Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis.
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T. Han | Hongyang Wang | V. Poli | Jin Ding | G. Feng | B. Bailly‐Maitre | H. Zhu | N. Varki | Shuangwei Li | F. Princen | E. Bard-Chapeau | Di Fang | Sharon S. Zhang | B. Bailly-maitre
[1] M. Rao,et al. Activation of Multiple Proto-oncogenic Tyrosine Kinases in Breast Cancer via Loss of the PTPN12 Phosphatase , 2011, Cell.
[2] A. Levine,et al. The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes , 2010, Science.
[3] Ian Blumenthal,et al. Type 1 T Helper Cells Induce the Accumulation of Myeloid‐Derived Suppressor Cells in the Inflamed Tgfb1 Knockout Mouse Liver , 2010, Hepatology.
[4] M. Karin,et al. Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation. , 2010, Cancer cell.
[5] Hua Yu,et al. STATs in cancer inflammation and immunity: a leading role for STAT3 , 2009, Nature Reviews Cancer.
[6] Chris Sander,et al. The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers , 2009, Proceedings of the National Academy of Sciences.
[7] T. Mustelin,et al. A Conserved Mechanism for Control of Human and Mouse Embryonic Stem Cell Pluripotency and Differentiation by Shp2 Tyrosine Phosphatase , 2009, PloS one.
[8] F. Révillion,et al. Expression of the putative tumor suppressor gene PTPN13/PTPL1 is an independent prognostic marker for overall survival in breast cancer , 2009, International journal of cancer.
[9] Y. Agazie,et al. SHP2 is up‐regulated in breast cancer cells and in infiltrating ductal carcinoma of the breast, implying its involvement in breast oncogenesis , 2008, Histopathology.
[10] T. Luedde,et al. Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma , 2007 .
[11] G. Feng,et al. PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase. , 2007, Blood.
[12] T. Luedde,et al. Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. , 2007, Cancer cell.
[13] Hua Yu,et al. Tumour immunology: Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment , 2007, Nature Reviews Immunology.
[14] N. Droin,et al. Concerted Functions of Gab1 and Shp2 in Liver Regeneration and Hepatoprotection , 2006, Molecular and Cellular Biology.
[15] R. Foà,et al. Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease. , 2006, American journal of human genetics.
[16] Su-zhan Zhang,et al. Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia. , 2005, Blood.
[17] Michael Karin,et al. IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis , 2005, Cell.
[18] B. Gelb,et al. Germ-line and somatic PTPN11 mutations in human disease. , 2005, European journal of medical genetics.
[19] G. Feng,et al. Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[20] Michael Karin,et al. IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer , 2004, Cell.
[21] Giovanni Parmigiani,et al. Mutational Analysis of the Tyrosine Phosphatome in Colorectal Cancers , 2004, Science.
[22] G. Feng,et al. The Shp-2 tyrosine phosphatase , 2004 .
[23] G. Feng,et al. A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. , 2003, Blood.
[24] B. Neel,et al. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. , 2003, Trends in biochemical sciences.
[25] J. Licht,et al. Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia , 2003, Nature Genetics.
[26] T. Hunter,et al. Oncogenic kinase signalling , 2001, Nature.
[27] V. Poli,et al. Essential Role of STAT3 in the Control of the Acute-Phase Response as Revealed by Inducible Gene Activation in the Liver , 2001, Molecular and Cellular Biology.
[28] V. Poli,et al. Erratum: Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation in the liver (Molecular and Cellcular Biology (2001) 21 (S) 1621-1632) , 2001 .
[29] Gabriella,et al. Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver. , 2001, Molecular and cellular biology.
[30] G. Feng,et al. Shp-2 Tyrosine Phosphatase Functions as a Negative Regulator of the Interferon-Stimulated Jak/STAT Pathway , 1999, Molecular and Cellular Biology.
[31] Y. Aoki,et al. Coordinate Regulation of STAT Signaling and c-fosExpression by the Tyrosine Phosphatase SHP-2* , 1998, The Journal of Biological Chemistry.
[32] R. Weinberg. The Molecular Basis of Oncogenes and Tumor Suppressor Genes , 1995, Annals of the New York Academy of Sciences.
[33] T. Pawson,et al. SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases. , 1993, Science.
[34] J. Bishop. Molecular themes in oncogenesis , 1991, Cell.
[35] T. Hunter,et al. From c-src to v-src, or the case of the missing C terminus. , 1986, Cancer surveys.
[36] I. M. Neiman,et al. [Inflammation and cancer]. , 1974, Patologicheskaia fiziologiia i eksperimental'naia terapiia.