Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere.

[18]  D. Goleman,et al.  Meditation as an intervention in stress reactivity. , 1976, Journal of consulting and clinical psychology.

[19]  E. Geus Cardiovascular Reactivity to Psychological Stress and Disease J. Blascovich and E.S. Katkin (Eds.), APA, Washington, DC, 1993, pp. xv + 242, £35.95. ISBN 1-55798-192-2 , 1997, Biological Psychology.

[20]  C. Berkey,et al.  Cognitive Behavioral Techniques for Hypertension: Are They Effective? , 1993, Annals of Internal Medicine.

[21]  W R Holt,et al.  Transcendental Meditation vs Pseudo-Meditation on Visual Choice Reaction Time , 1978, Perceptual and motor skills.

[22]  J. Dimsdale,et al.  Temporal stability of task-induced cardiovascular, adrenergic, and psychological responses: the effects of race and hypertension. , 1993, Psychophysiology.

[23]  Relaxation training combined with increased physical activity lowers the psychophysiological activation in community-home boys. , 1990, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[24]  F. Treiber,et al.  Young Children'S Cardiovascular Stress Responses Predict Resting Cardiovascular Functioning 2 1/2 Years Later , 1996, Journal of cardiovascular risk.

[25]  M. McNeilly,et al.  Autonomic reactivity and hypertension in blacks: a review and proposed model. , 1991, Ethnicity & disease.

[26]  M. McNeilly,et al.  A biopsychosocial model of race differences in vascular reactivity. , 1993 .

[27]  A. Sherwood,et al.  Race and gender comparisons: I. Hemodynamic responses to a series of stressors. , 1993, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[28]  A. Sherwood,et al.  Race, borderline hypertension, and hemodynamic responses to behavioral stress before and after beta-adrenergic blockade. , 1989, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[29]  G. Mensah,et al.  Hemodynamic function at rest, during acute stress, and in the field: predictors of cardiac structure and function 2 years later in youth. , 1999, Hypertension.

[30]  F. Treiber,et al.  Prediction of left ventricular mass in youth with family histories of essential hypertension. , 1998, The American journal of the medical sciences.

[31]  W. Strong,et al.  Prediction of resting cardiovascular functioning in youth with family histories of essential hypertension: A 5-year follow-up , 1997, International journal of behavioral medicine.

[32]  R. Schneider,et al.  The Transcendental Meditation program: reducing the risk of heart disease and mortality and improving quality of life in African Americans. , 2001, Ethnicity & disease.

[33]  F. Treiber,et al.  Central adiposity and hemodynamic functioning at rest and during stress in adolescents , 1998, International Journal of Obesity.

[34]  N. Pugh,et al.  Stress reduction and preventing hypertension: preliminary support for a psychoneuroendocrine mechanism. , 1995, Journal of alternative and complementary medicine.

[35]  N. Kaplan The 6th joint national committee report (JNC-6): new guidelines for hypertension therapy from the USA. , 1998, The Keio journal of medicine.

[36]  A. Alexandroff Once more unto the breach. , 1996, Cancer Immunology, Immunotherapy.

[37]  F. Treiber,et al.  Ethnicity, family history of hypertension and patterns of hemodynamic reactivity in boys. , 1993, Psychosomatic medicine.

[38]  F. Treiber,et al.  Ethnic differences in the myocardial and vascular reactivity to stress in normotensive girls. , 1994, American journal of hypertension.

[39]  H. Davis,et al.  1-Year stability and prediction of cardiovascular functioning at rest and during laboratory stressors in youth with family histories of essential hypertension , 1994, International journal of behavioral medicine.

[40]  P Whelton,et al.  Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988-1991. , 1995, Hypertension.

[41]  O. P. Bagga,et al.  A comparative study of the effect of Transcendental Meditation (T.M.) and Shavasana practice on cardiovascular system. , 1983, Indian heart journal.

[42]  A. Wilson,et al.  A wakeful hypometabolic physiologic state. , 1971, The American journal of physiology.

[43]  A. Baron,et al.  Longitudinal blood pressures in blacks, whites, and Mexican Americans during adolescence and early adulthood. , 1986, American journal of epidemiology.

[44]  N. Cook,et al.  News for the practitioner , 1993, European Journal of Pediatrics.

[45]  J B Stokes,et al.  The national high blood pressure education program. , 1974, Journal of the American Pharmaceutical Association.

[46]  B. Egan,et al.  Trial of stress reduction for hypertension in older African Americans. II. Sex and risk subgroup analysis. , 1996, Hypertension.

[47]  K. Matthews,et al.  Cardiovascular reactivity to stress predicts future blood pressure status. , 1993, Hypertension.

[48]  R. Schneider,et al.  A Randomized Controlled Trial of Stress Reduction for Hypertension in Older African Americans , 1995 .

[49]  R. K. Wallace,et al.  Beta-adrenergic receptor sensitivity in subjects practicing transcendental meditation. , 1990, Journal of psychosomatic research.

[50]  A. Coats,et al.  Doppler ultrasonic measurement of cardiac output: reproducibility and validation. , 1990, European heart journal.

[51]  S. Appelle,et al.  Simple Reaction Time as a Function of Alertness and Prior Mental Activity , 1974, Perceptual and motor skills.

[52]  C. Shear,et al.  Value of childhood blood pressure measurements and family history in predicting future blood pressure status: results from 8 years of follow-up in the Bogalusa Heart Study. , 1986, Pediatrics.

[53]  K. Matthews,et al.  Cardiovascular Reactivity to the Cold Pressor Test as a Predictor of Hypertension , 1989, Hypertension.

[54]  S. Manuck,et al.  Behaviorally-Evoked Cardiovascular Reactivity and Hypertension: Conceptual Issues and Potential Associations , 1990 .

[55]  F. Treiber,et al.  Racial differences in hemodynamic responses to the cold face stimulus in children and adults. , 1990, Psychosomatic medicine.

[56]  L. Beckett,et al.  Serial changes in blood pressure from adolescence into adulthood. , 1992, American journal of epidemiology.

[57]  S. Manuck Cardiovascular reactivity in cardiovascular disease: “Once more unto the breach” , 1994, International journal of behavioral medicine.

[58]  R. Schneider,et al.  Stress, stress reduction, and hypertension in African Americans: an updated review. , 1997, Journal of the National Medical Association.

[59]  B. Brenner,et al.  Hypertension: Pathophysiology, Diagnosis, and Management , 1994 .

[60]  R. Waziri,et al.  Altered Responses of Cortisol, GH, TSH and Testosterone to Acute Stress after Four Months' Practice of Transcendental Meditation (TM) a , 1994, Annals of the New York Academy of Sciences.