Determinants of Vaccination Coverage for the Second Dose of Measles-Rubella Vaccine in Tokyo, Japan.

In Japan, some measles outbreaks were initiated by a tourist from oversea and foreign workers recently. Moreover, rubella outbreak emerged since July 2018 mainly in the South Kanto, and the outbreak is currently ongoing in 2019. It is important to maintain a high measles-rubella combined vaccine (MR) coverage for measles-rubella control. Vaccination coverage for the second dose of MR (MR2) is 90.8% in Tokyo in 2016, which was the third worst among all prefectures in Japan. The purpose of this study was to clarify determinant factors of vaccination coverage for MR2 in Tokyo. Data were obtained for 49 wards and cities in Tokyo in 2016. We regressed vaccination coverage of MR2 on the times of notification by mail, the proportion of households receiving welfare payments, and the proportion of non-Japanese elementary school students. In addition to the simplest specification, five factors were included separately as explanatory variables: the proportion of public health nurses; the ratio of the number of pediatric medical facilities to the number of preschool and elementary school children; the moving-in rate; the proportion of households with a single parent; and the proportion of households with husband and wife both working. Results show that a high proportion of households receiving welfare payments, notification by two or more letters, and moving-in rate or a lower proportion of non-Japanese elementary school students improve coverage. In conclusion, the health authorities can exert efforts to reduce burden of time spent for vaccination and provide sufficient information to improve coverage.

[1]  T. Matsunaga,et al.  Low anti-rubella antibody levels in public facilities staff in Tokyo. , 2019, Lancet. Infectious Diseases (Print).

[2]  A. Kraemer,et al.  Heterogeneity in coverage for measles and varicella vaccination in toddlers – analysis of factors influencing parental acceptance , 2017, BMC Public Health.

[3]  Matías Busso,et al.  Did you get your shots? Experimental evidence on the role of reminders. , 2015, Journal of health economics.

[4]  I. Kawachi,et al.  Correlation Between Pediatrician Supply and Public Health in Japan as Evidenced by Vaccination Coverage in 2010: Secondary Data Analysis , 2015, Journal of epidemiology.

[5]  J. Sales,et al.  Impact of a physician recommendation and parental immunization attitudes on receipt or intention to receive adolescent vaccines , 2013, Human vaccines & immunotherapeutics.

[6]  David K Vawdrey,et al.  Effect of a text messaging intervention on influenza vaccination in an urban, low-income pediatric and adolescent population: a randomized controlled trial. , 2012, JAMA.

[7]  S. Humiston,et al.  Parental Delay or Refusal of Vaccine Doses, Childhood Vaccination Coverage at 24 Months of Age, and the Health Belief Model , 2011, Public health reports.

[8]  A. Chevalier,et al.  Anatomy of a health scare: education, income and the MMR controversy in the UK. , 2011, Journal of health economics.

[9]  S. Omer,et al.  Attitudes and Beliefs of Parents Concerned About Vaccines: Impact of Timing of Immunization Information , 2011, Pediatrics.

[10]  M. Goodman,et al.  Identification and characteristics of vaccine refusers , 2009, BMC pediatrics.

[11]  Katherine J. Griswold,et al.  Postpartum Mothers’ Attitudes, Knowledge, and Trust Regarding Vaccination , 2008, Maternal and Child Health Journal.

[12]  L. Barker,et al.  Children who have received no vaccines: who are they and where do they live? , 2004, Pediatrics.

[13]  E. Luman,et al.  U.S. children living in and near poverty: risk of vaccine-preventable diseases. , 2001, American journal of preventive medicine.

[14]  M. Hirayama Rubella and congenital rubella syndrome in Japan. , 1970, Paediatria Universitatis Tokyo.

[15]  Yutaro Sakai The Vaccination Kuznets Curve: Do vaccination rates rise and fall with income? , 2018, Journal of health economics.

[16]  Melbourne Victoria,et al.  A Ministry of Health , 1917, Nature.