Assessment factors--applications in health risk assessment of chemicals.
暂无分享,去创建一个
Agneta Falk-Filipsson | Maria Wallén | Annika Hanberg | Katarina Victorin | A. Hanberg | A. Falk-Filipsson | K. Victorin | M. Warholm | Maria Wallén | Margareta Warholm
[1] Lesa L Aylward,et al. An evaluation of benchmark dose methodology for non-cancer continuous-data health effects in animals due to exposures to dioxin (TCDD). , 2004, Regulatory toxicology and pharmacology : RTP.
[2] H. Feldman,et al. The 3/4 mass exponent for energy metabolism is not a statistical artifact. , 1983, Respiration physiology.
[3] H. Kay. Environmental Health Criteria , 1980 .
[4] M L Dourson,et al. An Approach for Modeling Noncancer Dose Responses with an Emphasis on Uncertainty , 1997, Risk analysis : an official publication of the Society for Risk Analysis.
[5] D. Hattis,et al. Distributions of Individual Susceptibility among Humans for Toxic Effects: How Much Protection Does the Traditional Tenfold Factor Provide for What Fraction of Which Kinds of Chemicals and Effects? , 1999, Annals of the New York Academy of Sciences.
[6] W. Slob,et al. Mathematical modelling and quantitative methods. , 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[7] J. Dorne. Impact of inter‐individual differences in drug metabolism and pharmacokinetics on safety evaluation , 2004, Fundamental & clinical pharmacology.
[8] H J Clewell,et al. Incorporation of pharmacokinetics in noncancer risk assessment: example with chloropentafluorobenzene. , 1994, Risk analysis : an official publication of the Society for Risk Analysis.
[9] Monique A J Rennen,et al. Oral-to-inhalation route extrapolation in occupational health risk assessment: a critical assessment. , 2004, Regulatory toxicology and pharmacology : RTP.
[10] E J Calabrese,et al. Uncertainty factors and interindividual variation. , 1985, Regulatory toxicology and pharmacology : RTP.
[11] W Slob,et al. Assessment factors for human health risk assessment: a discussion paper. , 1999, Critical reviews in toxicology.
[12] E. Mark,et al. Polymorphisms in the Dna Repair Genes Xrcc1 and Ercc2 and Biomarkers of Dna Damage in Human Blood Mononuclear Cells Cross-complementing Group 1) than in 399arg/arg Carriers of Breaks following Base Excision Repair (ber) Resulting From , 2022 .
[13] B. Weiss. Sexually dimorphic nonreproductive behaviors as indicators of endocrine disruption. , 2002, Environmental health perspectives.
[14] J. Sastre,et al. Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males. , 2003, Free radical biology & medicine.
[15] K Walton,et al. Uncertainty factors for chemical risk assessment: interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates. , 2001, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[16] R. Parshad,et al. XPD polymorphisms: effects on DNA repair proficiency. , 2000, Carcinogenesis.
[17] J. Yokota,et al. Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA , 1998, Oncogene.
[18] S G Selevan,et al. Identifying critical windows of exposure for children's health. , 2000, Environmental health perspectives.
[19] Wout Slob,et al. A comparison of ratio distributions based on the NOAEL and the benchmark approach for subchronic-to-chronic extrapolation. , 2005, Toxicological sciences : an official journal of the Society of Toxicology.
[20] Salomon Sand,et al. Evaluation of the benchmark dose method for dichotomous data: model dependence and model selection. , 2002, Regulatory toxicology and pharmacology : RTP.
[21] A. Dirksen,et al. Incidence of allergic contact sensitization in Danish adults between 1990 and 1998; the Copenhagen Allergy Study, Denmark , 2002, The British journal of dermatology.
[22] Michael Dourson,et al. Differential sensitivity of children and adults to chemical toxicity. I. Biological basis. , 2002, Regulatory toxicology and pharmacology : RTP.
[23] Salomon Sand,et al. The Benchmark Dose Method—Review of Available Models, and Recommendations for Application in Health Risk Assessment , 2003, Critical reviews in toxicology.
[24] R. Menne. Textbook of Contact Dermatitis , 1995, Springer Berlin Heidelberg.
[25] K Walton,et al. Species-specific uncertainty factors for compounds eliminated principally by renal excretion in humans. , 2004, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[26] D Krewski,et al. Procedures for calculating benchmark doses for health risk assessment. , 1998, Regulatory toxicology and pharmacology : RTP.
[27] D Hattis,et al. Human variability in susceptibility to toxic chemicals--a preliminary analysis of pharmacokinetic data from normal volunteers. , 1987, Risk analysis : an official publication of the Society for Risk Analysis.
[28] M. Abdel‐Rahman,et al. Evaluation of the use of uncertainty factors in deriving RfDs for some chlorinated compounds. , 1995, Journal of toxicology and environmental health.
[29] U. Tillmann,et al. A systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data. , 1997, Regulatory toxicology and pharmacology : RTP.
[30] G. Coetzee,et al. Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China , 2000, The Lancet.
[31] F P Perera,et al. Molecular epidemiology: insights into cancer susceptibility, risk assessment, and prevention. , 1996, Journal of the National Cancer Institute.
[32] A G Renwick,et al. Toxicokinetics in infants and children in relation to the ADI and TDI. , 1998, Food additives and contaminants.
[33] D W Gaylor,et al. Issues in qualitative and quantitative risk analysis for developmental toxicology. , 1988, Risk analysis : an official publication of the Society for Risk Analysis.
[34] M. Spitz,et al. Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S-transferase theta. , 1995, Carcinogenesis.
[35] K Walton,et al. Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review. , 2005, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[36] M L Dourson,et al. Regulatory history and experimental support of uncertainty (safety) factors. , 1983, Regulatory toxicology and pharmacology : RTP.
[37] R. Garnier,et al. Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning. , 1996, Occupational and environmental medicine.
[38] K. Schneider,et al. Allometric principles for interspecies extrapolation in toxicological risk assessment--empirical investigations. , 2004, Regulatory toxicology and pharmacology : RTP.
[39] K S Crump,et al. A new method for determining allowable daily intakes. , 1984, Fundamental and applied toxicology : official journal of the Society of Toxicology.
[40] Wout Slob,et al. Dose-response modeling of continuous endpoints. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.
[41] V. Ribeiro,et al. CYP3A4*1B and NAT2*14 Alleles in a Native African Population , 2003, Clinical chemistry and laboratory medicine.
[42] K. Richert-Boe,et al. Glutathione S-transferase M1 (GSTM1) deficiency and lung cancer risk. , 1995, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[43] Xi,et al. Benzene poisoning, a risk factor for hematological malignancy, is associated with the NQO1 609C-->T mutation and rapid fractional excretion of chlorzoxazone. , 1997, Cancer research.
[44] Derek J. Knight,et al. Annex: Directive 98/8/EC of the European Parliament and of the Council of 16 February 1998 Concerning the Placing of Biocidal Products on the Market , 2002 .
[45] K Walton,et al. Uncertainty factors for chemical risk assessment. human variability in the pharmacokinetics of CYP1A2 probe substrates. , 2001, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[46] Michael Dourson,et al. A Probabilistic Framework for the Reference Dose (Probabilistic RfD) , 1998 .
[47] M. Brockhaus,et al. The effects of β-estradiol on SHSY5Y neuroblastoma cells during heavy metal induced oxidative stress, neurotoxicity and β-amyloid secretion , 2002, Neuroscience.
[48] S. Bonenfant,et al. How is sex considered in recent epidemiological publications on occupational risks? , 2000, Occupational and environmental medicine.
[49] A. Renwick. Data-derived safety factors for the evaluation of food additives and environmental contaminants. , 1993, Food additives and contaminants.
[50] E. Silbergeld,et al. Chemicals and menopause: effects on age at menopause and on health status in the postmenopausal period. , 1999, Journal of women's health.
[51] Harvey J Clewell,et al. Evaluation of the potential impact of age- and gender-specific pharmacokinetic differences on tissue dosimetry. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.
[52] C. Kimmel,et al. Dose-response assessment for developmental toxicity. II. Comparison of generic benchmark dose estimates with no observed adverse effect levels. , 1994, Fundamental and applied toxicology : official journal of the Society of Toxicology.
[53] M. Pieters,et al. Evaluation of the uncertainty factor for subchronic-to-chronic extrapolation: statistical analysis of toxicity data. , 1998, Regulatory toxicology and pharmacology : RTP.
[54] Edward V. Sargent,et al. Use of toxicokinetic and toxicodynamic data to reduce uncertainties when setting occupational exposure limits for pharmaceuticals , 1997 .
[55] A G Renwick,et al. Safety factors and establishment of acceptable daily intakes. , 1991, Food additives and contaminants.
[56] Kenny S. Crump,et al. Calculation of Benchmark Doses from Continuous Data , 1995 .
[57] J. Dorne,et al. Human variability in the renal elimination of foreign compounds and renal excretion-related uncertainty factors for risk assessment. , 2004, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[58] J. Dorne,et al. Uncertainty factors for chemical risk assessment: interspecies differences in glucuronidation. , 2001, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[59] J. Dorne,et al. Human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for risk assessment. , 2003, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[60] Magnus Ingelman-Sundberg,et al. Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future. , 2004, Trends in pharmacological sciences.
[61] M L Dourson,et al. Evolution of science-based uncertainty factors in noncancer risk assessment. , 1996, Regulatory toxicology and pharmacology : RTP.
[62] L. Tuxen,et al. Integrated risk information system (IRIS) , 1990 .
[63] K Walton,et al. Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate? , 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[64] D. Hattis,et al. Evaluation of child/adult pharmacokinetic differences from a database derived from the therapeutic drug literature. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.
[65] W. Slob,et al. A Probabilistic Approach for Deriving Acceptable Human Intake Limits and Human Health Risks from Toxicological Studies: General Framework , 1998 .
[66] Ulrike Schuhmacher-Wolz,et al. Uncertainty in toxicological risk assessment for non-carcinogenic health effects. , 2003, Regulatory toxicology and pharmacology : RTP.
[67] D. Hattis,et al. Differences in Pharmacokinetics Between Children and Adults—II. Children's Variability in Drug Elimination Half‐Lives and in Some Parameters Needed for Physiologically‐Based Pharmacokinetic Modeling , 2003, Risk analysis : an official publication of the Society for Risk Analysis.
[68] R L Kodell,et al. Upper confidence limits on excess risk for quantitative responses. , 1993, Risk analysis : an official publication of the Society for Risk Analysis.
[69] J. Dorne,et al. Polymorphic CYP2C19 and N-acetylation: human variability in kinetics and pathway-related uncertainty factors. , 2003, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[70] J. Brent,et al. Derivation of a chemical-specific adjustment factor (CSAF) for use in the assessment of risk from chronic exposure to ethylene glycol: application of International Programme for Chemical Safety guidelines. , 2005, Toxicology and applied pharmacology.
[71] W Slikker,et al. Risk assessment for neurotoxic effects. , 1990, Neurotoxicology.
[72] Agneta Falk Filipsson,et al. Benchmark Calculations in Risk Assessment Using Continuous Dose‐Response Information: The Influence of Variance and the Determination of a Cut‐Off Value , 2003, Risk analysis : an official publication of the Society for Risk Analysis.
[73] K Walton,et al. Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation). , 2004, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[74] S. Ekman,et al. Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison , 2004, Xenobiotica; the fate of foreign compounds in biological systems.
[75] A G Renwick,et al. Human variability and noncancer risk assessment--an analysis of the default uncertainty factor. , 1998, Regulatory toxicology and pharmacology : RTP.
[76] David E. Burmaster,et al. Human Interindividual Variability in Parameters Related to Health Risks , 1999, Risk analysis : an official publication of the Society for Risk Analysis.
[77] O. G. Fitzhugh,et al. 100-Fold margin of safety , 1954 .
[78] K Walton,et al. An analysis of the need for an additional uncertainty factor for infants and children. , 2000, Regulatory toxicology and pharmacology : RTP.
[79] J. Dorne,et al. Human variability in glucuronidation in relation to uncertainty factors for risk assessment. , 2001, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.