Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway.
暂无分享,去创建一个
Jae U. Jung | Weiming Yuan | P. Feng | Hee-Sung Park | G. Seo | Q. Liang | Brandon Tan | Aerin Yang | Younho Choi | Sungyoon Kim
[1] A. Kröger,et al. DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity. , 2015, Immunity.
[2] R. Weichselbaum,et al. STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors. , 2014, Immunity.
[3] Ying Wang,et al. STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors. , 2014, Immunity.
[4] Ha Won Kim,et al. Activated STING in a vascular and pulmonary syndrome. , 2014, The New England journal of medicine.
[5] A. García-Sastre,et al. Negative regulation of NF-κB activity by brain-specific TRIpartite Motif protein 9 , 2014, Nature Communications.
[6] V. Hornung,et al. OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids , 2014, Nature Reviews Immunology.
[7] Jonathan L. Schmid-Burgk,et al. TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner , 2014, The Journal of Immunology.
[8] K. Fitzgerald,et al. Recognition of cytosolic DNA by cGAS and other STING‐dependent sensors , 2014, European journal of immunology.
[9] B. Oh,et al. Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses. , 2014, Cell host & microbe.
[10] Zhijian J. Chen,et al. Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects , 2013, Science.
[11] Nan Yan,et al. Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses , 2013, Science.
[12] J. Berger,et al. Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity. , 2013, Cell reports.
[13] V. Hornung,et al. cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING , 2013, Nature.
[14] D. Söll,et al. A facile strategy for selective incorporation of phosphoserine into histones. , 2013, Angewandte Chemie.
[15] A. Bowie,et al. Immune sensing of DNA. , 2013, Immunity.
[16] Roger A. Jones,et al. Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase , 2013, Cell.
[17] Zhijian J. Chen,et al. Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway , 2013, Science.
[18] Zhijian J. Chen,et al. Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA , 2013, Science.
[19] H. Ren,et al. DNA-PK is a DNA sensor for IRF-3-dependent innate immunity , 2012, eLife.
[20] R. Martuza,et al. Effect of γ34.5 Deletions on Oncolytic Herpes Simplex Virus Activity in Brain Tumors , 2012, Journal of Virology.
[21] J. Connor,et al. HijAkt , 2012, Progress in Molecular Biology and Translational Science.
[22] Stephan Ludwig,et al. Phosphatidylinositol‐3‐kinase (PI3K) is activated by influenza virus vRNA via the pathogen pattern receptor Rig‐I to promote efficient type I interferon production , 2011, Cellular microbiology.
[23] Yong‐jun Liu,et al. The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells , 2011, Nature Immunology.
[24] D. Söll,et al. Expanding the Genetic Code of Escherichia coli with Phosphoserine , 2011, Science.
[25] E. Elinav,et al. Regulation of the antimicrobial response by NLR proteins. , 2011, Immunity.
[26] S. Akira,et al. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. , 2011, Immunity.
[27] Y. Yang,et al. ICP34.5 Protein of Herpes Simplex Virus Facilitates the Initiation of Protein Translation by Bridging Eukaryotic Initiation Factor 2α (eIF2α) and Protein Phosphatase 1* , 2011, The Journal of Biological Chemistry.
[28] M. White,et al. TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation. , 2011, Molecular cell.
[29] A. Bowie,et al. IFI16 is an innate immune sensor for intracellular DNA , 2010, Nature Immunology.
[30] E. Latz. The inflammasomes: mechanisms of activation and function. , 2010, Current opinion in immunology.
[31] Zhijian J. Chen,et al. RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway , 2009, Cell.
[32] V. Hornung,et al. RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate , 2009, Nature Immunology.
[33] L. P. de Sousa,et al. Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication , 2009, Journal of Virology.
[34] J. Lünemann,et al. Antiviral immune responses: triggers of or triggered by autoimmunity? , 2009, Nature Reviews Immunology.
[35] Jasmyn A. Dunn,et al. HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA , 2009, Science.
[36] E. Alnemri,et al. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA , 2009, Nature.
[37] Daniel R. Caffrey,et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1 activating inflammasome with ASC , 2009, Nature.
[38] A. Verma,et al. Dual Regulatory Roles of Phosphatidylinositol 3-Kinase in IFN Signaling1 , 2008, The Journal of Immunology.
[39] Zhengfan Jiang,et al. TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages. , 2008, Molecular immunology.
[40] L. Platanias,et al. Role of the Akt pathway in mRNA translation of interferon-stimulated genes , 2008, Proceedings of the National Academy of Sciences.
[41] K. Honda,et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response , 2007, Nature.
[42] Lewis C. Cantley,et al. AKT/PKB Signaling: Navigating Downstream , 2007, Cell.
[43] Wei Zhang,et al. HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. , 2007, Cell host & microbe.
[44] C. Janeway,et al. The Toll receptor family and microbial recognition. , 2000, Trends in microbiology.