A Simple instrumentation calibration technique for Electrical Impedance Tomography (EIT) using a 16-electrode phantom

A simple analog instrumentation for Electrical Impedance Tomography is developed and calibrated using the practical phantoms. A constant current injector consisting of a modified Howland voltage controlled current source fed by a voltage controlled oscillator is developed to inject a constant current to the phantom boundary. An instrumentation amplifier, 50 Hz notch filter and a narrow band pass filter are developed and used for signal conditioning. Practical biological phantoms are developed and the forward problem is studied to calibrate the EIT-instrumentation. An array of sixteen stainless steel electrodes is developed and placed inside the phantom tank filled with KCl solution. 1 mA, 50 kHz sinusoidal current is injected at the phantom boundary using adjacent current injection protocol. The differential potentials developed at the voltage electrodes are measured for sixteen current injections. Differential voltage signal is passed through an instrumentation amplifier and a filtering block and measured by a digital multimeter. A forward solver is developed using Finite Element Method in MATLAB7.0 for solving the EIT governing equation. Differential potentials are numerically calculated using the forward solver with a simulated current and bathing solution conductivity. Measured potential data is compared with the differential potentials calculated for calibrating the instrumentation to acquire the voltage data suitable for better image reconstruction.

[1]  Philippe Renaud,et al.  Cell Culture Imaging Using Microimpedance Tomography , 2008, IEEE Transactions on Biomedical Engineering.

[2]  J Rosell,et al.  Common-mode feedback in electrical impedance tomography. , 1992, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics.

[3]  Thomas J. Yorkey,et al.  Comparing reconstruction methods for electrical impedance tomography , 1987, Annals of Biomedical Engineering.

[4]  Richard H. Bayford,et al.  Electrical impedance tomography of human brain function using reconstruction algorithms based on the finite element method , 2003, NeuroImage.

[5]  D S Holder,et al.  Some practical biological phantoms for calibrating multifrequency electrical impedance tomography. , 1996, Physiological measurement.

[6]  David Isaacson,et al.  Electrical Impedance Tomography , 1999, SIAM Rev..

[7]  C. J. Grootveld Measuring & modeling of concentrated settling suspensions using electrical impedance tomography , 1996 .

[8]  Christin Wirth The Essential Physics of Medical Imaging , 2003, European Journal of Nuclear Medicine and Molecular Imaging.

[9]  Nathan Ida,et al.  Introduction to the Finite Element Method , 1997 .

[10]  R. Granit THE HEART ( Extract from “ Principles and Applications of Bioelectric and Biomagnetic Fields , 2005 .

[11]  Brian H. Brown,et al.  Medical impedance tomography and process impedance tomography: a brief review , 2001 .

[12]  T. Hope,et al.  Technology review: The use of electrical impedance scanning in the detection of breast cancer , 2003, Breast Cancer Research.

[13]  Y. L. Mo,et al.  Increasing image resolution in electrical impedance tomography , 2002 .

[14]  Hung-Yuan Chung,et al.  The Scanning Data Collection Strategy for Enhancing the Quality of Electrical Impedance Tomography , 2008, IEEE Transactions on Instrumentation and Measurement.

[15]  Ying Li,et al.  A novel combination method of electrical impedance tomography inverse problem for brain imaging , 2005, IEEE Transactions on Magnetics.

[16]  David Barber,et al.  Three dimensional electrical impedance tomography of the human thorax , 1996, Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[17]  B. M. Graham,et al.  Enhancements in Electrical Impedance Tomography (EIT) image reconstruction for three-dimensional lung imaging , 2007 .

[18]  E Atalar,et al.  Electrical impedance tomography of translationally uniform cylindrical objects with general cross-sectional boundaries. , 1990, IEEE transactions on medical imaging.

[19]  Robert Plonsey,et al.  Bioelectromagnetism: Principles and Applications of Bioelectric and Biomagnetic Fields , 1995 .

[20]  Denyer Cwl Electronics for real-time and three-dimensional electrical impedance tomographs. , 1996 .

[21]  L Tarassenko,et al.  Impedance imaging in the newborn. , 1987, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics.