Atrial fibrillation detection with multiparametric RR interval feature and machine learning technique

Automatic screening of atrial fibrillation (AF) in the out-of-clinic environment is potentially an effective method for early detection of this life-threatening arrhythmia which is often paroxysmal and asymptomatic. Different technologies such as modified blood pressure monitor, single lead ECG-based finger-probe, and smartphone using plethysmogram signal have been emerging for this purpose. All these technologies use irregularity of RR interval (RRI) as a feature for AF detection. For real-time applications scalar feature is extracted from RRI signal and classified with a threshold. In this work, we have introduced multi-parametric RRI feature yielding a multidimensional feature vector. We used machine learning technique to learn the optimal decision boundary. The proposed method was tested with a publicly available landmark database. Initial experiments show promising AF detection performances comparable to those of state-of-the-art methods. Development and implementation of such a method in existing screen devices such a smartphone could be important for prevention of AFrelated risk of stroke, dementia, and death.

[1]  Naif Alajlan,et al.  An efficient QRS detection method for ECG signal captured from fingers , 2013, 2013 IEEE International Conference on Multimedia and Expo Workshops (ICMEW).

[2]  Corinna Cortes,et al.  Support-Vector Networks , 1995, Machine Learning.

[3]  V. Chair,et al.  Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. , 2014, Stroke.

[4]  Giovanni Calcagnini,et al.  Daily distribution of atrial arrhythmic episodes in sick sinus syndrome patients: implications for atrial arrhythmia monitoring. , 2012, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[5]  Sudha Seshadri,et al.  50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study , 2015, The Lancet.

[6]  Emma Pickwell-MacPherson,et al.  Automatic online detection of atrial fibrillation based on symbolic dynamics and Shannon entropy , 2014, BioMedical Engineering OnLine.

[7]  Matthew Thompson,et al.  Triage tests for identifying atrial fibrillation in primary care: a diagnostic accuracy study comparing single-lead ECG and modified BP monitors , 2014, BMJ Open.

[8]  Naif Alajlan,et al.  Rhythm-based heartbeat duration normalization for atrial fibrillation detection , 2016, Comput. Biol. Medicine.

[9]  D. Linker,et al.  Accurate, Automated Detection of Atrial Fibrillation in Ambulatory Recordings , 2016, Cardiovascular engineering and technology.

[10]  Ki H. Chon,et al.  Atrial Fibrillation Detection Using an iPhone 4S , 2013, IEEE Transactions on Biomedical Engineering.

[11]  G. Stergiou,et al.  Diagnostic accuracy of a home blood pressure monitor to detect atrial fibrillation , 2009, Journal of Human Hypertension.

[12]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[13]  Wanqing Wu,et al.  A Real-Time Atrial Fibrillation Detection Algorithm Based on the Instantaneous State of Heart Rate , 2015, PloS one.

[14]  J. Wiesel,et al.  Detection of atrial fibrillation using a modified microlife blood pressure monitor. , 2009, American journal of hypertension.

[15]  Mark Bowes,et al.  Screening for atrial fibrillation: sensitivity and specificity of a new methodology. , 2011, The British journal of general practice : the journal of the Royal College of General Practitioners.

[16]  Giovanni Calcagnini,et al.  Clinical Validation of an Algorithm for Automatic Detection of Atrial Fibrillation from Single Lead ECG , 2010 .

[17]  Stefano Omboni,et al.  Screening for atrial fibrillation with automated blood pressure measurement: Research evidence and practice recommendations. , 2016, International journal of cardiology.

[18]  J. Mant,et al.  How can we best detect atrial fibrillation? , 2012, The journal of the Royal College of Physicians of Edinburgh.

[19]  Luigi Padeletti,et al.  Usefulness of continuous electrocardiographic monitoring for atrial fibrillation. , 2012, The American journal of cardiology.

[20]  J. Wiesel,et al.  Comparison of the Microlife blood pressure monitor with the Omron blood pressure monitor for detecting atrial fibrillation. , 2014, The American journal of cardiology.

[21]  M. Stridh,et al.  Automatic screening of atrial fibrillation in thumb-ECG recordings , 2012, 2012 Computing in Cardiology.

[22]  Giovanni Calcagnini,et al.  Simulation of monitoring strategies for atrial arrhythmia detection. , 2013, Annali dell'Istituto superiore di sanita.

[23]  Vaidotas Marozas,et al.  Low-complexity detection of atrial fibrillation in continuous long-term monitoring , 2015, Comput. Biol. Medicine.