TGF-β-induced hepatocyte lincRNA-p21 contributes to liver fibrosis in mice

[1]  Jian Wang,et al.  Lipopolysaccharide promotes pulmonary fibrosis in acute respiratory distress syndrome (ARDS) via lincRNA-p21 induced inhibition of Thy-1 expression , 2016, Molecular and Cellular Biochemistry.

[2]  Jianjian Zheng,et al.  lincRNA‐p21 inhibits hepatic stellate cell activation and liver fibrogenesis via p21 , 2015, The FEBS journal.

[3]  Junfeng Zhang,et al.  MicroRNA-30 Protects Against Carbon Tetrachloride-induced Liver Fibrosis by Attenuating Transforming Growth Factor Beta Signaling in Hepatic Stellate Cells. , 2015, Toxicological sciences : an official journal of the Society of Toxicology.

[4]  B. Zhao,et al.  APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p , 2015, Nature Communications.

[5]  Runsheng Chen,et al.  The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling. , 2015, Cell stem cell.

[6]  R. Kong,et al.  SP1-induced upregulation of the long noncoding RNA TINCR regulates cell proliferation and apoptosis by affecting KLF2 mRNA stability in gastric cancer , 2015, Oncogene.

[7]  C. Sensen,et al.  LincRNA-p21 acts as a mediator of ING1b-induced apoptosis , 2015, Cell Death and Disease.

[8]  Jonathan R. Hall,et al.  Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes , 2015, Cell Death and Disease.

[9]  Guocheng Yuan,et al.  LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle Cell Proliferation, Apoptosis, and Atherosclerosis by Enhancing p53 Activity , 2014, Circulation.

[10]  T. Luedde,et al.  Cell death and cell death responses in liver disease: mechanisms and clinical relevance. , 2014, Gastroenterology.

[11]  Junfeng Zhang,et al.  MicroRNA‐101 suppresses liver fibrosis by targeting the TGFβ signalling pathway , 2014, The Journal of pathology.

[12]  S. Verjovski-Almeida,et al.  Long non-coding RNA INXS is a critical mediator of BCL-XS induced apoptosis , 2014, Nucleic acids research.

[13]  S. Verjovski-Almeida,et al.  Long non-coding RNA INXS is a critical mediator of BCL-XS induced apoptosis , 2014, Nucleic acids research.

[14]  Shuhan Sun,et al.  A long noncoding RNA activated by TGF-β promotes the invasion-metastasis cascade in hepatocellular carcinoma. , 2014, Cancer cell.

[15]  P. Sharp,et al.  LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint. , 2014, Molecular cell.

[16]  Xuetao Cao,et al.  The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation , 2014, Science.

[17]  C. Ruiz,et al.  Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients , 2014, Hepatology.

[18]  E. Seki,et al.  Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice , 2014, Hepatology.

[19]  Fan Yang,et al.  Reciprocal regulation of HIF-1α and lincRNA-p21 modulates the Warburg effect. , 2014, Molecular cell.

[20]  R. Schwabe,et al.  Fate-tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its etiology , 2013, Nature Communications.

[21]  M. Waters,et al.  Differential expression of long noncoding RNAs in the livers of female B6C3F1 mice exposed to the carcinogen furan. , 2013, Toxicological sciences : an official journal of the Society of Toxicology.

[22]  J. Rinn,et al.  Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2 , 2013, Genome Biology.

[23]  Feng Liu,et al.  Long noncoding RNAs associated with liver regeneration 1 accelerates hepatocyte proliferation during liver regeneration by activating Wnt/β‐Catenin signaling , 2013, Hepatology.

[24]  E. Park,et al.  Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1. , 2013, Gastroenterology.

[25]  K. Morris,et al.  A pseudogene long noncoding RNA network regulates PTEN transcription and translation in human cells , 2013, Nature Structural &Molecular Biology.

[26]  Kotb Abdelmohsen,et al.  LincRNA-p21 suppresses target mRNA translation. , 2012, Molecular cell.

[27]  Wei Li,et al.  The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type , 2012, Proceedings of the National Academy of Sciences.

[28]  Junfeng Zhang,et al.  miR-30 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in hepatocyte by targeting Snail1. , 2012, Biochemical and biophysical research communications.

[29]  D. Cacchiarelli,et al.  A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA , 2011, Cell.

[30]  J. Ladero Noninvasive Evaluation of Liver Fibrosis in Patients with Chronic Hepatitis C , 2011, Hepatitis monthly.

[31]  Wei Li,et al.  Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice. , 2011, The Journal of clinical investigation.

[32]  T. Luedde,et al.  Micro‐RNA profiling reveals a role for miR‐29 in human and murine liver fibrosis , 2011, Hepatology.

[33]  J. Rinn,et al.  A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response , 2010, Cell.

[34]  Scott L. Friedman,et al.  Evolving challenges in hepatic fibrosis , 2010, Nature Reviews Gastroenterology &Hepatology.

[35]  S. Akira,et al.  Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis , 2009, Proceedings of the National Academy of Sciences.

[36]  Marcus Schuchmann,et al.  Knockout of myeloid cell leukemia‐1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes , 2009, Hepatology.

[37]  W. Rottbauer,et al.  MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts , 2008, Nature.

[38]  Natalie J Torok,et al.  Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo , 2006, Hepatology.

[39]  J. Mattick,et al.  Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome. , 2005, Genome research.

[40]  N. Rajewsky,et al.  Silencing of microRNAs in vivo with ‘antagomirs’ , 2005, Nature.

[41]  D. Brenner,et al.  Erratum: Liver fibrosis (Journal of Clinical Investigation (2005) 115 (209-218) DOI:10.1172/JCI200524282) , 2005 .

[42]  Takahiro Suzuki,et al.  Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses. , 2004, Gastroenterology.

[43]  Hartmut Jaeschke,et al.  Apoptosis and necrosis in liver disease , 2004, Liver international : official journal of the International Association for the Study of the Liver.

[44]  J. Massagué,et al.  A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. , 2003, Molecular cell.

[45]  S. K. Zaidi,et al.  Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[46]  S. Dooley,et al.  Roles of TGF-beta in hepatic fibrosis. , 2002, Frontiers in bioscience : a journal and virtual library.

[47]  K. Zatloukal,et al.  Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA. , 2007, Gastroenterology.