Desktop fast-field cycling nuclear magnetic resonance relaxometer.

In this paper a new type of Fast Field Cycling (FFC) Nuclear Magnetic Resonance (NMR) relaxometer with low power consumption (200W) and cycle to cycle field stability better than 10(-4) is described. The new high-permeability magnet was designed to allow for good magnetic field homogeneity and allows for the sample rotation around an axis perpendicular to magnetic field, operating with magnetic fields between 0 and 0.21T. The power supply of the new relaxometer was specially developed in order to have steady state accurate currents and allow for magnetic field switching times less than 3ms. Additional control circuits were developed and included to compensate the Earth magnetic field component parallel to the field axis and to compensate for parasitic currents. The main aspects of the developed circuits together with some calibrating experimental results using the liquid crystal compounds 5CB and 8CB are presented and discussed.

[1]  F. Noack,et al.  NMR field-cycling spectroscopy: principles and a]lications , 1986 .

[2]  K. H Schweikert,et al.  A high-field air-cored magnet coil design for fast-field-cycling NMR , 1988 .

[3]  S. Dvinskikh,et al.  Magnet design with high B(0) homogeneity for fast-field-cycling NMR applications. , 2001, Journal of magnetic resonance.

[4]  J. Fitzsimmons,et al.  Maximizing signal-to-noise ratio in the presence of coil coupling. , 1996, Journal of magnetic resonance. Series B.

[5]  S. Žumer,et al.  Field-cycling NMR relaxometry of a liquid crystal above in mesoscopic confinement. , 2005, Physical review. E, Statistical, nonlinear, and soft matter physics.

[6]  M.A. Morich Novel Gradient coil set with an Interstitial gap for Interventionl Nuclear Magnetic Resonance Application , 1997, 1997 IEEE International Magnetics Conference (INTERMAG'97).

[7]  A. Abdel-azim Fundamentals of Heat and Mass Transfer , 2011 .

[8]  G. Marques,et al.  New isolated gate bipolar transistor two-quadrant chopper power supply for a fast field cycling nuclear magnetic resonance spectrometer , 2003 .

[9]  F. Kreith,et al.  Principles of heat transfer , 1962 .

[10]  R. Y. Dong Nuclear magnetic resonance spectroscopy of liquid crystals , 2009 .

[11]  Constantin Job,et al.  Fast field‐cycling nuclear magnetic resonance spectrometer , 1996 .

[12]  Albert Macovski,et al.  Homogeneous magnet design using linear programming , 2000 .

[13]  J. Struppe,et al.  Angular and frequency dependent spin relaxation study of liquid crystalline cyanobiphenyls , 1996 .

[14]  U. Tietze,et al.  Electronic circuits : design and applications , 1991 .

[15]  Jens H. Jensen Minimum-volume coil arrangements for generation of uniform magnetic fields , 2002 .

[16]  C. Cruz,et al.  Advances in Proton NMR Relaxometry in Thermotropic Liquid Crystals , 2009 .

[17]  Martin N. Wilson,et al.  Superconducting Magnets , 1984 .

[19]  E. Anoardo,et al.  Fast-field-cycling NMR: Applications and instrumentation , 2001 .

[20]  M. W. Garrett,et al.  Thick Cylindrical Coil Systems for Strong Magnetic Fields with Field or Gradient Homogeneities of the 6th to 20th Order , 1967 .

[21]  S. Žumer,et al.  Liquid crystal 8CB in random porous glass: NMR relaxometry study of molecular diffusion and director fluctuations. , 2007, Physical review. E, Statistical, nonlinear, and soft matter physics.

[22]  G. Marques,et al.  Novel pulsed switched power supply for a fast field cycling NMR spectrometer. , 2004, Solid state nuclear magnetic resonance.

[23]  R. Kimmich NMR: Tomography, Diffusometry, Relaxometry , 2001 .

[24]  H. Carr,et al.  The Principles of Nuclear Magnetism , 1961 .